TY - JOUR
T1 - Influence of prenatal exposure to mercury, perceived stress, and depression on birth outcomes in suriname: Results from the mekitamara study
AU - Gokoel, Anisma R.
AU - Zijlmans, Wilco C. W. R.
AU - Covert, Hannah H.
AU - Wahid, Firoz Abdoel
AU - Shankar, Arti
AU - Macdonald-Ottevanger, M. Sigrid
AU - Hindori-Mohangoo, Ashna D.
AU - Wickliffe, Jeffrey K.
AU - Lichtveld, Maureen Y.
AU - Harville, Emily W.
N1 - Funding Information: Funding: Research reported in this publication was supported by the Fogarty International Center of the National Institutes of Health under Award Numbers: U01TW010087 and U2RTW010104. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. Publisher Copyright: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/6/1
Y1 - 2020/6/1
N2 - Prenatal exposure to mercury, stress, and depression may have adverse effects on birth outcomes. Little is known on the influence of chemical and non-chemical stressors on birth outcomes in the country of Suriname. We assessed the influence of prenatal exposure to mercury, perceived stress, and depression on adverse birth outcomes in 1143 pregnant Surinamese women who participated in the Caribbean Consortium for Research in Environmental and Occupational Health-MeKiTamara prospective cohort study. Associations between mercury (≥1.1 µg/g hair, USEPA action level/top versus bottom quartile), probable depression (Edinburgh Depression Scale ≥12), high perceived stress (Cohen’s Perceived Stress Scale ≥20), and adverse birth outcomes (low birthweight (<2500 g), preterm birth (<37 completed weeks of gestation), and low Apgar score (<7 at 5 min)) were assessed using bivariate and multivariate logistic regressions. Prevalence of elevated mercury levels, high perceived stress, and probable depression were 37.5%, 27.2%, and 22.4%, respectively. Mercury exposure was significantly associated with preterm birth in the overall study cohort (OR 2.47; 95% CI 1.05–5.83) and perceived stress with a low Apgar score (OR 9.73; 95% CI 2.03–46.70). Depression was not associated with any birth outcomes. These findings can inform policy-and practice-oriented solutions to improve maternal and child health in Suriname.
AB - Prenatal exposure to mercury, stress, and depression may have adverse effects on birth outcomes. Little is known on the influence of chemical and non-chemical stressors on birth outcomes in the country of Suriname. We assessed the influence of prenatal exposure to mercury, perceived stress, and depression on adverse birth outcomes in 1143 pregnant Surinamese women who participated in the Caribbean Consortium for Research in Environmental and Occupational Health-MeKiTamara prospective cohort study. Associations between mercury (≥1.1 µg/g hair, USEPA action level/top versus bottom quartile), probable depression (Edinburgh Depression Scale ≥12), high perceived stress (Cohen’s Perceived Stress Scale ≥20), and adverse birth outcomes (low birthweight (<2500 g), preterm birth (<37 completed weeks of gestation), and low Apgar score (<7 at 5 min)) were assessed using bivariate and multivariate logistic regressions. Prevalence of elevated mercury levels, high perceived stress, and probable depression were 37.5%, 27.2%, and 22.4%, respectively. Mercury exposure was significantly associated with preterm birth in the overall study cohort (OR 2.47; 95% CI 1.05–5.83) and perceived stress with a low Apgar score (OR 9.73; 95% CI 2.03–46.70). Depression was not associated with any birth outcomes. These findings can inform policy-and practice-oriented solutions to improve maternal and child health in Suriname.
KW - Adverse birth outcomes
KW - Apgar score
KW - Birthweight
KW - Maternal depression
KW - Mercury exposure
KW - Perceived stress
KW - Preterm birth
KW - Suriname
UR - http://www.scopus.com/inward/record.url?scp=85086798908&partnerID=8YFLogxK
U2 - https://doi.org/10.3390/ijerph17124444
DO - https://doi.org/10.3390/ijerph17124444
M3 - Article
C2 - 32575788
SN - 1661-7827
VL - 17
SP - 1
EP - 14
JO - International journal of environmental research and public health
JF - International journal of environmental research and public health
IS - 12
M1 - 4444
ER -