Projects per year
Personal profile
specialisation
Liver directed gene therapy for inherited liver disorders
Research interests
gene therapy
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Bosma P.J.: Novel therapies for liver disease
Bosma, P., ten Bloemendaal, L., Aronson, S., Bolier, A., van Dijk, R., Langedijk, J., Naik, J., Shi, X. & Berlingieri, S.
1/02/2007 → …
Project: Research
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Oude Elferink R.P.J.: Hepatic transport processes and Bioartificial Liver Support
Abdelrahman Abubakr Adam, A., Appelman, M., Bolier, A., Chang, J., Chen, H., van Dijk, R., Donkers, J., Folmer, D., Hohenester, S., Langedijk, J., van der Mark, V., Naik, J., van Niekerk, J., Roscam Abbing, R., Shi, X., Slijepcevic, D., van de Wiel, S., Oude Elferink, R., van de Graaf, S., Paulusma, C., de Waart, R., Hoekstra, R., Chamuleau, R., Duijst, S., Ho - Mok, K. S., Terlouw - Tolenaars, D. & de Jonge, H.
1/01/2006 → 1/03/2023
Project: Research
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Efficacy of AAV8-hUGT1A1 with Rapamycin in neonatal, suckling, and juvenile rats to model treatment in pediatric CNs patients
Shi, X., Aronson, S. J., ten Bloemendaal, L., Duijst, S., Bakker, R. S., de Waart, D. R., Bortolussi, G., Collaud, F., Oude Elferink, R. P., Muro, A. F., Mingozzi, F., Ronzitti, G. & Bosma, P. J., 12 Mar 2021, In: Molecular therapy. Methods & clinical development. 20, p. 287-297 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access6 Citations (Scopus) -
Long-term effects of biliverdin reductase a deficiency in ugt1−/− mice: impact on redox status and metabolism
Bortolussi, G., Shi, X., Bloemendaal, L. T., Banerjee, B., de Waart, D. R., Baj, G., Chen, W., Oude Elferink, R. P., Beuers, U., Paulusma, C. C., Stocker, R., Muro, A. F. & Bosma, P. J., 1 Dec 2021, In: Antioxidants. 10, 12, 2029.Research output: Contribution to journal › Article › Academic › peer-review
Open Access3 Citations (Scopus) -
Low efficacy of recombinant SV40 in Ugt1a1-/- mice with severe inherited hyperbilirubinemia
Shi, X., Bortolussi, G., ten Bloemendaal, L., Duijst, S., Muro, A. F. & Bosma, P. J., 1 Apr 2021, In: PLOS ONE. 16, 4 April, e0250605.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
New avenues in gene therapy for inherited liver disease
Shi, X., 2021, 182 p.Research output: PhD Thesis › Phd-Thesis - Research and graduation internal
Open Access -
A Quantitative In Vitro Potency Assay for Adeno-Associated Virus Vectors Encoding for the UGT1A1 Transgene
Aronson, S. J., Bakker, R. S., Moenis, S., van Dijk, R., Bortolussi, G., Collaud, F., Shi, X., Duijst, S., ten Bloemendaal, L., Ronzitti, G., Muro, A. F., Mingozzi, F., Beuers, U. & Bosma, P. J., 11 Sept 2020, In: Molecular therapy. Methods & clinical development. 18, p. 250-258 9 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access6 Citations (Scopus)