TY - JOUR
T1 - Predicted Need for Atrial and Ventricular Pacing Per Indication Group in Patients With Dual-Chamber Pacemakers
AU - Breeman, Karel T. N.
AU - Dijkshoorn, Leonard A.
AU - Wilde, Arthur A. M.
AU - Tjong, Fleur V. Y.
AU - Knops, Reinoud E.
N1 - Publisher Copyright: © 2023 The Authors
PY - 2023/5
Y1 - 2023/5
N2 - Background: Bradyarrhythmias are adequately treated with pacemakers. There are different pacing modes (single-chamber, dual-chamber, cardiac resynchronisation therapy [CRT] and conduction system pacing [CSP]) and a choice between leadless or transvenous pacemakers. The expected pacing need is important for determining optimal pacing mode and device type. This study aimed to evaluate atrial pacing (AP) and ventricular pacing (VP) percentages over time for the most common pacing indications. Methods: Included patients were aged ≥18 years with a dual-chamber rate-modulated [DDD(R)] pacemaker implantation and ≥1 year of follow-up at a tertiary centre between January 2008 and January 2020. Baseline characteristics, AP and VP at yearly follow-up visits up to 6 years after implantation were retrieved from the medical records. Results: A total of 381 patients were included. Primary pacing indications were incomplete atrioventricular block (AVB) in 85 (22%), complete AVB in 156 (41%) and sinus node dysfunction (SND) in 140 (37%) patients. Mean age at implantation was 71±14, 69±17 and 68±14 years, respectively (p=0.23). Median follow-up was 42 months (25–68 months). Overall, AP was highest in SND with median 37% (7%–75%) versus 7% (1%–26%) in incomplete AVB and 3% (1%–16%) in complete AVB (p<0.001); VP was highest in complete AVB with median 98% (43%–100%) versus 44% (7%–94%) in incomplete AVB and 3% (1%–14%) in SND (p<0.001). Ventricular pacing significantly increased over time in patients with incomplete AVB and SND (both p=0.001). Conclusions: These results confirm the pathophysiology of different pacing indications, causing clear differences in pacing need and expected battery longevity. They may help guide optimal pacing mode and suitability for leadless or physiological pacing.
AB - Background: Bradyarrhythmias are adequately treated with pacemakers. There are different pacing modes (single-chamber, dual-chamber, cardiac resynchronisation therapy [CRT] and conduction system pacing [CSP]) and a choice between leadless or transvenous pacemakers. The expected pacing need is important for determining optimal pacing mode and device type. This study aimed to evaluate atrial pacing (AP) and ventricular pacing (VP) percentages over time for the most common pacing indications. Methods: Included patients were aged ≥18 years with a dual-chamber rate-modulated [DDD(R)] pacemaker implantation and ≥1 year of follow-up at a tertiary centre between January 2008 and January 2020. Baseline characteristics, AP and VP at yearly follow-up visits up to 6 years after implantation were retrieved from the medical records. Results: A total of 381 patients were included. Primary pacing indications were incomplete atrioventricular block (AVB) in 85 (22%), complete AVB in 156 (41%) and sinus node dysfunction (SND) in 140 (37%) patients. Mean age at implantation was 71±14, 69±17 and 68±14 years, respectively (p=0.23). Median follow-up was 42 months (25–68 months). Overall, AP was highest in SND with median 37% (7%–75%) versus 7% (1%–26%) in incomplete AVB and 3% (1%–16%) in complete AVB (p<0.001); VP was highest in complete AVB with median 98% (43%–100%) versus 44% (7%–94%) in incomplete AVB and 3% (1%–14%) in SND (p<0.001). Ventricular pacing significantly increased over time in patients with incomplete AVB and SND (both p=0.001). Conclusions: These results confirm the pathophysiology of different pacing indications, causing clear differences in pacing need and expected battery longevity. They may help guide optimal pacing mode and suitability for leadless or physiological pacing.
KW - Atrioventricular block
KW - Dual-chamber pacemaker
KW - Pacing percentage
KW - Sinus node dysfunction
UR - http://www.scopus.com/inward/record.url?scp=85151443544&partnerID=8YFLogxK
U2 - https://doi.org/10.1016/j.hlc.2023.02.007
DO - https://doi.org/10.1016/j.hlc.2023.02.007
M3 - Article
C2 - 36990960
SN - 1443-9506
VL - 32
SP - 629
EP - 637
JO - Heart, lung & circulation
JF - Heart, lung & circulation
IS - 5
ER -