Teunis B. H. Geijtenbeek

(Principal Investigator), Prof. PhD

1992 …2022

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Personal profile

Research interests

We investigate  how pathogens and in particular viruses (HIV-1, SARS-CoV-2, Zika and Dengue virus) infect humans. We thereby study mucosal dendritic cells that function as sentinels that sense invading pathogens and induce appropriate immune responses. However, specific viruses hijack the dendritic cells to establish dissemination throughout the body. Thus, dendritic cells are important in determining the susceptibility of humans to viruses such as HIV-1 and SARS-CoV-2. We use primary human dendritic cells isolated from skin and mucosal tissues and we have also developed different ex vivo human tissue infection models to investigate virus susceptibility in a physiological relevant model. We aim to identify the molecular mechanisms triggered by the pathogens to infiltrate the body via dendritic cells and this will provide novel targets to counteract infections or induce specific immune responses.

Specialisation

Immunology

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

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