Richard J. Honeywell

Research output

Research output per year 2007 2009 2010 2012 2013 2014 2015 2016 2018 2019 2020 2021 2022

• 61 Article
• 4 Meeting Abstract
• 2 Comment/Letter to the editor
• 1 Letter
• 1 More
  • 1 Review article

Research output per year

Research output per year

Search results

• 2022

  Radio-sensitizing effect of MEK inhibition in glioblastoma in vitro and in vivo

  Houweling, M., Abdul, U. K., Brahm, C., Lagerweij, T., Heukelom, S., Koken, P. W., Honeywell, R., Wedekind, L. E., Peters, G. J., Verheul, H., Sminia, P., Noske, D., Wurdinger, T. & Westerman, B. A., 2022, (E-pub ahead of print) In: Journal of Cancer Research and Clinical Oncology.

  Research output: Contribution to journal › Article › Academic › peer-review
  5 Citations (Scopus)

• Tumor Drug Concentration and Phosphoproteomic Profiles After Two Weeks of Treatment With Sunitinib in Patients with Newly Diagnosed Glioblastoma

  van Linde, M. E., Labots, M., Brahm, C. G., Hovinga, K. E., de Witt Hamer, P. C., Honeywell, R. J., de Goeij-de Haas, R., Henneman, A. A., Knol, J. C., Peters, G. J., Dekker, H., Piersma, S. R., Pham, T. V., Vandertop, W. P., Jiménez, C. R., Verheul, H. M. W. & van Linde, M. E., 15 Apr 2022, In: Clinical Cancer Research. 28, 8, p. 1595-1602 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  10 Citations (Scopus)
• 2021

  11C-Sorafenib and 15O-H2O PET for Early Evaluation of Sorafenib Therapy

  Mammatas, L. H., Yaqub, M., Hendrikse, N. H., Hoekstra, O. S., Honeywell, R. J., Schuit, R. C., Meijerink, M., Schwarte, L. A., Peters, G. J., Verheul, H. M. W., Lammertsma, A. A. & Menke-van der Houven van Oordt, C. W., 1 Jul 2021, In: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 62, 7, p. 934-940 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review

• Carboplatin dosing in children using estimated glomerular filtration rate: Equation matters

  van de Velde, M. E., den Bakker, E., Blufpand, H. N., Kaspers, G. L., Abbink, F. C. H., Kors, A. W. A., Wilhelm, A. J., Honeywell, R. J., Peters, G. J., Stoffel‐wagner, B., Buffart, L. M. & Bökenkamp, A., 1 Dec 2021, In: Cancers. 13, 23, 5963.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  2 Citations (Scopus)

• Elevated acute phase proteins affect pharmacokinetics in COVID-19 trials: lessons from the CounterCovid - imatinib - study

  Bartelink, I. H., Bet, P. M., Widmer, N., Guidi, M., Duijvelaar, E., Grob, B., Honeywell, R., Evelo, A., Tielbeek, I. P. E., Snape, S. D., Hamer, H., Decosterd, L. A., Bogaard, H. J., Aman, J. & Swart, E. L., Dec 2021, In: CPT: Pharmacometrics and Systems Pharmacology. 10, 12, p. 1497-1511 15 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  7 Citations (Scopus)

• The prognostic impact of circulating miRNAs in patients with advanced esophagogastric cancer during palliative chemotherapy

  van Zweeden, A. A., Opperman, R. C. M., Honeywell, R. J., Peters, G. J., Verheul, H. M. W., van der Vliet, H. J. & Poel, D., 2021, In: Cancer treatment and research communications. 27, 100371.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  4 Citations (Scopus)
• 2020

  Crizotinib sensitizes the erlotinib resistant HCC827GR5 cell line by influencing lysosomal function

  Van Der Steen, N., Keller, K., Dekker, H., Porcelli, L., Honeywell, R. J., Van Meerloo, J., Musters, R. J. P., Kathmann, I., Frampton, A. E., Liu, D. S. K., Ruijtenbeek, R., Rolfo, C., Pauwels, P., Giovannetti, E. & Peters, G. J., 1 Nov 2020, In: Journal of cellular physiology. 235, 11, p. 8085-8097 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  6 Citations (Scopus)

