Projects per year
Personal profile
Research interests
Psoriasis: treatments, national and international guidelines, prospective registers, outcome parameters, nail psoriasis, maintenance treatments, therapeutic drug monitoring
Atopic dermatitis: diagnostic criteria, outcomeparameters, treatments, prospective register, therapeutic drug monitoring
Off-label drug use in dermatology: systematic reviews in order to develop national guidelines
Vascular malformations: diagnostic criteria, core outcome set development
Congenital Melanocytic Naevi: core outcome set development
Evidence based dermatology: critical appraised topics, systematic reviews, outcome parameters (core outcome sets), guidelines, shared decision making
specialisation
Education/Academic qualification
Clinical evidence for the treatment of moderate to severe psoriasis. University of Amsterdam, UvA Faculty of Medicine (AMC)
… → 26 Sept 2002
Award Date: 26 Sept 2002
Keywords
- RL Dermatology
- evidence based dermatology, guidelines, systematic reviews, core outcome sets, shared decision making, psoriasis, atopic dermatitis
Collaborations and top research areas from the last five years
Projects
- 4 Active
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TREAT NL: TREatment of ATopic eczema registry - The Netherlands
Gerbens, L., Spuls, P. & Middelkamp Hup, M.
1/06/2017 → …
Project: Research
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Spuls Ph.I.: dermato-immunology and dermato-epidemiology
Bik, C., Busard, C., Gerbens, L., Horbach, S., van der Kraaij, G., Roekevisch, E., Vermeulen, M., de Vries, A. C., Spuls, P., van der Linden, M., Middelkamp Hup, M., Borgonjen, R., Zweegers, J. & Garritsen, F.
1/01/2010 → …
Project: Research
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A randomized trial of methotrexate versus azathioprine for severe atopic eczema
Schram, M. E., Roekevisch, E., Leeflang, M. M. G., Bos, J. D., Schmitt, J. & Spuls, P. I., 2011, In: Journal of allergy and clinical immunology. 128, 2, p. 353-359Research output: Contribution to journal › Article › Academic › peer-review
210 Citations (Scopus) -
Efficacy and safety of systemic treatments for moderate-to-severe atopic dermatitis: a systematic review
Roekevisch, E., Spuls, P. I., Kuester, D., Limpens, J. & Schmitt, J., 2014, In: Journal of allergy and clinical immunology. 133, 2, p. 429-438Research output: Contribution to journal › Review article › Academic › peer-review
261 Citations (Scopus) -
The Harmonizing Outcome Measures for Eczema (HOME) roadmap: a methodological framework to develop core sets of outcome measurements in dermatology
Schmitt, J., Apfelbacher, C., Spuls, P. I., Thomas, K. S., Simpson, E. L., Furue, M., Chalmers, J. & Williams, H. C., 2015, In: Journal of Investigative Dermatology. 135, 1, p. 24-30Research output: Contribution to journal › Article › Academic › peer-review
184 Citations (Scopus) -
Vitiligo-Like Depigmentation in Patients With Stage III-IV Melanoma Receiving Immunotherapy and Its Association With Survival: A Systematic Review and Meta-Analysis
Teulings, H-E., Limpens, J., Jansen, S. N., Zwinderman, A. H., Reitsma, J. B., Spuls, P. I. & Luiten, R. M., 2015, In: Journal of clinical oncology. 33, 7, p. 773-781Research output: Contribution to journal › Review article › Academic › peer-review
469 Citations (Scopus) -
Patient-Oriented Eczema Measure (POEM), a core instrument to measure symptoms in clinical trials: a Harmonising Outcome Measures for Eczema (HOME) statement
