Research output per year
Research output per year
Personal profile
Research interests
Interested in the interplay between the immune system and viruses, with a focus on B cells and antibodies in relation to HIV-1, SARS-CoV-2 (COVID-19) and influenza.
- It's time for an HIV-1 vaccine - germline targeting as a strategy to induce broadly neutralizing antibodies
- Identifying potent neutralizing antibodies that can prevent severe COVID-19
- Mechanistic understanding of B cells, antibodies and usage of B cell receptors in viral infections
specialisation
B cells, HIV-1, COVID-19, antibodies, protein design, vaccine design
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
- 24 Article
-
Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions
Caniels, T. G., Medina-Ramírez, M., Zhang, J., Sarkar, A., Kumar, S., LaBranche, A., Derking, R., Allen, J. D., Snitselaar, J. L., Capella-Pujol, J., Sánchez, I. D. M., Yasmeen, A., Diaz, M., Aldon, Y., Bijl, T. P. L., Venkatayogi, S., Martin Beem, J. S., Newman, A., Jiang, C., Lee, W-H., & 18 others, 18 Apr 2023, In: Cell Reports Medicine. 4, 4, 101003.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus) -
Identification of new drugs to counteract anti-spike IgG-induced hyperinflammation in severe COVID-19
Amsterdam UMC Covid-19 Biobank, 1 Nov 2023, In: Life Science Alliance. 6, 11Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
SARS-CoV-2 Spike N-Terminal Domain Engages 9-O-Acetylated α2-8-Linked Sialic Acids
Tomris, I., Unione, L., Nguyen, L., Zaree, P., Bouwman, K. M., Liu, L., Li, Z., Fok, J. A., Ríos Carrasco, M., van der Woude, R., Kimpel, A. L. M., Linthorst, M. W., Kilavuzoglu, S. E., Verpalen, E. C. J. M., Caniels, T. G., Sanders, R. W., Heesters, B. A., Pieters, R. J., Jiménez-Barbero, J., Klassen, J. S., & 2 others, 19 May 2023, In: ACS Chemical Biology. 18, 5, p. 1180-1191 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Understanding repertoire sequencing data through a multiscale computational model of the germinal center
García-Valiente, R., Merino Tejero, E., Stratigopoulou, M., Balashova, D., Jongejan, A., Lashgari, D., Pélissier, A., Caniels, T. G., Claireaux, M. A. F., Musters, A., van Gils, M. J., Rodríguez Martínez, M., de Vries, N., Meyer-Hermann, M., Guikema, J. E. J., Hoefsloot, H. & van Kampen, A. H. C., 1 Dec 2023, In: Npj Systems Biology and Applications. 9, 1, 8.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Antibody responses against SARS-CoV-2 variants induced by four different SARS-CoV-2 vaccines in health care workers in the Netherlands: A prospective cohort study
van Gils, M. J., Lavell, A., van der Straten, K., Appelman, B., Bontjer, I., Poniman, M., Burger, J. A., Oomen, M., Bouhuijs, J. H., van Vught, L. A., Slim, M. A., Schinkel, M., Wynberg, E., van Willigen, H. D. G., Grobben, M., Tejjani, K., van Rijswijk, J., Snitselaar, J. L., Caniels, T. G., Vlaar, A. P. J., & 6 others, 1 May 2022, In: PLoS medicine. 19, 5, e1003991.Research output: Contribution to journal › Article › Academic › peer-review
Open Access41 Citations (Scopus)