• Epithelial transfer of the tyrosine kinase inhibitors erlotinib, gefitinib, afatinib, crizotinib, sorafenib, sunitinib, and dasatinib: Implications for clinical resistance

  Honeywell, R. J., Kathmann, I., Giovannetti, E., Tibaldi, C., Smit, E. F., Rovithi, M. N., Verheul, H. M. W. & Peters, G. J., 1 Nov 2020, In: Cancers. 12, 11, p. 1-18 18 p., 3322.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  10 Citations (Scopus)

• Kinase Inhibitor Treatment of Patients with Advanced Cancer Results in High Tumor Drug Concentrations and in Specific Alterations of the Tumor Phosphoproteome

  Labots, M., Pham, T. V., Honeywell, R. J., Knol, J. C., Beekhof, R., de Goeij-de Haas, R., Dekker, H., Neerincx, M., Piersma, S. R., van der Mijn, J. C., van der Peet, D. L., Meijerink, M. R., Peters, G. J., van Grieken, N. C. T., Jiménez, C. R. & Verheul, H. M. W., 1 Feb 2020, In: Cancers. 12, 2, 330.

  Research output: Contribution to journal › Article › Academic › peer-review
  11 Citations (Scopus)

• Rx-3117 (Fluorocyclopentenyl-cytosine)-mediated down-regulation of dna methyltransferase 1 leads to protein expression of tumor-suppressor genes and increased functionality of the proton-coupled folate carrier

  Sarkisjan, D., Julsing, J. R., El Hassouni, B., Honeywell, R. J., Kathmann, I., Matherly, L. H., Lee, Y. B., Kim, D. J. & Peters, G. J., Apr 2020, In: International journal of molecular sciences. 21, 8, 2717.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  5 Citations (Scopus)

• Sorafenib administered using a high-dose, pulsatile regimen in patients with advanced solid malignancies: a phase I exposure escalation study

  Mammatas, L. H., Zandvliet, A. S., Rovithi, M., Honeywell, R. J., Swart, E. L., Peters, G. J., Menke-van der Houven van Oordt, C. W. & Verheul, H. M. W., 1 May 2020, In: Cancer Chemotherapy and Pharmacology. 85, 5, p. 931-940 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  8 Citations (Scopus)
• 2019

  Coexisting Molecular Determinants of Acquired Oxaliplatin Resistance in Human Colorectal and Ovarian Cancer Cell Lines

  Noordhuis, P., Laan, A. C., van de Born, K., Honeywell, R. J. & Peters, G. J., 2019, In: International journal of molecular sciences. 20, 15

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  20 Citations (Scopus)

• Phase I Dose-Escalation Study of Once Weekly or Once Every Two Weeks Administration of High-Dose Sunitinib in Patients With Refractory Solid Tumors

  Rovithi, M., Gerritse, S. L., Honeywell, R. J., Ten Tije, A. J., Ruijter, R., Peters, G. J., Voortman, J., Labots, M. & Verheul, H. M. W., 10 Feb 2019, In: Journal of clinical oncology. 37, 5, p. 411-418 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  13 Citations (Scopus)

• RX-3117 (fluorocyclopentenyl cytosine): a novel specific antimetabolite for selective cancer treatment

  Balboni, B., el Hassouni, B., Honeywell, R. J., Sarkisjan, D., Giovannetti, E., Poore, J., Heaton, C., Peterson, C., Benaim, E., Lee, Y. B., Kim, D. J. & Peters, G. J., 3 Apr 2019, In: Expert opinion on investigational drugs. 28, 4, p. 311-322 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  17 Citations (Scopus)
• 2018

  Cytidine deaminase enzymatic activity is a prognostic biomarker in gemcitabine/platinum-treated advanced non-small-cell lung cancer: a prospective validation study

  Italian Oncological Group of Clinical Research (GOIRC) & on behalf of The Italian Oncological Group of Clinical Research (GOIRC), 27 Nov 2018, In: British journal of cancer. 119, 11, p. 1326-1331 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  12 Citations (Scopus)

• DNA methyltransferases expression in normal tissues and various human cancer cell lines, xenografts and tumors.

