Willem van Aalderen

Research output

Research output per year 1984 1990 1991 1992 1993 1994 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2010 2011 2012 2013 2014 2015 2016 2018 2019 2024

• 209 Article
• 26 Comment/Letter to the editor
• 15 Review article
• 4 Chapter
• 5 More
  • 2 Book editing
  • 1 Editorial
  • 1 Erratum/Corrigendum
  • 1 Letter

Research output per year

Research output per year

Search results

• 2024

  Clinical efficacy and satisfaction of a digital wheeze detector in a multicentre randomised controlled trial: the WheezeScan study

  Do, Y. H., van Aalderen, W., Dellbrügger, E., Grenzbach, C., Grigg, J., Grittner, U., Haarman, E., Toro, C. J. H., Karadag, B., Roßberg, S., Weichert, T-M., Whitehouse, A., Pizzulli, A., Matricardi, P. M. & Dramburg, S., 2024, In: ERJ open research. 10, 1, 00518-2023.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2023

  Predictors and associations of the persistent airflow limitation phenotype in asthma: a post-hoc analysis of the ATLANTIS study

  ATLANTIS, CADSET investigators & U-BIOPRED, Jan 2023, In: The Lancet Respiratory Medicine. 11, 1, p. 55-64 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  22 Citations (Scopus)
• 2022

  CO2-VOETAFDRUK VAN INHALATOREN KAN OP VELE FRONTEN OMLAAG

  Translated title of the contribution: Effectiveness and medical indication remain paramount when choosing an inhaler: Carbon footprint of inhalers can be reduced on many frontsDekhuijzen, P. N. R., Snoeck-Stroband, J. B., van Boven, J. F. M. & van Aalderen, W. M., 22 Apr 2022, In: Pharmaceutisch Weekblad. 157, 16, p. 14-17 4 p.

  Research output: Contribution to journal › Article › Professional
• 2021

  Medication Adherence in Patients With Severe Asthma Prescribed Oral Corticosteroids in the U-BIOPRED Cohort

  U-BIOPRED study group, 1 Jul 2021, In: Chest. 160, 1, p. 53-64 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  10 Citations (Scopus)

• The impact of a digital wheeze detector on parental disease management of pre-school children suffering from wheezing—a pilot study

  Dramburg, S., Dellbrügger, E., van Aalderen, W. & Matricardi, P. M., 1 Dec 2021, In: Pilot and feasibility studies. 7, 1, 185.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  8 Citations (Scopus)
• 2020

  Asthma similarities across ProAR (Brazil) and U-BIOPRED (Europe) adult cohorts of contrasting locations, ethnicity and socioeconomic status

  ProAR Study Group & U-BIOPRED Study Groups, 1 Jan 2020, In: Respiratory medicine. 161, 105817.

  Research output: Contribution to journal › Article › Academic › peer-review
  16 Citations (Scopus)

• Connectivity patterns between multiple allergen specific IgE antibodies and their association with severe asthma

  U-BIOPRED Consortium, Oct 2020, In: Journal of allergy and clinical immunology. 146, 4, p. 821-830 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  32 Citations (Scopus)
• 2019

  A minimally invasive tool to study immune response and skin barrier in children with atopic dermatitis

  Hulshof, L., Hack, D. P., Hasnoe, Q. C. J., Dontje, B., Jakasa, I., Riethmüller, C., McLean, W. H. I., van Aalderen, W. M. C., van't Land, B., Kezic, S., Sprikkelman, A. B. & Middelkamp-Hup, M. A., 2019, In: British Journal of Dermatology. 180, 3, p. 621-630

  Research output: Contribution to journal › Article › Academic › peer-review
  54 Citations (Scopus)

• Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation

  Unbiased Biomarkers in Prediction of Respiratory Disease Outcomes study group, 1 Feb 2019, In: Journal of allergy and clinical immunology. 143, 2, p. 577-590 14 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  133 Citations (Scopus)

• IL-17–high asthma with features of a psoriasis immunophenotype

  U-BIOPRED study group, 1 Nov 2019, In: Journal of allergy and clinical immunology. 144, 5, p. 1198-1213 16 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  78 Citations (Scopus)

• Stratification of asthma phenotypes by airway proteomic signatures

  U-BIOPRED study group, Jul 2019, In: Journal of allergy and clinical immunology. 144, 1, p. 70-82

