Projects per year
Susanne de Rooij is a biological psychologist and epidemiologist who is fascinated by how much early life experiences can shape the brain and leave marks with effects into old age. Her studies on men and women who had been prenatally exposed to the Dutch famine showed for the first time that prenatal undernutrition seems to accelerate cognitive aging and affects the size and function of the brain in older age. She also found that applying cognitive behavioural therapy in mothers suffering from depression in pregnancy seemed to induce small changes in the brains of the offspring and in epigenetics.
Dr. de Rooij’s current research work is focused on ‘A healthy brain throughout lifespan’, with the subtopics brain development, cognition, mental health and brain aging. She is leading a number of different projects aiming to further the understanding of the consequences of adverse circumstances during early life for development of the brain and how this affects cognitive and mental health across the lifespan.
Over the years, she has gained interdisciplinary expertise in the fields of biological psychology, epidemiology, and neurobiology and vast experience in project management of large cohort studies as well as smaller neurobiological studies including subjects of all ages. She also has a very active collaboration with the research group from Dr. Aniko Korosi at the Swammerdam Institute of the UvA, aiming to synthesize evidence from animal and human work on the early life origins of metabolic and mental health / dementia.
Epidemiology; Developmental Origins of Health and Disease; Early life stress; Mental and cognitive health; Brain development and aging
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Collaborations and top research areas from the last five years
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Bleker, L., van Dammen, L., van Elten, T., Grooten, I., Karsten, M., Koot, M., Menting, M., Mintjens, S., Oostvogels, A., Pontesilli, M., de Ruigh, A., Wekker, V., Roseboom, T., Painter, R., van de Beek, C., de Rooij, S., Oostvogels, A. & Bosch, H.
1/07/2007 → …
de Rooij, S. R., 16 Jun 2022, In: Frontiers in neuroscience. 16, 825811.
Research output: Contribution to journal › Review article › Academic › peer-reviewOpen Access8 Citations (Scopus)
de Rooij, S. R., Caan, M. W. A., Swaab, D. F., Nederveen, A. J., Majoie, C. B., Schwab, M., Painter, R. C. & Roseboom, T. J., Aug 2016, In: Brain. 139, Part 8, p. 2136-2142 7 p.
Research output: Contribution to journal › Article › Academic › peer-review45 Citations (Scopus)
de Rooij, S. R., Wouters, H., Yonker, J. E., Painter, R. C. & Roseboom, T. J., 2010, In: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 107, 39, p. 16881-16886
Research output: Contribution to journal › Article › Academic › peer-review234 Citations (Scopus)
Prenatal stress and models explaining risk for psychopathology revisited: Generic vulnerability and divergent pathwaysHuizink, A. C. & De Rooij, S. R., Aug 2018, In: Development and psychopathology. 30, SI 3, p. 1041-1062 22 p.
Research output: Contribution to journal › Article › Academic › peer-reviewOpen Access32 Citations (Scopus)
Exploring the effect of antenatal depression treatment on children's epigenetic profiles: Findings from a pilot randomized controlled trialBleker, L. S., Milgrom, J., Sexton-Oates, A., Roseboom, T. J., Gemmill, A. W., Holt, C. J., Saffery, R., Burger, H. & de Rooij, S. R., 2019, In: Clinical epigenetics. 11, 1, 18.
Research output: Contribution to journal › Article › Academic › peer-reviewOpen Access9 Citations (Scopus)