  Honeywell, R. J., Sarkisjan, D., Kristensen, M. H., de Klerk, D. J. & Peters, G. J., 2 Dec 2018, In: Nucleosides, Nucleotides and Nucleic Acids. 37, 12, p. 696-708 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  18 Citations (Scopus)

• Platelet function is disturbed by the angiogenesis inhibitors sunitinib and sorafenib, but unaffected by bevacizumab

  Walraven, M., Homs, M. Y. V., van der Veldt, A. A. M., Dekker, H., Koldenhof, J., Honeywell, R., Barendrecht, A., Sebastian, S. A. E., Parr, N., Koekman, A. C., Voest, E. E., Roest, M., Korporaal, S. J. A. & Verheul, H. M. W., 2018, In: Angiogenesis. 21, 2, p. 325-334

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  19 Citations (Scopus)

• Randomized phase 2 study of gemcitabine and cisplatin with or without vitamin supplementation in patients with advanced esophagogastric cancer

  van Zweeden, A. A., van Groeningen, C. J., Honeywell, R. J., Giovannetti, E., Ruijter, R., Smorenburg, C. H., Giaccone, G., Verheul, H. M. W., Peters, G. J. & van der Vliet, H. J., Jul 2018, In: Cancer Chemotherapy and Pharmacology. 82, 1, p. 39-48 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  8 Citations (Scopus)

• Subcellular localization of several structurally different tyrosine kinase inhibitors

  Honeywell, R. J., Hitzerd, S. M., Kathmann, G. A. M. & Peters, G. J., 2018, In: ADMET & DMPK. 6, 3, p. 258-266

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  3 Citations (Scopus)
• 2017

  Rapid homogeneous immunoassay to quantify gemcitabine in plasma for therapeutic drug monitoring

  Kozo, D., Ross, M. W., Jarrah, J., Barrett, M., Harney, R. L., Courtney, J. B., Baburina, I., Holleran, J. L., Beumer, J. H., Peters, G. J., Honeywell, R. J. & Salamone, S. J., 1 Jun 2017, In: Therapeutic drug monitoring. 39, 3, p. 235-242 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  4 Citations (Scopus)
• 2016

  Adherence and Patients' Experiences with the Use of Capecitabine in Daily Practice

  Timmers, L., Boons, C. C. L. M., Mangnus, D., Van de Ven, P. M., Van den Berg, P. H., Beeker, A., Swart, E. L., Honeywell, R. J., Peters, G. J., Boven, E. & Hugtenburg, J. G., 21 Sept 2016, In: Frontiers in pharmacology. 7

  Research output: Contribution to journal › Article › Academic › peer-review
  16 Citations (Scopus)

• Alternative scheduling of pulsatile, high dose sunitinib efficiently suppresses tumor growth

  Rovithi, M., de Haas, R. R., Honeywell, R. J., Poel, D., Peters, G. J., Griffioen, A. W. & Verheul, H. M. W., 7 Sept 2016, In: Journal of experimental & clinical cancer research. 35

  Research output: Contribution to journal › Article › Academic › peer-review
  15 Citations (Scopus)

• Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK/Akt/mTOR

  Verbrugge, C., Al, M., Assaraf, Y. G., Kammerer, S., Chandrupatla, D. M. S. H., Honeywell, R. J., Musters, R. P. J., Giovannetti, E., O'Toole, T., Scheffer, G. L., Krige, D., de Gruijl, T. D., Niessen, J., Lems, W. F., Kramer, P. A., Scheper, R. J., Cloos, J., Ossenkoppele, G. J., Peters, G. J. & Jansen, G., 2 Feb 2016, In: Oncotarget. 7, 5, p. 5240-5257

  Research output: Contribution to journal › Article › Academic › peer-review

  24 Citations (Scopus)

• Overcoming crizotinib resistance in ALK-rearranged NSCLC with the second-generation ALK-inhibitor ceritinib

  Muller, I. B., De Langen, A. J., Honeywell, R. J., Giovannetti, E. & Peters, G. J., 1 Feb 2016, In: Expert Review of Anticancer Therapy. 16, 2, p. 147-157

  Research output: Contribution to journal › Article › Academic › peer-review
  37 Citations (Scopus)

• Sensitive liquid chromatography mass spectrometry (LC-MS) assay reveals novel insights on DNA methylation and incorporation of gemcitabine, its metabolite difluorodeoxyuridine, deoxyuridine, and RX-3117 into DNA

