Research output per year
Research output per year
Personal profile
Research interests
The focus of my research lies on the Second European Carotid Surgery Trial (ECST-2). The ECST-2 is a study in which we randomize between using only optimized medical treatment (OMT) or OMT combined with carotid revascularization (CEA) in patients who suffered stroke due to a plaque in the internal carotid artery. My field of interest will be the clinical outcome in Dutch patients, but with a focus on the cost-effectiveness of the CEA.
Furthermore I am interested in the role of inflammation in carotid plaques and in new MRI techniques that might be better in predicting future stroke in patients with an internal carotid artery plaque.
specialisation
Vascular neurology, with a special focus on the carotid artery and ischemic stroke
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Carotid stenosis: Novel insights in treatment, pathophysiology and costs
van Velzen, T. J., 2024, 195 p.Research output: PhD Thesis › Phd-Thesis - Research and graduation internal
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Application of mask images of contrast-enhanced MR angiography to detect carotid intraplaque hemorrhage in patients with moderate to severe symptomatic and asymptomatic carotid stenosis
Kassem, M., de Kam, S. S., van Velzen, T. J., van der Geest, R., Wagner, B., Sokolska, M., Pizzini, F. B., Nederkoorn, P. J., Rolf Jäger, H., Brown, M. M., van Oostenbrugge, R. J., Bonati, L. H. & Eline Kooi, M., 1 Nov 2023, In: European Journal of Radiology. 168, 111145.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus) -
Association between plaque vulnerability and neutrophil extracellular traps (NETs) levels: The Plaque At RISK study
de Vries, J. J., Autar, A. S. A., van Dam-Nolen, D. H. K., Donkel, S. J., Kassem, M., van der Kolk, A. G., van Velzen, T. J., Kooi, M. E., Hendrikse, J., Nederkoorn, P. J., Bos, D., van der Lugt, A., de Maat, M. P. M. & van Beusekom, H. M. M., 1 Jun 2022, In: PLOS ONE. 17, 6 June, e0269805.Research output: Contribution to journal › Article › Academic › peer-review
Open Access6 Citations (Scopus) -
Leukocyte Count Predicts Carotid Artery Stenosis in Men with Ischemic Stroke: Sub Study of the Preventive Antibiotics in Stroke Study (PASS)
van Velzen, T. J., Stolp, J., Westendorp, W. F., Roos, Y. B. W. E. M., van de Beek, D. & Nederkoorn, P. J., 8 Dec 2022, In: Journal of clinical medicine. 11, 24, 7286.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus) -
The 2nd European Carotid Surgery Trial (ECST-2): rationale and protocol for a randomised clinical trial comparing immediate revascularisation versus optimised medical therapy alone in patients with symptomatic and asymptomatic carotid stenosis at low to intermediate risk of stroke
Cheng, S. F., van Velzen, T. J., Gregson, J., Richards, T., Jäger, H. R., Simister, R., Kooi, M. E., de Borst, G. J., Pizzini, F. B., Nederkoorn, P. J., Brown, M. M. & Bonati, L. H., 1 Dec 2022, In: Trials. 23, 1, 606.Research output: Contribution to journal › Article › Academic › peer-review
Open Access14 Citations (Scopus)