Projects per year
Personal profile
Research interests
Renee Schreurs is a postdoctoral fellow in the Autophagy-directed Immunity lab headed by dr. Carla Ribeiro at the Department of Experimental Immunology, Amsterdam UMC (location AMC). She holds a MSc in Neuroscience and completed a PhD on the development of mucosal T cell immunity in the early-life intestine.
Within dr. Ribeiro's lab, Renee's current research focuses on investigating the impact of genetic variation in autophagy pathways on T cell functionality in the context of viral infections such as HIV-1. Additionally, Renee studies the impact of autophagy and extracellular vescicles on intestinal barrier integrity and inflammation using advanced organoid and organoid-immune cell co-culture models through partnerships with the Gutvibrations consortium and Emma Children's Hospital.
Ultimately, the Autophagy-directed Immunity lab aims to harness the therapeutic potential of targeting autophagy mechanisms to intervene with HIV-1, Dengue virus, and SARS-CoV-2 infections.
specialisation
T cell immunity, intestinal inflammation, mucosal immune system, cell & organoid culture, autophagy, neuroscience, fetal and pediatric immunity, HIV-1
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 2 Active
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van Goudoever J.B.: Nutrition and Growth
van Goudoever, H., Akkermans, M., An, N., Beukers, F., Colenbrander, A., Gaasterland, C., Gigengack, M., van Ham, K., van Harskamp, D., Ingelse, S., Mank, E., Nieuwenhuijse, M., Oosterink, J., Schoonenboom, J., Schreurs, R., Zaal - Schuller, I., van Veenendaal, N. & Wijngaarde, R.
1/05/2013 → …
Project: Research
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Kuijpers T.W.: Infection and inflammation: on the crossroad of hematology and immunology
Aarts, C., de Back, D., Barendregt, A., van Beek, A., de Blauw, D., Blokhuis, C., Bouva, M., Bruggeman, C., Bruning, A., Dalimot, J., Dietz, S., van de Geer, A., van Gulik, C., Gunnink, S., Keizer, S., Klaassen, I., Meinderts, S., Nagelkerke, S., Pouw, R., van Rees, D., Scheenstra, M., Schonenberg, D., Schreurs, R., Sins, J., Stokhuijzen, E., Treffers, L., Tuijnenburg, P., Kuijpers, T., Boele van Hensbroek, M., Fijnvandraat, K., Pajkrt, D., van Rossum, M. A. J. & Hemke, R.
1/01/2006 → …
Project: Research
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Autophagy-enhancing ATG16L1 polymorphism is associated with improved clinical outcome and T-cell immunity in chronic HIV-1 infection
Schreurs, R. R. C. E., Koulis, A., Booiman, T., Boeser-Nunnink, B., Cloherty, A. P. M., Rader, A. G., Patel, K. S., Kootstra, N. A. & Ribeiro, C. M. S., 1 Dec 2024, In: Nature communications. 15, 1, 2465.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Berbamine suppresses intestinal SARS-CoV-2 infection via a BNIP3-dependent autophagy blockade
Cloherty, A. P. M., Rader, A. G., Patel, K. S., Pérez-Vargas, J., Thompson, C. A. H., Ennis, S., Niikura, M., Wildenberg, M. E., Muncan, V., Schreurs, R. R. C. E., Jean, F. & Ribeiro, C. M. S., 1 Dec 2023, In: Emerging Microbes & Infections. 12, 1, p. 2195020 2195020.Research output: Contribution to journal › Article › Academic › peer-review
Open Access3 Citations (Scopus) -
CXCR5+PD-1++ CD4+ T cells colonize infant intestines early in life and promote B cell maturation
Jordan-Paiz, A., Martrus, G., Steinert, F. L., Kaufmann, M., Sagebiel, A. F., Schreurs, R. R. C. E., Rechtien, A., Baumdick, M. E., Jung, J. M., Möller, K. J., Wegner, L., Grüttner, C., Richert, L., Thünauer, R., Schroeder-Schwarz, J., van Goudoever, J. B., Geijtenbeek, T. B. H., Altfeld, M., Pals, S. T., Perez, D., & 9 others, Feb 2023, In: Cellular & molecular immunology. 20, 2, p. 201-213 13 p.Research output: Contribution to journal › Article › Academic › peer-review
2 Citations (Scopus) -
Enhanced Th17 responses in the appendix of children with complex compared to simple appendicitis are associated with microbial dysbiosis
The, S-M. M. L., Schreurs, R. R. C. E., Drewniak, A., Bakx, R., de Meij, T. G. J., Budding, A. E., Poort, L., Cense, H. A., Heij, H. A., van Heurn, L. W. E., Gorter, R. R. & Bunders, M. J., 2023, In: Frontiers in immunology. 14, p. 1258363 1258363.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Expanded ILC2s in human infant intestines promote tissue growth
Möller, K. J., Wegner, L. H. M., Malsy, J., Baumdick, M. E., Borggrewe, M., Jordan-Paiz, A., Jung, J. M., Martrus, G., Kretschmer, P., Sagebiel, A. F., Schreurs, R. R. C. E., Hagen, S. H., Burmester, G., Clauditz, T. S., Pals, S. T., Boettcher, M., Melling, N., Sauter, G., Tomuschat, C., Königs, I., & 6 others, Aug 2023, In: Mucosal Immunology. 16, 4, p. 408-421 14 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access3 Citations (Scopus)
Datasets
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Berbamine suppresses intestinal SARS-CoV-2 infection via a BNIP3-dependent autophagy blockade
Cloherty, A. (Creator), Rader, A. (Creator), Patel, K. S. (Creator), Pérez-Vargas, J. (Creator), Thompson, C. A. H. (Creator), Ennis, S. (Creator), Niikura, M. (Creator), Wildenberg, M. (Creator), Dijkstra - Muncan, V. (Creator), Schreurs, R. (Creator), Jean, F. (Creator) & Ribeiro, C. (Creator), Taylor & Francis, 2023
DOI: 10.6084/m9.figshare.22323729, https://tandf.figshare.com/articles/dataset/Berbamine_suppresses_intestinal_SARS-CoV-2_infection_via_a_BNIP3-dependent_autophagy_blockade/22323729
Dataset
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Berbamine suppresses intestinal SARS-CoV-2 infection via a BNIP3-dependent autophagy blockade
Cloherty, A. (Creator), Rader, A. (Creator), Patel, K. S. (Creator), Pérez-Vargas, J. (Creator), Thompson, C. A. H. (Creator), Ennis, S. (Creator), Niikura, M. (Creator), Wildenberg, M. (Creator), Dijkstra - Muncan, V. (Creator), Schreurs, R. (Creator), Jean, F. (Creator) & Ribeiro, C. (Creator), Taylor & Francis, 2023
DOI: 10.6084/m9.figshare.22323729.v2, https://tandf.figshare.com/articles/dataset/Berbamine_suppresses_intestinal_SARS-CoV-2_infection_via_a_BNIP3-dependent_autophagy_blockade/22323729/2
Dataset