Projects per year
Personal profile
Research interests
Population pharmacokinetic-pharmacodynamic modeling of antimicrobial drugs: exposure optimisation studies, dose individualisation studies, concentration-effect relationship studies as well as studies into the relationship between drug concentration and the risk for acquiring drug resistance).
Collaboration with the Molecular Biology and Microbial Food Safety research group of the Swammerdam Institute for Life Sciences of the University of Amsterdam (Dr. Benno ter Kuile, PhD)
Collaboaration with the departement of Intensive Care Medicine (Prof. dr. J. Wauters) and the departement of Hospital Pharmacy (Prof. dr. I. Spriet) of the University Hospitals Leuven, Belgium
Population pharmacokinetic-pharmacodynamic modeling of antihypertensive drugs: dose individualisation studies, concentration-effect relationship studies
Clinical pharmacological research of prothrombin complex concentrate (dose optimisation studies).
Collaboration with the department of Haematology of the University Medical Center Groningen (Prof. dr. K. Meijer) and the Central Hospital Pharmacy, The Hague (Dr. N. Khorsand)
Specialisation
Network
Projects
- 1 Active
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Mathôt R.A.A.: Population pharmacokinetic-pharmacodynamic research
Achterbergh, R., Berends, S. E., ten Berg - Lammers, L. A., Bijleveld, Y. A., Hodiamont, C. J., Preijers, T., Wind, C. M., Mathot, R. A. A., Fijnvandraat, K., de Haan, T. R., Kemper, M. M., Klümpen, H., van Hest, R. M., Kuks, P. F. M., Zwaan, C. M., Franken, L., Hazendonk, C., Masman, A., van Moort, I., Sassen, S., Schutte, L. M., Cnossen, M., van Gelder, T., Kruip, M. J. H. A., Leebeek, F. W. G. & Tibboel, D.
1/12/2012 → …
Project: Research
Research output
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An Unusual Case of Low Vancomycin Exposure Despite Extremely High Vancomycin Doses Accompanied by Renal Toxicity: A Grand Round
van Schip, A. M., van Diemen, J. J. K., van Hest, R. M. & Harris, V. C., 2 Jan 2023, (E-pub ahead of print) In: Therapeutic Drug Monitoring.Research output: Contribution to journal › Article › Academic › peer-review
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On the potential for discontinuing atovaquone-proguanil (AP) ad-hoc post-exposure and other abbreviated AP-regimens: Pharmacology, pharmacokinetics and perspectives
Schnyder, J. L., de Jong, H. K., Bache, E. B., van Hest, R. M., Schlagenhauf, P., Borrmann, S., Hanscheid, T. & Grobusch, M. P., 1 Mar 2023, In: Travel Medicine and Infectious Disease. 52, p. 102520 102520.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
ALLERGIELABELS IN OPENBARE APOTHEEK VAAK NIET MEER ACTUEEL
Terreehorst, I., Zwilling, A., Aarts, J., van Hattem, J. & van Hest, R., 18 Nov 2022, In: Pharmaceutisch Weekblad. 157, 46, p. 20-21Research output: Contribution to journal › Article › Professional
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Carbapenems: inzetten als het moet, vermijden als het kan
de Stoppelaar, S. F., ten Oever, J., Wertheim, H. F. L., van Hest, R. M., van Mens, S., van Dijk, K., van Agtmael, M. A. & Wolfs, T. F. W., 17 Oct 2022, In: Nederlands Tijdschrift voor Geneeskunde. 166Translated title of the contribution :Carbapenems: take it when needed but leave it if you can Research output: Contribution to journal › Article › Professional
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Clinical Pharmacokinetics of Gentamicin in Various Patient Populations and Consequences for Optimal Dosing for Gram-Negative Infections: An Updated Review
Hodiamont, C. J., van den Broek, A. K., de Vroom, S. L., Prins, J. M., Mathôt, R. A. A. & van Hest, R. M., 1 Aug 2022, In: Clinical pharmacokinetics. 61, 8, p. 1075-1094 20 p.Research output: Contribution to journal › Review article › Academic › peer-review
Open Access4 Citations (Scopus)