Projects per year
Personal profile
Research interests
Perform fundamental and clinical research to develop therapeutics that can reduce vessel wall degradation and thus decrease the growth (rate) and/or rupture risk of aortic aneurysms.
Specialisation
Marfan Syndrome, aortic aneurysm development
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 1 Active
-
de Vries C.J.M.: Nuclear Receptor Nur77 in Vascular Biology and Metabolism
Bossuyt, S. N. V., van Capelleveen, J. C., Jongkind, R. C., Koenis, D. S., van Loon, N. M., Malinova, T., Medzikovic, L., Otermin Rubio, I., van der Stoel, M. M., Tan, J. M. E., Tran, M. K., Wanga, S. A., de Vries, C. J., Huveneers, S., de Waard, V., Arkenbout, E. K., van Loenen, P. B. & Vos, M.
1/02/2007 → …
Project: Research
-
Resveratrol Inhibits Aortic Root Dilatation in the Fbn1C1039G/+ Marfan Mouse Model
Hibender, S., Franken, R., van Roomen, C., ter Braake, A., van der Made, I., Schermer, E. E., Gunst, Q., van den Hoff, M. J., Lutgens, E., Pinto, Y. M., Groenink, M., Zwinderman, A. H., Mulder, B. J. M., de Vries, C. J. M. & de Waard, V., 2016, In: Arteriosclerosis, thrombosis, and vascular biology. 36, 8, p. 1618-1626Research output: Contribution to journal › Article › Academic › peer-review
32 Citations (Scopus) -
Orphan nuclear receptor Nur77 affects cardiomyocyte calcium homeostasis and adverse cardiac remodelling
Medzikovic, L., Schumacher, C. A., Verkerk, A. O., van Deel, E. D., Wolswinkel, R., van der Made, I., Bleeker, N., Cakici, D., van den Hoogenhof, M. M. G., Meggouh, F., Creemers, E. E., Remme, C. A., Baartscheer, A., de Winter, R. J., de Vries, C. J. M., Arkenbout, E. K. & de Waard, V., 2015, In: Scientific reports. 5, p. 15404Research output: Contribution to journal › Article › Academic › peer-review
26 Citations (Scopus) -
Beneficial Outcome of Losartan Therapy Depends on Type of FBN1 Mutation in Marfan Syndrome
Franken, R., den Hartog, A. W., Radonic, T., Micha, D., Maugeri, A., van Dijk, F. S., Meijers-Heijboer, H. E., Timmermans, J., Scholte, A. J., van den Berg, M. P., Groenink, M., Mulder, B. J. M., Zwinderman, A. H., de Waard, V. & Pals, G., 2015, In: Circulation. Cardiovascular genetics. 8, 2, p. 383-388Research output: Contribution to journal › Article › Academic › peer-review
117 Citations (Scopus) -
Losartan reduces aortic dilatation rate in adults with Marfan syndrome: a randomized controlled trial
Groenink, M., den Hartog, A. W., Franken, R., Radonic, T., de Waard, V., Timmermans, J., Scholte, A. J., van den Berg, M. P., Spijkerboer, A. M., Marquering, H. A., Zwinderman, A. H. & Mulder, B. J. M., 2013, In: European Heart journal. 34, 45, p. 3491-3500Research output: Contribution to journal › Article › Academic › peer-review
277 Citations (Scopus) -
Immunosuppressive drug azathioprine reduces aneurysm progression through inhibition of Rac1 and c-Jun-terminal-N-kinase in endothelial cells
Marinkovic, G., Hibender, S., Hoogenboezem, M., van Broekhoven, A., Girigorie, A. F., Bleeker, N., Hamers, A. A. J., Stap, J., van Buul, J. D., de Vries, C. J. M. & de Waard, V., 2013, In: Arteriosclerosis, thrombosis, and vascular biology. 33, 10, p. 2380-2388Research output: Contribution to journal › Article › Academic › peer-review
29 Citations (Scopus)