the HOME initiative collaborators, 1 Apr 2017, In: British Journal of Dermatology. 176, 4, p. 979-984 6 p.Research output: Contribution to journal › Article › Academic › peer-review
136 Citations (Scopus)
Datasets
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On which evidence can we rely when prescribing off-label methotrexate in dermatological practice? – a systematic review with GRADE approach
van Huizen, A. (Creator), Vermeulen, F. M. (Creator), Bik, C. M. J. M. (Creator), Borgonjen, R. (Creator), Karsch, S. A. T. (Creator), Kuin, R. A. (Creator), Gerbens, L. (Creator) & Spuls, P. (Creator), Taylor & Francis, 2021
DOI: 10.6084/m9.figshare.16418799.v1, https://tandf.figshare.com/articles/dataset/On_which_evidence_can_we_rely_when_prescribing_off-label_methotrexate_in_dermatological_practice_a_systematic_review_with_GRADE_approach/16418799/1
Dataset
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Sex differences in adverse drug reactions from Adalimumab and etanercept in patients with inflammatory rheumatic diseases
Gosselt, H. R. (Creator), van Lint, J. A. (Creator), Kosse, L. J. (Creator), Spuls, P. (Creator), Vonkeman, H. E. (Creator), Tas, S. (Creator), Hoentjen, F. (Creator), Nurmohamed, M. (Creator), van den Bemt, B. J. F. (Creator), van Doorn, M. B. A. (Creator), Jessurun, N. T. (Creator) & van den Bemt, B. J. F. (Creator), Taylor & Francis, 2023
DOI: 10.6084/m9.figshare.22199555, https://tandf.figshare.com/articles/dataset/Sex_differences_in_adverse_drug_reactions_from_Adalimumab_and_etanercept_in_patients_with_inflammatory_rheumatic_diseases/22199555
Dataset
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The clinical relevance of dupilumab serum concentration in patients with atopic dermatitis: a two-center prospective cohort study
Bosma, A. L. (Creator), Gerbens, L. (Creator), El Khattabi, H. (Contributor), Loeff, F. C. (Creator), Duckworth, M. (Creator), Woolf, R. T. (Creator), Rispens, T. (Creator), Smith, C. H. (Creator) & Spuls, P. (Creator), Taylor & Francis, 2023
DOI: 10.6084/m9.figshare.22700620, https://tandf.figshare.com/articles/dataset/The_clinical_relevance_of_dupilumab_serum_concentration_in_patients_with_atopic_dermatitis_a_two-center_prospective_cohort_study/22700620
Dataset
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On which evidence can we rely when prescribing off-label methotrexate in dermatological practice? – a systematic review with GRADE approach
van Huizen, A. (Creator), Vermeulen, F. M. (Creator), Bik, C. M. J. M. (Creator), Borgonjen, R. (Creator), Karsch, S. A. T. (Creator), Kuin, R. A. (Creator), Gerbens, L. (Creator) & Spuls, P. (Creator), Taylor & Francis, 2021
DOI: 10.6084/m9.figshare.16418799.v2, https://tandf.figshare.com/articles/dataset/On_which_evidence_can_we_rely_when_prescribing_off-label_methotrexate_in_dermatological_practice_a_systematic_review_with_GRADE_approach/16418799/2
Dataset
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Sex differences in adverse drug reactions from Adalimumab and etanercept in patients with inflammatory rheumatic diseases
Gosselt, H. R. (Creator), van Lint, J. A. (Creator), Kosse, L. J. (Creator), Spuls, P. (Creator), Vonkeman, H. E. (Creator), Tas, S. (Creator), Hoentjen, F. (Creator), Nurmohamed, M. T. (Creator), van den Bemt, B. J. F. (Creator), van Doorn, M. B. A. (Creator), Jessurun, N. T. (Creator) & van den Bemt, B. J. F. (Creator), Taylor & Francis, 2023
DOI: 10.6084/m9.figshare.22199555, https://tandf.figshare.com/articles/dataset/Sex_differences_in_adverse_drug_reactions_from_Adalimumab_and_etanercept_in_patients_with_inflammatory_rheumatic_diseases/22199555
Dataset