  Honeywell, R. J., Sarkisjan, D., Kathmann, I., Kristensen, M. H. & Peters, G. J., 2016, In: Nucleosides, Nucleotides and Nucleic Acids. 35, 10-12, p. 652-662

  Research output: Contribution to journal › Article › Academic › peer-review
  4 Citations (Scopus)

• Tissue distribution of Crizotinib and Gemcitabine combination in a patient-derived orthotopic mouse model of pancreatic cancer

  Honeywell, RJ., Avan, A., Giovannetti, E. & Peters, GJ., 2016, In: ADMET & DMPK. 4, p. 327-334

  Research output: Contribution to journal › Article › Academic › peer-review

  1 Citation (Scopus)

• Transport of six tyrosine kinase inhibitors: active or passive?

  Peters, GJ., Honeywell, RJ., Hilzerd, S. & Kathman, I., 2016, In: ADMET & DMPK. 4, p. 23-34

  Research output: Contribution to journal › Article › Academic › peer-review

  10 Citations (Scopus)
• 2015

  Adaptation of a human gut epithelial model in relation to the assessment of clinical pharmacokinetic parameters for selected tyrosine kinase inhibitors

  Honeywell, R. J., Fatmawati, C., Buddha, M., Hitzerd, S., Kathmann, I. & Peters, G. J., 2015, In: ADMET & DMPK. 3, 1, p. 51-67

  Research output: Contribution to journal › Article › Academic › peer-review
  7 Citations (Scopus)

• Cross-resistance to clinically used tyrosine kinase inhibitors sunitinib, sorafenib and pazopanib

  Gotink, K. J., Rovithi, M. N., de Haas, R. R., Honeywell, R. J., Dekker, H., Poel, D., Azijli, K., Peters, G. J., Broxterman, H. J. & Verheul, H. M. W., 2015, In: Cellular oncology. 38, 2, p. 119-129

  Research output: Contribution to journal › Article › Academic › peer-review
  43 Citations (Scopus)

• Drug transport and metabolism of novel anticancer drugs

  Peters, G. J. & Honeywell, R. J., 2015, In: Expert Opinion on Drug Metabolism and Toxicology. 11, 5, p. 661-663

  Research output: Contribution to journal › Article › Academic › peer-review
  5 Citations (Scopus)

• Inhibition of thymidylate synthase by 2 ',2 '-difluoro-2 '-deoxycytidine (Gemcitabine) and its metabolite 2 ',2 '-difluoro-2 '-deoxyuridine

  Honeywell, R. J., van Haperen, V. W. T. R., Veerman, G., Smid, K. & Peters, G. J., 2015, In: International Journal of Biochemistry & Cell Biology. 60, p. 73-81

  Research output: Contribution to journal › Article › Academic › peer-review
  38 Citations (Scopus)

• Optimal treatment scheduling of ionizing radiation and sunitinib improves the antitumor activity and allows dose reduction

  Kleibeuker, E. A., ten Hooven, M. A., Castricum, K. C., Honeywell, R. J., Griffioen, A. W., Verheul, H. M., Slotman, B. J. & Thijssen, V. L. J. L., 2015, In: Cancer Medicine. 4, 7, p. 1003-1015

  Research output: Contribution to journal › Article › Academic › peer-review
  28 Citations (Scopus)

• Physicochemical properties of novel protein kinase inhibitors in relation to their substrate specificity for drug transporters

  Da Silva, C. G., Honeywell, R. J., Dekker, H. & Peters, G. J., 2015, In: Expert Opinion on Drug Metabolism and Toxicology. 11, 5, p. 703-717

  Research output: Contribution to journal › Article › Academic › peer-review
  24 Citations (Scopus)
• 2014

  Acquired tumor cell resistance to sunitinib causes resistance in a HT-29 human colon cancer xenograft mouse model without affecting sunitinib biodistribution or the tumor microvasculature

  Gotink, K. J., Broxterman, H. J., Honeywell, R. J., Dekker, H., de Haas, R. R., Miles, K. M., Adelaiye, R., Griffioen, A. W., Peters, G. J., Pili, R. & Verheul, H. M. W., 2014, In: Oncoscience. 1, 12, p. 844-853

  Research output: Contribution to journal › Article › Academic › peer-review
  26 Citations (Scopus)

• Overexpression of MRP4 (ABCC4) and MRP5 (ABCC5) confer resistance to the nucleoside analogs cytarabine and troxacitabine, but not gemcitabine

  Adema, A. D., Floor, K., Smid, K., Honeywell, R. J., Scheffer, G. L., Jansen, G. & Peters, G. J., 2014, In: SpringerPlus. 3, 732.

