TY - JOUR
T1 - Heat treatment for giant cell tumors of bone
T2 - A systematic review
AU - Schoutens, Carlijn
AU - Verspoor, Floortje G. M.
N1 - Publisher Copyright: © The Author(s) 2023.
PY - 2023/9/1
Y1 - 2023/9/1
N2 - This systematic review evaluates the effects of heat treatments in de novo, residual and recurrent giant cell tumors of bone (GCTB). Studies were eligible for inclusion if one of the following treatments was administered: radiofrequency ablation (RFA), microwave ablation, argon cauterization, electrocauterization and hot liquid treatment. The primary outcome was recurrence. Secondary outcomes were complications, pain, function, and quality of life. Recurrence rates for microwave ablation as an adjuvant to intralesional curettage were 0%, 4% and 10% (3 retrospective single-group studies); for argon cauterization 4%, 8% and 26% (3 cohort studies); electrocauterization 0% to 33% (8 cohort studies); and hot liquid 9.5% and 24% (2 cohort studies). Follow-up was generally ≥24 months. Data on pain, function and quality of life were scarce. Complications included infection and secondary osteoarthritis. Current evidence does not demonstrate or exclude an effect of heat treatments on recurrence in GCTB. Further research should objectify if (subgroups of) patients benefit from these treatments.
AB - This systematic review evaluates the effects of heat treatments in de novo, residual and recurrent giant cell tumors of bone (GCTB). Studies were eligible for inclusion if one of the following treatments was administered: radiofrequency ablation (RFA), microwave ablation, argon cauterization, electrocauterization and hot liquid treatment. The primary outcome was recurrence. Secondary outcomes were complications, pain, function, and quality of life. Recurrence rates for microwave ablation as an adjuvant to intralesional curettage were 0%, 4% and 10% (3 retrospective single-group studies); for argon cauterization 4%, 8% and 26% (3 cohort studies); electrocauterization 0% to 33% (8 cohort studies); and hot liquid 9.5% and 24% (2 cohort studies). Follow-up was generally ≥24 months. Data on pain, function and quality of life were scarce. Complications included infection and secondary osteoarthritis. Current evidence does not demonstrate or exclude an effect of heat treatments on recurrence in GCTB. Further research should objectify if (subgroups of) patients benefit from these treatments.
KW - ablation techniques
KW - bone tissue
KW - cautery
KW - giant cell tumors of bone
KW - neoplasms
KW - recurrence
KW - thermal treatments
UR - http://www.scopus.com/inward/record.url?scp=85171665739&partnerID=8YFLogxK
U2 - https://doi.org/10.1177/10225536231202157
DO - https://doi.org/10.1177/10225536231202157
M3 - Article
C2 - 37726111
SN - 1022-5536
VL - 31
JO - Journal of Orthopaedic Surgery
JF - Journal of Orthopaedic Surgery
IS - 3
ER -