Research output per year
Research output per year
Personal profile
Research interests
Population pharmacokinetic-pharmacodynamic modeling of antimicrobial drugs: exposure optimisation studies, dose individualisation studies, concentration-effect relationship studies as well as studies into the relationship between drug concentration and the risk for acquiring drug resistance).
Collaboration with the Molecular Biology and Microbial Food Safety research group of the Swammerdam Institute for Life Sciences of the University of Amsterdam (Dr. Benno ter Kuile, PhD)
Collaboaration with the departement of Intensive Care Medicine (Prof. dr. J. Wauters) and the departement of Hospital Pharmacy (Prof. dr. I. Spriet) of the University Hospitals Leuven, Belgium
Population pharmacokinetic-pharmacodynamic modeling of antihypertensive drugs: dose individualisation studies, concentration-effect relationship studies
Clinical pharmacological research of prothrombin complex concentrate (dose optimisation studies).
Collaboration with the department of Haematology of the University Medical Center Groningen (Prof. dr. K. Meijer) and the Central Hospital Pharmacy, The Hague (Dr. N. Khorsand)
Specialisation
Clinical Pharmacology
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Pooled Population Pharmacokinetic Analysis for Exploring Ciprofloxacin Pharmacokinetic Variability in Intensive Care Patients
the Dutch Antibiotic PK/PD Collaborators, 2022, (E-pub ahead of print) In: Clinical pharmacokinetics.Research output: Contribution to journal › Article* › Academic › peer-review
Open Access -
Does dose reduction of renally cleared antibiotics in patients with impaired renal function lead to adequate drug exposure? A systematic review
de Vroom, S. L., van Daalen, F. V., Zieck, S. E., Mathôt, R. A. A., van Hest, R. M. & Geerlings, S. E., Mar 2021, In: Clinical microbiology and infection. 27, 3, p. 352-363 12 p.Research output: Contribution to journal › Review article* › Academic › peer-review
Open Access -
Impact of a vancomycin loading dose on the achievement of target vancomycin exposure in the first 24 h and on the accompanying risk of nephrotoxicity in critically ill patients
Hodiamont, C. J., Juffermans, N. P., Berends, S. E., van Vessem, D. J., Hakkens, N., Mathôt, R. A. A., de Jong, M. D. & van Hest, R. M., 1 Nov 2021, In: Journal of antimicrobial chemotherapy. 76, 11, p. 2941-2949 9 p.Research output: Contribution to journal › Article* › Academic › peer-review
Open Access -
Low frequency of community-acquired bacterial co-infection in patients hospitalized for COVID-19 based on clinical, radiological and microbiological criteria: a retrospective cohort study
Coenen, S., de la Court, J. R., Buis, D. T. P., Meijboom, L. J., Schade, R. P., Visser, C. E., van Hest, R., Kuijvenhoven, M., Prins, J. M., Nijman, S. F. M., Sieswerda, E. & Sigaloff, K. C. E., 1 Dec 2021, In: Antimicrobial Resistance and Infection Control. 10, 1, p. 155 155.Research output: Contribution to journal › Article* › Academic › peer-review
Open Access -
Population pharmacokinetics and probability of target attainment of different dosing regimens of ceftazidime in critically ill patients with a proven or suspected pseudomonas aeruginosa infection
Buning, A. W., Hodiamont, C. J., Lechner, N. M., Schokkin, M., Elbers, P. W. G., Juffermans, N. P., Mathôt, R. A. A., de Jong, M. D. & van Hest, R. M., 1 Jun 2021, In: Antibiotics. 10, 6, 612.Research output: Contribution to journal › Article* › Academic › peer-review
Open Access