  Research output: Contribution to journal › Article › Academic › peer-review
  22 Citations (Scopus)

• Selection of the Best Blood Compartment to Measure Cytidine Deaminase Activity to Stratify for Optimal Gemcitabine Or Cytarabine Treatment

  Peters, G. J., Honeywell, R. J., Maulandi, M., Giovannetti, E., Losekoot, N., Etienne-Grimaldi, M. C., Milano, G., Serdjebi, C. & Ciccolini, J., 2014, In: Nucleosides, Nucleotides and Nucleic Acids. 33, 4-6, p. 403-412

  Research output: Contribution to journal › Article › Academic › peer-review
  19 Citations (Scopus)

• Synergistic interaction of novel lactate dehydrogenase inhibitors with gemcitabine against pancreatic cancer cells in hypoxia

  Maftouh, M., Avan, A., Sciarrillo, R., Granchi, C., Leon, L. G., Rani, R., Funel, N., Smid, K., Honeywell, R. J., Boggi, U., Minutolo, F., Peters, G. J. & Giovannetti, E., 2014, In: British journal of cancer. 110, 1, p. 172-182

  Research output: Contribution to journal › Article › Academic › peer-review
  135 Citations (Scopus)
• 2013

  Crizotinib Inhibits Metabolic Inactivation of Gemcitabine in c-Met-driven Pancreatic Carcinoma

  Avan, A., Caretti, V., Funel, N., Galvani, E., Maftouh, M., Honeywell, R. J., Lagerweij, T., van Tellingen, O., Campani, D., Fuchs, D., Verheul, H. M., Schuurhuis, G. J., Boggi, U., Peters, G. J., Wurdinger, T. & Giovannetti, E., 2013, In: Cancer research. 73, 22, p. 6745-6756

  Research output: Contribution to journal › Article › Academic › peer-review
  81 Citations (Scopus)

• DNA-Bound Platinum Is the Major Determinant of Cisplatin Sensitivity in Head and Neck Squamous Carcinoma Cells

  de Kemp, S. R., Dalm, S. U., Wijnolts, F. M. J., van den Brink, A., Honeywell, R. J., Peters, G. J., Braakhuis, B. J. M. & Brakenhoff, R. H., 2013, In: PLOS ONE. 8, 4, e61555.

  Research output: Contribution to journal › Article › Academic › peer-review
  34 Citations (Scopus)

• Metabolism, mechanism of action and sensitivity profile of fluorocyclopentenylcytosine (RX-3117; TV-1360)

  Peters, G. J., Smid, K., Vecchi, L., Kathmann, I., Sarkisjan, D., Honeywell, R. J., Losekoot, N., Ohne, O., Orbach, A., Blaugrund, E., Jeong, L. S., Lee, Y. B., Ahn, C. H. & Kim, D. J., 2013, In: Investigational new drugs. 31, 6, p. 1444-1457

  Research output: Contribution to journal › Article › Academic › peer-review
  29 Citations (Scopus)

• Molecular mechanisms and modulation of key pathways underlying the synergistic interaction of sorafenib with erlotinib in non-small-cell-lung cancer (NSCLC) cells

  Giovannetti, E., Labots, M., Dekker, H., Galvani, E., Lind, J. S. W., Sciarrillo, R., Honeywell, R., Smit, E. F., Verheul, H. M. & Peters, G. J., 2013, In: Current pharmaceutical design. 19, 5, p. 927-39 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

• Molecular Mechanisms and Modulation of Key Pathways Underlying the Synergistic Interaction of Sorafenib with Erlotinib in Non-Small-Cell-Lung Cancer (NSCLC) Cells

  Giovannetti, E., Labots, M., Dekker, H., Galvani, E., Lind, J. S. W., Sciarrillo, R., Honeywell, R. J., Smit, E. F., Verheul, H. M. & Peters, G. J., 2013, In: Current pharmaceutical design. 19, 5, p. 927-939

