Projects per year
Personal profile
Research interests
Techniques:
- Population pharmacokinetics and pharmacodynamics (population PK-PD modelling)
- Therapeutic drug monitoring
- Analytical chemistry
- Therapeutic drug monitoring
- Analytical chemistry
Therapeutic fields:
- Blood clotting factor concentrates
- Monoclonal antibodies in inflammatory disease
- Neonatal/pediatric drug therapy
- Antibiotics
specialisation
Clinical Pharmacology
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 1 Active
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Mathôt R.A.A.: Population pharmacokinetic-pharmacodynamic research
Achterbergh, R., Berends, S., ten Berg - Lammers, L., Bijleveld, Y., Hodiamont, C., Preijers, T., Wind, C., Mathot, R., Fijnvandraat, K., de Haan, T., Kemper, M., Klumpen, H., van Hest, R., Kuks, P., Zwaan, C. M., Franken, L., Hazendonk, C., Masman, A., van Moort, I., Sassen, S., Schutte, L. M., Cnossen, M., van Gelder, T., Kruip, M. J. H. A., Leebeek, F. W. G. & Tibboel, D.
1/12/2012 → …
Project: Research
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Evaluation of a System-specific Function to Describe the Pharmacokinetics of Benzylpenicillin in Term Neonates Undergoing Moderate Hypothermia
Bijleveld, Y. A., de Haan, T. R., van der Lee, J. H., Groenendaal, F., Dijk, P. H., van Heijst, A., de Jonge, R. C. J., Dijkman, K. P., van Straaten, H. L. M., Rijken, M., Zonnenberg, I. A., Cools, F., Zecic, A., Nuytemans, D. H. G. M., van Kaam, A. H. & Mathôt, R. A. A., Apr 2018, In: Antimicrobial Agents and Chemotherapy. 62, 4, p. e02311-17Research output: Contribution to journal › Article › Academic › peer-review
Open Access8 Citations (Scopus) -
Pharmacokinetic Modelling to Predict FVIII:C Response to Desmopressin and Its Reproducibility in Nonsevere Haemophilia A Patients
Schütte, L. M., van Hest, R. M., Stoof, S. C. M., Leebeek, F. W. G., Cnossen, M. H., Kruip, M. J. H. A. & Mathôt, R. A. A., 2018, In: Thrombosis and haemostasis. 118, 04, p. 621-629Research output: Contribution to journal › Article › Academic › peer-review
8 Citations (Scopus) -
Effect of Short-Term Fasting on Systemic Cytochrome P450-Mediated Drug Metabolism in Healthy Subjects: A Randomized, Controlled, Crossover Study Using a Cocktail Approach
Lammers, L. A., Achterbergh, R., van Schaik, R. H. N., Romijn, J. A. & Mathôt, R. A. A., 2017, In: Clinical Pharmacokinetics. 56, 10, p. 1231-1244Research output: Contribution to journal › Article › Academic › peer-review
18 Citations (Scopus) -
A population pharmacokinetic model for perioperative dosing of factor VIII in hemophilia A patients
Hazendonk, H., Fijnvandraat, K., Lock, J., Driessens, M., van der Meer, F., Meijer, K., Kruip, M., Gorkom, B. L., Peters, M., de Wildt, S., Leebeek, F., Cnossen, M. & Mathôt, R., 2016, In: Haematologica. 101, 10, p. 1159-1169Research output: Contribution to journal › Article › Academic › peer-review
38 Citations (Scopus) -
Pharmacokinetics of Morphine, Morphine-3-Glucuronide and Morphine-6-Glucuronide in Terminally Ill Adult Patients
Franken, L. G., Masman, A. D., de Winter, B. C. M., Koch, B. C. P., Baar, F. P. M., Tibboel, D., van Gelder, T. & Mathot, R. A. A., 2016, In: Clinical Pharmacokinetics. 55, 6, p. 697-709Research output: Contribution to journal › Article › Academic › peer-review
19 Citations (Scopus)