  Research output: Contribution to journal › Article › Academic › peer-review
  57 Citations (Scopus)

• Treatable traits in the European U-BIOPRED adult asthma cohorts

  The U-Biopred Study Group, 2019, In: Allergy. 74, 2, p. 406-411

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  35 Citations (Scopus)

• Voorzetkamers zijn niet één-op-één uitwisselbaar

  Dekhuijzen, P. N. R., van Aalderen, W. M. C., Kievits, R. M. M., Kooistra, J., Hagedoorn, P. & van Boven, J. F. M., 2019, In: Pharmaceutisch Weekblad. 154, 4, p. 10-13

  Research output: Contribution to journal › Article › Professional

• Young children experience little emotional burden during invasive procedures in asthma research

  Padding, A. M., Rutjes, N. W., Hashimoto, S., Vos, A., Staphorst, M. S., van Aalderen, W. M. C. & van der Schee, M. P., 2019, In: European journal of pediatrics. 178, 2, p. 207-211

  Research output: Contribution to journal › Article › Academic › peer-review
  3 Citations (Scopus)
• 2018

  A computational framework for complex disease stratification from multiple large-scale datasets

  the U-BIOPRED Study Group and the eTRIKS Consortium, 2018, In: BMC systems biology. 12, 1, 60.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  28 Citations (Scopus)

• Exploring immune development in infants with moderate to severe atopic dermatitis

  The Clinical Study Group, 2018, In: Frontiers in immunology. 9, MAR, 630.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  17 Citations (Scopus)

• Extrafine Versus Fine Inhaled Corticosteroids in Relation to Asthma Control: A Systematic Review and Meta-Analysis of Observational Real-Life Studies

  Sonnappa, S., McQueen, B., Postma, D. S., Martin, R. J., Roche, N., Grigg, J., Guilbert, T., Gouder, C., Pizzichini, E., Niimi, A., Phipatanakul, W., Chisholm, A., Dandurand, R. J., Kaplan, A., Israel, E., Papi, A., van Aalderen, W. M. C., Usmani, O. S. & Price, D. B., 2018, In: journal of allergy and clinical immunology. In practice. 6, 3, p. 907-915.e7

  Research output: Contribution to journal › Article › Academic › peer-review
  31 Citations (Scopus)

• Lipid phenotyping of lung epithelial lining fluid in healthy human volunteers

  U-BIOPRED study group & The U-Biopred Study Group, 17 Sept 2018, In: Metabolomics. 14, 10, p. 123 123.

  Research output: Contribution to journal › Article › Academic › peer-review
  16 Citations (Scopus)

• Pathway discovery using transcriptomic profiles in adult-onset severe asthma

  U-BIOPRED study group, 2018, In: Journal of allergy and clinical immunology. 141, 4, p. 1280-1290

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  96 Citations (Scopus)

• The Severe Paediatric Asthma Collaborative in Europe (SPACE) ERS Clinical Research Collaboration: enhancing participation of children with asthma in therapeutic trials of new biologics and receptor blockers

  Rusconi, F., Fernandes, R. M., Pijnenburg, M. W. H., Grigg, J., Study group members AMC, van Aalderen, W. & Rutjes, N. W. P., 2018, In: European respiratory journal. 52, 4, 1801665.

  Research output: Contribution to journal › Article › Academic › peer-review
  23 Citations (Scopus)

• The trigger tool as a method to measure harmful medication errors in children

  Maaskant, J. M., Smeulers, M., Bosman, D., Busink, A., van Rijn-Bikker, P., van Aalderen, W. & Vermeulen, H., Jun 2018, In: Journal of Patient Safety. 14, 2, p. 95-100

  Research output: Contribution to journal › Article › Academic › peer-review
  8 Citations (Scopus)

• Zijn voorzetkamers in combinatie met dosisaërosolen in de klinische praktijk uitwisselbaar?

