Research output per year
Research output per year
Personal profile
Research interests
Veerle Coupé is associate professor medical decision making, with a focus on optimization and personalization of oncological care and prevention. She leads the research group decision modeling and healthcare evaluation of the Department of Epidemiology and Data Science and is chair of the Decision Modeling Center Amsterdam. Veerle is astronomer by training, with an MSc degree in clinical epidemiology and a PhD degree in medical informatics. She combines her mathematical and epidemiological background in a range of multidisciplinary projects where modelling is used to link data sources and integrate biological and clinical information. These disease models are used to evaluate the health-economic potential of new technologies and to support medical decision making
Her current research work, funded through various grants, including the Netherlands Organisation for Health Research & Development (ZonMw), the Dutch Cancer Society (KWF), and Stand Up To Cancer (SU2C) includes:
- Modelling the effectiveness and cost-effectiveness of colorectal cancer prevention and surveillance.
- Assessment of the impact of the COVID-19 pandemic on colorectal cancer screening outcomes and identification of optimal mitigation strategies
- Personalization of adjuvant treatment allocation and follow-up after treatment for early-stage colorectal cancer
- Health technology assessment for different application of testing for circulating tumour DNA in both lung and colorectal cancer
- Development and evaluation of statistical methods to estimate the duration to cancer progression
- The evaluation of strategies to personalize and optimize lung cancer treatment and surveillance.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Exploring the Cost Effectiveness of a Whole-Genome Sequencing-Based Biomarker for Treatment Selection in Patients with Advanced Lung Cancer Ineligible for Targeted Therapy
Mfumbilwa, Z. A., Simons, M. J. H. G., Ramaekers, B., Retèl, V. P., Mankor, J. M., Groen, H. J. M., Aerts, J. G. J. V., Joore, M., Wilschut, J. A. & Coupé, V. M. H., Apr 2024, In: PharmacoEconomics. 42, 4, p. 419-434 16 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus) -
Polyketide synthase positive Escherichia coli one-time measurement in stool is not informative of colorectal cancer risk in a screening setting
de Klaver, W., de Wit, M., Bolijn, A., Tijssen, M., Delis-van Diemen, P., Lemmens, M., Spaander, M. C. W., Dekker, E., van Leerdam, M. E., Coupé, V. M. H., van Boxtel, R., Clevers, H., Carvalho, B. & Meijer, G. A., Jun 2024, In: Journal of pathology. 263, 2, p. 217-225 9 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
The multitarget faecal immunochemical test for improving stool-based colorectal cancer screening programmes: a Dutch population-based, paired-design, intervention study
Wisse, P. H. A., de Klaver, W., van Wifferen, F., van Maaren-Meijer, F. G., van Ingen, H. E., Meiqari, L., Huitink, I., Bierkens, M., Lemmens, M., Greuter, M. J. E., van Leerdam, M. E., Spaander, M. C. W., Dekker, E., Coupé, V. M. H., Carvalho, B., de Wit, M. & Meijer, G. A., 1 Mar 2024, In: The Lancet Oncology. 25, 3, p. 326-337 12 p.Research output: Contribution to journal › Article › Academic › peer-review
2 Citations (Scopus) -
A BAYESIAN ACCELERATED FAILURE TIME MODEL FOR INTERVAL CENSORED THREE-STATE SCREENING OUTCOMES
Klausch, T., Akwiwu, E. U., VAN DE WIEL, M. A., Coupé, V. M. H. & Berkhof, J., 2023, In: Annals of Applied Statistics. 17, 2, p. 1285-1306 22 p.Research output: Contribution to journal › Article › Academic › peer-review
1 Citation (Scopus) -
A Guide to an Iterative Approach to Model-Based Decision Making in Health and Medicine: An Iterative Decision-Making Framework
Kunst, N., Burger, E. A., Coupé, V. M. H., Kuntz, K. M. & Aas, E., 2023, (E-pub ahead of print) In: PharmacoEconomics.Research output: Contribution to journal › Article › Academic › peer-review
2 Citations (Scopus)
Activities
- 1 Oral presentation
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Versican and vascular endothelial growth factor expression levels in peritoneal metastases from colorectal cancer are associated with survival after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
NR Sluiter (Speaker), EMV de Cuba (Speaker), R Kwakman (Speaker), VMH Coupé (Speaker), JAM Belien (Speaker), GA Meijer (Speaker) & EA te Velde (Speaker)
Mar 2017Activity: Lecture / Presentation › Oral presentation › Academic