  Research output: Contribution to journal › Article › Academic › peer-review
  31 Citations (Scopus)

• Pemetrexed Induced Thymidylate Synthase Inhibition in Non-Small Cell Lung Cancer Patients: A Pilot Study with 3 '-Deoxy-3 '-[F-18]fluorothymidine Positron Emission Tomography

  Frings, V., van der Veldt, A. A. M., Boellaard, R., Herder, G. J. M., Giovannetti, E., Honeywell, R. J., Peters, G. J., Thunnissen, E., Hoekstra, O. S. & Smit, E. F., 2013, In: PLOS ONE. 8, 5, e63705.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  18 Citations (Scopus)

• Successful Treatment of Renal Cell Carcinoma With Sorafenib After Effective but Hepatotoxic Sunitinib Exposure

  Westgeest, H. M., van Erp, N. P., Honeywell, R. J., Hoekstra, R., Peters, G. J. & Verheul, H. M. W., 2013, In: Journal of clinical oncology. 31, 6, p. E83-E86

  Research output: Contribution to journal › Article › Academic › peer-review
  9 Citations (Scopus)
• 2012

  Correlation of cytidine deaminase polymorphisms and activity with clinical outcome in gemcitabine-/platinum-treated advanced non-small-cell lung cancer patients

  Tibaldi, C., Giovannetti, E., Tiseo, M., Leon, L. G., D'Incecco, A., Losekoot, N., Bartolotti, M., Honeywell, R. J., Cappuzzo, F., Ardizzoni, A. & Peters, G. J., 2012, In: Annals of Oncology. 23, 3, p. 670-677

  Research output: Contribution to journal › Article › Academic › peer-review
  48 Citations (Scopus)

• Metabolism and accumulation of the lipophilic deoxynucleoside analogs elacytarabine and CP-4126

  Adema, A. D., Smid, K., Losekoot, N., Honeywell, R. J., Verheul, H. M. W., Myhren, F., Sandvold, M. & Peters, G. J., 2012, In: Investigational new drugs. 30, 5, p. 1908-1916

  Research output: Contribution to journal › Article › Academic › peer-review
  42 Citations (Scopus)

• Molecular Mechanisms Involved in the Synergistic Interaction of the EZH2 Inhibitor 3-Deazaneplanocin A with Gemcitabine in Pancreatic Cancer Cells

  Avan, A., Crea, F., Paolicchi, E., Funel, N., Galvani, E., Marquez, V. E., Honeywell, R. J., Danesi, R., Peters, G. J. & Giovannetti, E., 2012, In: Molecular Cancer Therapeutics. 11, 8, p. 1735-1746

  Research output: Contribution to journal › Article › Academic › peer-review
  84 Citations (Scopus)
• 2011

  Cellular pharmacology of multi- and duplex drugsconsisting of ethynylcytidine and 5-fluoro-2 '-deoxyuridine

  Bijnsdorp, I. V., Schwendener, R. A., Schott, H., Fichtner, I., Smid, K., Laan, A. C., Schott, S., Losekoot, N., Honeywell, R. J. & Peters, G. J., 2011, In: Investigational new drugs. 29, 2, p. 248-257

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  12 Citations (Scopus)

• Determination of the Phosphorylated Metabolites of Gemcitabine and of Difluorodeoxyuridine by Lcmsms

  Honeywell, R. J., Giovannetti, E. & Peters, G. J., 2011, In: Nucleosides, Nucleotides and Nucleic Acids. 30, 12, p. 1203-1213

  Research output: Contribution to journal › Article › Academic › peer-review
  10 Citations (Scopus)

• Lysosomal sequestration of sunitinib: a novel mechanism of drug resistance

  Gotink, K. J., Broxterman, H. J., Labots, M., de Haas, R. R., Dekker, H., Honeywell, R. J., Rudek, M. A., Beerepoot, L. V., Musters, R. J. P., Jansen, G., Griffioen, A. W., Assaraf, Y. G., Pili, R., Peters, G. J. & Verheul, H. M. W., 2011, In: Clinical Cancer Research. 17, 23, p. 7337-7346

  Research output: Contribution to journal › Article › Academic › peer-review
  268 Citations (Scopus)