  Dekhuijzen, P. N. R., van Aalderen, W. M. C., Kooistra, J., Hagedoorn, P., van Boven, J. & Kievits, R., 27 Oct 2018, In: Pharmaceutisch Weekblad. 27-10-2018

  Research output: Contribution to journal › Article › Professional
• 2017

  Alterations in the programming of energy metabolism in adolescents with background exposure to dioxins, dl-PCBs and PBDEs

  Leijs, M. M., Koppe, J. G., Vulsma, T., Olie, K., van Aalderen, W. M. C., de Voogt, P., Legler, J. & ten Tusscher, G. W., 12 Sept 2017, In: PLOS ONE. 12, 9, p. e0184006 15 p., e0184006.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  19 Citations (Scopus)

• Asthma-Related Outcomes in Patients Initiating Extrafine Ciclesonide or Fine-Particle Inhaled Corticosteroids

  Postma, D. S., Dekhuijzen, R., van der Molen, T., Martin, R. J., van Aalderen, W., Roche, N., Guilbert, T. W., Israel, E., van Eickels, D., Khalid, J. M., Herings, R. M. C., Overbeek, J. A., Miglio, C., Thomas, V., Hutton, C., Hillyer, E. V. & Price, D. B., Mar 2017, In: Allergy, asthma & immunology research. 9, 2, p. 116-125 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  9 Citations (Scopus)

• BMI predicts exercise induced bronchoconstriction in asthmatic boys

  van Veen, W. J., Driessen, J. M. M., Kersten, E. T. G., van Leeuwen, J. C., Brusse-Keizer, M. G. J., van Aalderen, W. M. C. & Thio, B. J., 2017, In: Pediatric pulmonology. 52, 9, p. 1130-1134

  Research output: Contribution to journal › Article › Academic › peer-review
  9 Citations (Scopus)

• Real-Life Outcomes for Patients with Asthma Prescribed Spacers for Use with Either Extrafine- or Fine-Particle Inhaled Corticosteroids

  Guilbert, T. W., Colice, G., Grigg, J., van Aalderen, W., Martin, R. J., Israel, E., Postma, D. S., Roche, N., Phipatanakul, W., Hillyer, E. V., Evans, J. M., Dolovich, M. B. & Price, D. B., 2017, In: journal of allergy and clinical immunology. In practice. 5, 4, p. 1040-1049.e4

  Research output: Contribution to journal › Article › Academic › peer-review
  14 Citations (Scopus)

• Risk of pneumonia in obstructive lung disease: A real-life study comparing extra-fine and fine-particle inhaled corticosteroids

  Sonnappa, S., Martin, R., Israel, E., Postma, D., van Aalderen, W., Burden, A., Usmani, O. S. & Price, D. B., 2017, In: PLOS ONE. 12, 6, p. e0178112

  Research output: Contribution to journal › Article › Academic › peer-review
  23 Citations (Scopus)
• 2016

  Add-on LABA in a separate inhaler as asthma step-up therapy versus increased dose of ICS or ICS/LABA combination inhaler

  Price, D. B., Colice, G., Israel, E., Roche, N., Postma, D. S., Guilbert, T. W., van Aalderen, W. M. C., Grigg, J., Hillyer, E. V., Thomas, V. & Martin, R. J., 2016, In: ERJ open research. 2, 2, p. 00106-2015

  Research output: Contribution to journal › Article › Academic › peer-review
  9 Citations (Scopus)

• Biomarkers in Exhaled Breath Condensate Are Not Predictive for Pulmonary Exacerbations in Children with Cystic Fibrosis: Results of a One-Year Observational Study

  van Horck, M., Alonso, A., Wesseling, G., de Winter-de Groot, K., van Aalderen, W., Hendriks, H., Winkens, B., Rijkers, G., Jöbsis, Q. & Dompeling, E., 2016, In: PLOS ONE. 11, 4, p. e0152156

  Research output: Contribution to journal › Article › Academic › peer-review
  7 Citations (Scopus)

• CT-abnormalities, bacteriology and symptoms of sinonasal disease in children with Cystic Fibrosis

  Berkhout, M. C., Klerx-Melis, F., Fokkens, W. J., Nuijsink, M., van Aalderen, W. M. C. & Heijerman, H. G. M., 2016, In: Journal of cystic fibrosis. 15, 6, p. 816-824

  Research output: Contribution to journal › Article › Academic › peer-review
  20 Citations (Scopus)

• Effectiveness of initiating extrafine-particle versus fine-particle inhaled corticosteroids as asthma therapy in the Netherlands

  van der Molen, T., Postma, D. S., Martin, R. J., Herings, R. M. C., Overbeek, J. A., Thomas, V., Miglio, C., Dekhuijzen, R., Roche, N., Guilbert, T., Israel, E., van Aalderen, W., Hillyer, E. V., van Rysewyk, S. & Price, D. B., 2016, In: BMC Pulmonary Medicine. 16, 1, p. 80

