TY - JOUR
T1 - Seroprevalence of Toxoplasma gondii and associated risk factors for infection in the Netherlands
T2 - third cross-sectional national study
AU - van den Berg, Oda E.
AU - Stanoeva, Kamelia R.
AU - Zonneveld, Rens
AU - Hoek-van Deursen, Denise
AU - van der Klis, Fiona
AU - van de Kassteele, Jan
AU - Franz, Eelco
AU - Opsteegh, Marieke
AU - Friesema, Ingrid H. M.
AU - Kortbeek, Laetitia M.
N1 - Publisher Copyright: © The Author(s), 2023. Published by Cambridge University Press.
PY - 2023/7/28
Y1 - 2023/7/28
N2 - A third nationally representative serosurvey was performed to study the changes in Toxoplasma gondii (T. gondii) seroprevalence in the Netherlands over a 20-year time span and to identify and confirm risk factors for acquired toxoplasmosis. This cross-sectional study (conducted in 2016/2017) was designed similarly to the previous two studies (1995/1996 and 2006/2007) and included a questionnaire and serum sampling among Dutch residents. Factors associated with seropositivity for T. gondii were determined using multivariable analysis of the questionnaire-derived data. The earlier observed decrease in T. gondii seroprevalence between 1995/1996 and 2006/2007 (from 40.5% to 26.0%) did not continue into 2016/2017 (29.9%). Similarly to the previous studies, the seroprevalence increased with age and varied among regions. In all studies, higher T. gondii seropositivity was associated with increasing age, lower educational level, not living in the Southeast, and eating raw or semi-cooked pork. The incidence of congenital toxoplasmosis was estimated at 1.3/1000 (95% CI 0.9-1.8) live-born children in 2017. As the seroprevalence of T. gondii in the Netherlands did not decrease over the last decade, an increase in public health awareness is needed and prevention measures may need to be taken to achieve a further reduction in T. gondii infections in the Netherlands.
AB - A third nationally representative serosurvey was performed to study the changes in Toxoplasma gondii (T. gondii) seroprevalence in the Netherlands over a 20-year time span and to identify and confirm risk factors for acquired toxoplasmosis. This cross-sectional study (conducted in 2016/2017) was designed similarly to the previous two studies (1995/1996 and 2006/2007) and included a questionnaire and serum sampling among Dutch residents. Factors associated with seropositivity for T. gondii were determined using multivariable analysis of the questionnaire-derived data. The earlier observed decrease in T. gondii seroprevalence between 1995/1996 and 2006/2007 (from 40.5% to 26.0%) did not continue into 2016/2017 (29.9%). Similarly to the previous studies, the seroprevalence increased with age and varied among regions. In all studies, higher T. gondii seropositivity was associated with increasing age, lower educational level, not living in the Southeast, and eating raw or semi-cooked pork. The incidence of congenital toxoplasmosis was estimated at 1.3/1000 (95% CI 0.9-1.8) live-born children in 2017. As the seroprevalence of T. gondii in the Netherlands did not decrease over the last decade, an increase in public health awareness is needed and prevention measures may need to be taken to achieve a further reduction in T. gondii infections in the Netherlands.
KW - The Netherlands
KW - Toxoplasma gondii
KW - risk factors
KW - serology
KW - seroprevalence
UR - http://www.scopus.com/inward/record.url?scp=85167657337&partnerID=8YFLogxK
U2 - https://doi.org/10.1017/S095026882300122X
DO - https://doi.org/10.1017/S095026882300122X
M3 - Article
C2 - 37503608
SN - 0950-2688
VL - 151
JO - Epidemiology and Infection
JF - Epidemiology and Infection
M1 - e136
ER -