Projects per year
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 1 Active
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van Noesel C.J.M.: B cell biology and the pathogenesis of B-NHL/ The serrated neoplasia pathway to colorectal cancer
Bahjat, M., Bloedjes, T., Donner, D., Janssen, J., Mackovicova, K., Slot, L., van Noesel, C., Guikema, J., Bende, R. & ten Hoonte - Wormhoudt, T.
1/10/2006 → …
Project: Research
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AKT supports the metabolic fitness of multiple myeloma cells by restricting FOXO activity
Bloedjes, T. A., de Wilde, G., Khan, G. H., Ashby, T. C., Shaughnessy, J. D., Zhan, F., Houtkooper, R. H., Bende, R. J., van Noesel, C. J. M., Spaargaren, M. & Guikema, J. E. J., 9 May 2023, In: Blood advances. 7, 9, p. 1697-1712 16 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access4 Citations (Scopus) -
SMG1, a nonsense-mediated mRNA decay (NMD) regulator, as a candidate therapeutic target in multiple myeloma
Leeksma, A. C., Derks, I. A. M., Garrick, B., Jongejan, A., Colombo, M., Bloedjes, T., Trowe, T., Leisten, J. C., Howarth, M., Malek, M., Mortensen, D. S., Blease, K., Groza, M. C., Narla, R. K., Loos, R., Kersten, M-J., Moerland, P. D., Guikema, J. E. J., Kater, A. P., Eldering, E., & 1 others, 18 Nov 2022, (E-pub ahead of print) In: Molecular Oncology.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus) -
Metabolic effects of recurrent genetic aberrations in multiple myeloma
Bloedjes, T. A., de Wilde, G. & Guikema, J. E. J., 1 Feb 2021, In: Cancers. 13, 3, p. 1-36 36 p., 396.Research output: Contribution to journal › Review article › Academic › peer-review
Open Access18 Citations (Scopus) -
AKT signaling restrains tumor suppressive functions of FOXO transcription factors and GSK3 kinase in multiple myeloma
Bloedjes, T. A., de Wilde, G., Maas, C., Eldering, E., Bende, R. J., van Noesel, C. J. M., Pals, S. T., Spaargaren, M. & Guikema, J. E. J., 8 Sept 2020, In: Blood advances. 4, 17, p. 4151-4164Research output: Contribution to journal › Article › Academic › peer-review
Open Access18 Citations (Scopus) -
The NEDD8-activating enzyme inhibitor MLN4924 induces DNA damage in Ph+ leukemia and sensitizes for ABL kinase inhibitors
Bahjat, M., de Wilde, G., van Dam, T., Maas, C., Bloedjes, T., Bende, R. J., van Noesel, C. J. M., Luijks, D. M., Eldering, E., Kersten, M. J. & Guikema, J. E. J., 1 Jan 2019, In: Cell Cycle. 18, 18, p. 2307-2322 16 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access9 Citations (Scopus)
Datasets
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The NEDD8-activating enzyme inhibitor MLN4924 induces DNA damage in Ph+ leukemia and sensitizes for ABL kinase inhibitors
Bahjat, M. (Creator), de Wilde, G. (Creator), van Dam, T. (Creator), Maas, C. (Creator), Bloedjes, T. (Creator), Bende, R. (Creator), van Noesel, C. (Creator), Luijks, D. M. (Creator), Eldering, E. (Creator), Kersten, M. J. (Creator) & Guikema, J. (Creator), Taylor & Francis, 2019
DOI: 10.6084/m9.figshare.9119459.v2, https://tandf.figshare.com/articles/dataset/The_NEDD8-activating_enzyme_inhibitor_MLN4924_induces_DNA_damage_in_Ph_leukemia_and_sensitizes_for_ABL_kinase_inhibitors/9119459/2
Dataset
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The NEDD8-activating enzyme inhibitor MLN4924 induces DNA damage in Ph+ leukemia and sensitizes for ABL kinase inhibitors
Bahjat, M. (Creator), de Wilde, G. (Creator), van Dam, T. (Creator), Maas, C. (Creator), Bloedjes, T. (Creator), Bende, R. (Creator), van Noesel, C. (Creator), Luijks, D. M. (Creator), Eldering, E. (Creator), Kersten, M. J. (Creator) & Guikema, J. (Creator), Taylor & Francis, 2019
DOI: 10.6084/m9.figshare.9119459, https://tandf.figshare.com/articles/dataset/The_NEDD8-activating_enzyme_inhibitor_MLN4924_induces_DNA_damage_in_Ph_leukemia_and_sensitizes_for_ABL_kinase_inhibitors/9119459
Dataset
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The NEDD8-activating enzyme inhibitor MLN4924 induces DNA damage in Ph+ leukemia and sensitizes for ABL kinase inhibitors
Bahjat, M. (Creator), de Wilde, G. (Creator), van Dam, T. (Creator), Maas, C. (Creator), Bloedjes, T. (Creator), Bende, R. (Creator), van Noesel, C. (Creator), Luijks, D. M. (Creator), Eldering, E. (Creator), Kersten, M. J. (Contributor), Guikema, J. (Creator) & José Kersten, M. (Creator), Taylor & Francis, 2019
DOI: 10.6084/m9.figshare.9119459.v1, https://tandf.figshare.com/articles/dataset/The_NEDD8-activating_enzyme_inhibitor_MLN4924_induces_DNA_damage_in_Ph_leukemia_and_sensitizes_for_ABL_kinase_inhibitors/9119459/1
Dataset