  Research output: Contribution to journal › Article › Academic › peer-review
  16 Citations (Scopus)

• Prevalence of rhinoviruses in young children of an unselected birth cohort from the Netherlands

  Wildenbeest, J. G., van der Schee, M. P., Hashimoto, S., Benschop, K. S. M., Minnaar, R. P., Sprikkelman, A. B., Haarman, E. G., van Aalderen, W. M. C., Sterk, P. J., Pajkrt, D. & Wolthers, K. C., Aug 2016, In: Clinical Microbiology and Infection. 22, 8, p. 736.e9-736.e15

  Research output: Contribution to journal › Article › Academic › peer-review
  21 Citations (Scopus)

• Stability and predictiveness of multiple trigger and episodic viral wheeze in preschoolers

  van Wonderen, K. E., Geskus, R. B., van Aalderen, W. M. C., Mohrs, J., Bindels, P. J. E., van der Mark, L. B. & ter Riet, G., 2016, In: Clinical and experimental allergy. 46, 6, p. 837-847

  Research output: Contribution to journal › Article › Academic › peer-review
  27 Citations (Scopus)
• 2015

  Altered exhaled biomarker profiles in children during and after rhinovirus-induced wheeze

  van der Schee, M. P., Hashimoto, S., Schuurman, A. C., van Driel, J. S. R., Adriaens, N., van Amelsfoort, R. M., Snoeren, T., Regenboog, M., Sprikkelman, A. B., Haarman, E. G., van Aalderen, W. M. C. & Sterk, P. J., 2015, In: European respiratory journal. 45, 2, p. 440-448

  Research output: Contribution to journal › Article › Academic › peer-review
  43 Citations (Scopus)

• Breathomics in lung disease

  van der Schee, M. P., Paff, T., Brinkman, P., van Aalderen, W. M. C., Haarman, E. G. & Sterk, P. J., 2015, In: Chest. 147, 1, p. 224-231

  Research output: Contribution to journal › Article › Academic › peer-review
  143 Citations (Scopus)

• Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort

  AUTHOR GROUP, 2015, In: European respiratory journal. 46, 5, p. 1308-1321

  Research output: Contribution to journal › Article › Academic › peer-review
  420 Citations (Scopus)

• Increased Dose of Inhaled Corticosteroid versus Add-On Long-acting β-Agonist for Step-Up Therapy in Asthma

  Israel, E., Roche, N., Martin, R. J., Colice, G., Dorinsky, P. M., Postma, D. S., Guilbert, T. W., van Aalderen, W. M. C., Grigg, J., Hillyer, E. V., Burden, A., von Ziegenweidt, J., Thomas, V. & Price, D. B., 2015, In: Annals of the American Thoracic Society. 12, 6, p. 798-806

  Research output: Contribution to journal › Article › Academic › peer-review
  18 Citations (Scopus)

• Remaining symptoms in half the children treated for milk allergy

  Petrus, N. C. M., Schoemaker, A-F. A., van Hoek, M. W., Jansen, L., Jansen-van der Weide, M. C., van Aalderen, W. M. C. & Sprikkelman, A. B., 2015, In: European journal of pediatrics. 174, 6, p. 759-765

  Research output: Contribution to journal › Article › Academic › peer-review
  24 Citations (Scopus)

• Small-particle Inhaled Corticosteroid as First-line or Step-up Controller Therapy in Childhood Asthma

  van Aalderen, W. M. C., Grigg, J., Guilbert, T. W., Roche, N., Israel, E., Martin, R. J., Colice, G., Postma, D. S., Hillyer, E. V., Burden, A., Thomas, V., von Ziegenweidt, J. & Price, D., 2015, In: journal of allergy and clinical immunology. In practice. 3, 5, p. 721-31.e16

  Research output: Contribution to journal › Article › Academic › peer-review
  36 Citations (Scopus)

• The burden of severe asthma in childhood and adolescence: results from the paediatric U-BIOPRED cohorts

  AUTHOR GROUP, 2015, In: European respiratory journal. 46, 5, p. 1322-1333

  Research output: Contribution to journal › Article › Academic › peer-review
  175 Citations (Scopus)
• 2014

