TY - JOUR
T1 - Standardized reporting of pulmonary transfusion complications
T2 - Development of a model reporting form and flowchart
AU - van Wonderen, Stefan F.
AU - Peters, Anna L.
AU - Grey, Sharran
AU - Rajbhandary, Srijana
AU - de Jonge, Layla L.
AU - Andrzejewski, Chester
AU - Narayan, Shruthi
AU - Wiersum-Osselton, Johanna C.
AU - Vlaar, Alexander P. J.
N1 - Funding Information: The authors acknowledge and would like to thank dr. T. Latham from the Bristol Institute for Transfusion Sciences, National Health Service Blood and Transplant for participating in the steering group and commenting on the manuscript. Publisher Copyright: © 2023 The Authors. Transfusion published by Wiley Periodicals LLC on behalf of AABB.
PY - 2023/6
Y1 - 2023/6
N2 - Background: Pulmonary complications of blood transfusion, including transfusion-related acute lung injury (TRALI), transfusion-associated circulatory overload (TACO), and transfusion-associated dyspnea, are generally underdiagnosed and under-reported. The international TRALI and TACO definitions have recently been updated. Currently, no standardized pulmonary transfusion reaction reporting form exists and most of the hemovigilance forms have not yet incorporated the updated definitions. We developed a harmonized reporting form, aimed at improved data collection on pulmonary transfusion reactions for hemovigilance and research purposes by developing a standardized model reporting form and flowchart. Materials and Methods: Using a modified Delphi method among an international, multidisciplinary panel of 24 hemovigilance experts, detailed recommendations were developed for a standardized model reporting form for pulmonary complications of blood transfusion. Two Delphi rounds, including scoring systems, took place and several subsequent meetings were held to discuss issues and obtain consensus. Additionally, a flowchart was developed incorporating recently published redefinitions of pulmonary transfusion reactions. Results: In total, 17 participants completed the first questionnaire (70.8% response rate) and 14 participants completed the second questionnaire (58.3% response rate). According to the results from the questionnaires, the standardized model reporting form was divided into various subcategories: general information, patient history and transfusion characteristics, reaction details, investigations, treatment and supportive care, narrative, and transfused product. Conclusion: In this article, we present the recommendations from a global group of experts in the hemovigilance field. The standardized model reporting form and flowchart provide an initiative that may improve data collected to address pulmonary transfusion reactions.
AB - Background: Pulmonary complications of blood transfusion, including transfusion-related acute lung injury (TRALI), transfusion-associated circulatory overload (TACO), and transfusion-associated dyspnea, are generally underdiagnosed and under-reported. The international TRALI and TACO definitions have recently been updated. Currently, no standardized pulmonary transfusion reaction reporting form exists and most of the hemovigilance forms have not yet incorporated the updated definitions. We developed a harmonized reporting form, aimed at improved data collection on pulmonary transfusion reactions for hemovigilance and research purposes by developing a standardized model reporting form and flowchart. Materials and Methods: Using a modified Delphi method among an international, multidisciplinary panel of 24 hemovigilance experts, detailed recommendations were developed for a standardized model reporting form for pulmonary complications of blood transfusion. Two Delphi rounds, including scoring systems, took place and several subsequent meetings were held to discuss issues and obtain consensus. Additionally, a flowchart was developed incorporating recently published redefinitions of pulmonary transfusion reactions. Results: In total, 17 participants completed the first questionnaire (70.8% response rate) and 14 participants completed the second questionnaire (58.3% response rate). According to the results from the questionnaires, the standardized model reporting form was divided into various subcategories: general information, patient history and transfusion characteristics, reaction details, investigations, treatment and supportive care, narrative, and transfused product. Conclusion: In this article, we present the recommendations from a global group of experts in the hemovigilance field. The standardized model reporting form and flowchart provide an initiative that may improve data collected to address pulmonary transfusion reactions.
KW - anaphylaxis
KW - flowchart
KW - hemovigilance
KW - reporting
KW - transfusion-associated circulatory overload
KW - transfusion-associated dyspnea
KW - transfusion-related acute lung injury
UR - http://www.scopus.com/inward/record.url?scp=85153228269&partnerID=8YFLogxK
U2 - https://doi.org/10.1111/trf.17346
DO - https://doi.org/10.1111/trf.17346
M3 - Article
C2 - 37060282
SN - 0041-1132
VL - 63
SP - 1161
EP - 1171
JO - Transfusion
JF - Transfusion
IS - 6
ER -