Projects per year
Personal profile
specialisation
Pathology/neuro-oncological pathology
Research interests
- Unraveling the molecular underpinnings of primary tumors of the central nervous system (CNS);
- Translation of these findings in improved clinical diagnosis and classification of CNS tumors;
- Elucidation of the role of the tumor microenvironment in the pathobiology and clinical behavior of CNS tumors.
Pieter Wesseling is a (neuro)pathologist and full professor at the department of Pathology at the Amsterdam UMC, and he is additionally affiliated with the Princess Máxima Center for Pediatric Oncology in Utrecht. Wesseling was trained as clinical (neuro)pathologist in the Radboud University Medical Center in Nijmegen (supervised by Prof. Joop L. Slooff), and in Duke University Medical Center in Durham NC, USA (Prof. Peter C. Burger. He has led multiple (inter)national research projects, (co-)authored more than 300 papers in international, peer-reviewed journals on neuro-oncological topics, is member of the editorial board of several international neuro-oncological and neuropathological journals. He is at present chair of the consortium to Improve Molecular and Practical Approaches for CNS tumor Taxonomy (cIMPACT-NOW) Steering Committee, was centrally involved in shaping the revised 4th edition of the WHO CNS tumor classification (2016) and is an expert editor of the 5th (2021) edition of this classification as well as of the WHO classification of Pediatric Tumors (2022).
Activities
- Expert member of the editorial board of the WHO 2021 Classification of CNS tumors
- Chair of the consortium to Improve Molecular and Practical Approaches to CNS Tumor Taxonomy/cIMPACT-NOW (link)
- Chair of the International Collaboration of Cancer Reporting (Neuropathology branch)
Collaborations and top research areas from the last five years
Projects
- 1 Active
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GLIOCARE
Keil, V., Wamelink, I., Azizova, A., Barkhof, F., Mutsaerts, H., Petr, J., de Witt Hamer, P., Wesseling, P. & Kouwenhoven, M.
1/04/2022 → …
Project: Research
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AllergoOncology: Biomarkers and refined classification for research in the allergy and glioma nexus—A joint EAACI-EANO position paper
Turner, M. C., Radzikowska, U., Ferastraoaru, D. E., Pascal, M., Wesseling, P., McCraw, A., Backes, C., Bax, H. J., Bergmann, C., Bianchini, R., Cari, L., de las Vecillas, L., Izquierdo, E., Lind-Holm Mogensen, F., Michelucci, A., Nazarov, P. V., Niclou, S. P., Nocentini, G., Ollert, M., Preusser, M., & 10 others , Jun 2024, In: Allergy: European Journal of Allergy and Clinical Immunology. 79, 6, p. 1419-1439 21 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Next generation sequencing of high-grade adult-type diffuse glioma in the Netherlands: interlaboratory variation in the primary diagnostic and recurrent setting
van Opijnen, M. P., Broekman, M. L. D., Cuppen, E., Dubbink, H. J., ter Elst, A., van Eijk, R., Mühlebner, A., Jansen, C., van der Geize, R., Speel, E-J. M., Groenen, P. J. T. A., de Vos, F. Y. F., Wesseling, P., de Leng, W. W. J. & Maas, S. L. N., 1 Feb 2024, In: Journal of Neuro-Oncology. 166, 3, p. 485-492 8 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus) -
Protocol for investigating data quality and reporting outcomes of pediatric gliomas in population-based cancer registry research
Hoogendijk, R., van der Lugt, J., Kranendonk, M. E. G., Gatta, G., Capocaccia, R., Hoving, E. W., Wesseling, P., Visser, O., van Vuurden, D. G. & Karim-Kos, H., 15 Mar 2024, In: STAR Protocols. 5, 1, 102905.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus) -
RT-PCR assay to detect FGFR3: :TACC3 fusions in formalin-fixed, paraffin-embedded glioblastoma samples
Priesterbach-Ackley, L. P., van Kuik, J., Tops, B. B. J., Lasorella, A., Iavarone, A., van Hecke, W., Robe, P. A., Wesseling, P. & de Leng, W. W. J., 1 Apr 2024, In: Neuro-Oncology Practice. 11, 2, p. 142-149 8 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus) -
The immunological landscape of peripheral blood in glioblastoma patients and immunological consequences of age and dexamethasone treatment
Dusoswa, S. A., Verhoeff, J., van Asten, S., Lübbers, J., van den Braber, M., Peters, S., Abeln, S., Crommentuijn, M. H. W., Wesseling, P., Vandertop, W. P., Twisk, J. W. R., Würdinger, T., Noske, D., van Kooyk, Y. & Garcia-Vallejo, J. J., 2024, In: Frontiers in immunology. 15, p. 1343484 1343484.Research output: Contribution to journal › Article › Academic › peer-review
Open Access