  Abusive head trauma: differentiation between impact and non-impact cases based on neuroimaging findings and skeletal surveys

  Sieswerda-Hoogendoorn, T., Robben, S. G. F., Karst, W. A., Moesker, F. M., van Aalderen, W. M., Laméris, J. S. & van Rijn, R. R., 2014, In: European Journal of Radiology. 83, 3, p. 584-588

  Research output: Contribution to journal › Article › Academic › peer-review
  11 Citations (Scopus)

• Comparing the effectiveness of small-particle versus large-particle inhaled corticosteroid in COPD

  Postma, D. S., Roche, N., Colice, G., Israel, E., Martin, R. J., van Aalderen, W. M., Grigg, J., Burden, A., Hillyer, E. V., von Ziegenweidt, J., Gopalan, G. & Price, D., 2014, In: International journal of chronic obstructive pulmonary disease. 9, p. 1163-1186

  Research output: Contribution to journal › Article › Academic › peer-review
  25 Citations (Scopus)

• Cost-effectiveness of initiating extrafine- or standard size-particle inhaled corticosteroid for asthma in two health-care systems: a retrospective matched cohort study

  Martin, R. J., Price, D., Roche, N., Israel, E., van Aalderen, W. M. C., Grigg, J., Postma, D. S., Guilbert, T. W., Hillyer, E. V., Burden, A., von Ziegenweidt, J. & Colice, G., 2014, In: Npj Primary Care Respiratory Medicine. 24, p. 14081

  Research output: Contribution to journal › Article › Academic › peer-review
  17 Citations (Scopus)

• Exclusively breastfed infants at risk for false negative double blind placebo controlled milk challenge

  Petrus, N. C. M., Kole, E. A., Schoemaker, A. A., van Aalderen, W. M. C. & Sprikkelman, A. B., 2014, In: European annals of allergy and clinical immunology. 46, 1, p. 43-45

  Research output: Contribution to journal › Article › Academic › peer-review

• Inpatient treatment of children and adolescents with severe obesity in the Netherlands: a randomized clinical trial

  van der Baan-Slootweg, O., Benninga, M. A., Beelen, A., van der Palen, J., Tamminga-Smeulders, C., Tijssen, J. G. P. & van Aalderen, W. M. C., 2014, In: JAMA pediatrics. 168, 9, p. 807-814

  Research output: Contribution to journal › Article › Academic › peer-review
  74 Citations (Scopus)

• Opportunities to diagnose chronic obstructive pulmonary disease in routine care in the UK: a retrospective study of a clinical cohort

  AUTHOR GROUP, 2014, In: lancet. Respiratory medicine. 2, 4, p. 267-276

  Research output: Contribution to journal › Article › Academic › peer-review
  143 Citations (Scopus)

• Predicting asthma in preschool children at high risk presenting in primary care: development of a clinical asthma prediction score

  van der Mark, L. B., van Wonderen, K. E., Mohrs, J., van Aalderen, W. M. C., ter Riet, G. & Bindels, P. J. E., 2014, In: Primary care respiratory journal. 23, 1, p. 52-59

  Research output: Contribution to journal › Article › Academic › peer-review
  36 Citations (Scopus)

• Preventable Errors with Nonopioid Analgesics and Antiemetic Drugs May Increase Burden in Surgical Pediatric Patients

  Maaskant, J., Bosman, D., van Rijn-Bikker, P., van Aalderen, W. & Vermeulen, H., 2014, In: European journal of pediatric surgery. 24, 5, p. 381-388 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  9 Citations (Scopus)

• Problematic severe asthma in children treated at high altitude: Tapering the dose while improving control

  Van De Griendt, E. J., Verkleij, M., Menno Douwes, J., Van Aalderen, W. M. C. & Geenen, R., 1 Jan 2014, In: Journal of Asthma. 51, 3, p. 315-319 5 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  7 Citations (Scopus)

• The influence of perinatal and current dioxine and PCB exposure on reproductive parameters (sex ratio, menstrual cycle characteristics, endometriosis, semen quality and prematurity): A review

  Leijs, M. M., van der Linden, L. M., Koppe, J. G., Olie, K., van Aalderen, W. M. C. & Ten Tusscher, G. W., 2014, In: Biomonitoring. 1, 11, p. 10.2478/bimo-2014-0001--

  Research output: Contribution to journal › Article › Academic › peer-review