Blankevoort L.: Diagnosis and treatment of joint disorders

  • Blankevoort, Leendert (Principal investigator)
  • van Dijk, Cornelis (Staff)
  • Kerkhoffs, Gino (Staff)
  • Schafroth, Matthias (Staff)
  • Strackee, Simon (Staff)
  • van den Bekerom, Michel (Internal PhD candidate)
  • Campo, Martinus (Internal PhD candidate)
  • Dvinskikh, Natalya (Internal PhD candidate)
  • Gerards, Rogier (Internal PhD candidate)
  • Kievit, Arthur (Internal PhD candidate)
  • de Leeuw, Peter (Internal PhD candidate)
  • Muller, Bart (Internal PhD candidate)
  • Pahlplatz, Thijs (Internal PhD candidate)
  • Raven, Eric (Internal PhD candidate)
  • Witjes, Suzanne (Internal PhD candidate)
  • Zengerink, Maartje (Internal PhD candidate)
  • Raven, Eric E. J. (External PhD candidate)

Project Details


Research line
Research in the department of Orthopaedic Surgery is organized in Orthopaedic Research Center Amsterdam (ORCA). Diagnosis and treatment of joint disorders
The research line is aimed at the development and evaluation of diagnostic methods and therapeutic methods for joints disorders with a focus on minimally invasive and arthroscopic procedures. It encompasses fundamental biologic , functional anatomic and biomechanical research just like clinical trials and development of clinical guidelines. The focus is in accordance with the clinical cores of the department, i.e. the joints of the lower extremity, in particular the ankle and knee and orthopaedic sports medicine. For the ankle the topics are diagnosis, treatment and follow-up of osteochondral defects and of impingement syndromes. For the knee the topics are total knee replacement and repair of the anterior cruciate ligament.
Past projects evaluated the mechanism of biologic repair of osteochondral defects in an animal model, a theory for the development subchondral talar cysts in the ankle and the biomechanics of correction osteotomies of the hindfoot. Several aspects of anterior knee pain after total knee replacement were addressed, in a prospective clinical trial comparing a fixed-bearing and mobile bearing total knee replacement and the possible effect of malplacement. Primary repair of the torn ACL is proven to be feasible in an animal model. Proof of the healing potential was found in bioosies of the human ACL.
The current projects are biomechanical and geometrical modeling of the hindfoot for evaluation of joint function in relation to pathologies, improving imaging techniques for detecting bony impingement in the ankle, anatomical features as prognostic factors for developing chronically instable ankles, development of primary repair techniques for the torn anterior cruciate ligament, development of a technique for diagnosing a loose total knee replacement.
Effective start/end date1/10/2006 → …