Projects per year
Collaborations and top research areas from the last five years
Projects
- 3 Finished
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Flash activation of Action potential-independent Neuro Transmission (FAINT): a clinically applicable tool for functional analysis of synaptic disease genes.
Toonen, R. & Groffen, S.
1/07/2013 → 1/07/2017
Project: Research
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Rasal1 regulates calcium dependent neuronal maturation by modifying microtubule dynamics
Deurloo, M. H. S., Eide, S., Turlova, E., Li, Q., Spijker, S., Sun, H. S., Groffen, A. J. A. & Feng, Z. P., 21 Jan 2024, In: Cell and Bioscience. 14, p. 1-20 20 p., 13.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Tomosyns attenuate SNARE assembly and synaptic depression by binding to VAMP2-containing template complexes
Meijer, M., Öttl, M., Yang, J., Subkhangulova, A., Kumar, A., Feng, Z., van Voorst, T. W., Groffen, A. J., van Weering, J. R. T., Zhang, Y. & Verhage, M., 1 Dec 2024, In: Nature communications. 15, 1, p. 1-20 20 p., 2652.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Tomosyn affects dense core vesicle composition but not exocytosis in mammalian neurons
Subkhangulova, A., Gonzalez-Lozano, M. A., Groffen, A. J. A., van Weering, J. R. T., Smit, A. B., Toonen, R. F. & Verhage, M., 11 Sept 2023, In: eLife. 12, p. 1-30 30 p., e85561.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus) -
Ca2+ sensor proteins in spontaneous release and synaptic plasticity: Limited contribution of Doc2c, rabphilin-3a and synaptotagmin 7 in hippocampal glutamatergic neurons
Bourgeois-Jaarsma, Q., Miaja Hernandez, P. & Groffen, A. J., 1 Apr 2021, In: Molecular and Cellular Neuroscience. 112, 103613.Research output: Contribution to journal › Article › Academic › peer-review
Open Access5 Citations (Scopus) -
Doc2 proteins are not required for the increased spontaneous release rate in synaptotagmin-1-deficient neurons
Díez-Arazola, R., Meijer, M., Bourgeois-Jaarsma, Q., Niels Cornelisse, L., Verhage, M. & Groffen, A. J., 25 Mar 2020, In: Journal of neuroscience. 40, 13, p. 2606-2617 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access6 Citations (Scopus)
Datasets
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Tomosyn associates with secretory vesicles in neurons through its N- and C-terminal domains
Groffen, S. (Creator), Geerts, C. J. (Creator) & Mancini, R. (Creator), PLOS, 31 Dec 2017
https://dataverse.nl/dataset.xhtml?persistentId=hdl:10411/Y4R7GN
Dataset
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Replication data for: SICT: automated detection and supervised inspection of fast Ca2+ transients
Groffen, S. (Contributor), Unknown Publisher, 1 Jan 2018
DOI: 10.34894/ywgtjn, https://doi.org/10.34894%2Fywgtjn
Dataset