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• 2022

  Anti–PD-1 Efficacy in Patients with Metastatic Urothelial Cancer Associates with Intratumoral Juxtaposition of T Helper-Type 1 and CD8 ^þ T cells

  Rijnders, M., Balcioglu, H. E., Robbrecht, D. G. J., Oostvogels, A. A. M., Wijers, R., Aarts, M. J. B., Hamberg, P., van Leenders, G. J. L. H., Nakauma-González, J. A., Voortman, J., Westgeest, H. M., Boormans, J. L., de Wit, R., Lolkema, M., van der Veldt, A. A. M. & Debets, R., 1 Jan 2022, In: Clinical cancer research : an official journal of the American Association for Cancer Research. 28, 1, p. 215-226 12 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• Antithrombotic Therapy in Patients With Atrial Fibrillation After Acute Coronary Syndromes or Percutaneous Intervention

  Harskamp, R. E., Fanaroff, A. C., Lopes, R. D., Wojdyla, D. M., Goodman, S. G., Thomas, L. E., Aronson, R., Windecker, S., Mehran, R., Granger, C. B. & Alexander, J. H., 8 Feb 2022, In: Journal of the American College of Cardiology. 79, 5, p. 417-427 11 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

• Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but without dementia

  Kwan, J., Hafdi, M., Chiang, L. L. W., Myint, P. K., Wong, L. S. & Quinn, T. J., 13 Jul 2022, In: Cochrane Database of Systematic Reviews. 2022, 7, CD012269.

  Research output: Contribution to Journal › Review article › Academic › peer-review

• An unexplored angle: T cell antigen discoveries reveal a marginal contribution of proteasome splicing to the immunogenic MHC class I antigen pool

  Verkerk, T., Koomen, S. J. I., Fuchs, K. J., Griffioen, M. & Spaapen, R. M., 19 Jul 2022, In: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 119, 29, e2119736119.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• An update on hospital admissions for acute pancreatitis in the Netherlands (2013-2019)

  Spanier, B. W. M., Bruno, M. & Dijkgraaf, M., 1 Jun 2022, In: European journal of gastroenterology & hepatology. 34, 6, p. 726-727 2 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

• Anxiety, depression, and PTSD symptoms among high school students in china in response to the COVID-19 pandemic and lockdown

  Cao, C., Wang, L., Fang, R., Liu, P., Bi, Y., Luo, S., Grace, E. & Olff, M., 1 Jan 2022, In: Journal of affective disorders. 296, p. 126-129 4 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• Anxiety, Mental Stress, and Sudden Cardiac Arrest: Epidemiology, Possible Mechanisms and Future Research

  Batelaan, N. M., Seldenrijk, A., van den Heuvel, O. A., van Balkom, A. J. L. M., Kaiser, A., Reneman, L. & Tan, H. L., 3 Feb 2022, In: Frontiers in psychiatry. 12, 813518.

  Research output: Contribution to Journal › Review article › Academic › peer-review

  Open Access

• Anxiety and Depressive Symptoms during the COVID-19 Emergency Period: A Comparative Cross-Sectional Study in Professional Football

  Gouttebarge, V., Ahmad, I., Mountjoy, M., Rice, S. & Kerkhoffs, G., 1 Jan 2022, In: Clinical journal of sport medicine. 32, 1, p. 21-27 7 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

• Aortic root diameter is associated with HLA-B27: identifying the patient with ankylosing spondylitis at risk for aortic valve regurgitation

  Baniaamam, M., Heslinga, S. C., Konings, T. C., Handoko, M. L., Kamp, O., van Halm, V. P., van der Horst-Bruinsma, I. E. & Nurmohamed, M. T., Apr 2022, In: Rheumatology International. 42, 4, p. 683-688 6 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• A Pharmacy-Based eHealth Intervention Promoting Correct Use of Medication in Patients With Asthma and COPD: Nonrandomized Pre-Post Study

  Schnoor, K., Versluis, A., Bakema, R., van Luenen, S., Kooij, M. J., van den Heuvel, J. M., Teichert, M., Honkoop, P. J., van Boven, J. F. M., Chavannes, N. H. & Aardoom, J. J., 1 Jun 2022, In: Journal of medical Internet research. 24, 6, p. e32396 e32396.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• A phase Ib/II study of regorafenib and paclitaxel in patients with beyond first-line advanced esophagogastric carcinoma (REPEAT)

  Stroes, C. I., Schokker, S., Khurshed, M., van der Woude, S. O., Mathôt, R. A. A., Slingerland, M., de Vos-Geelen, J., Zucchetti, M., Matteo, C., van Dijk, E., Ylstra, B., Thijssen, V., Derks, S., Godefa, T., Dijksterhuis, W., Breimer, G. E., van Delden, O. M., Verhoeven, R. H. A., Meijer, S. L., Bijlsma, M. F. & 1 others, van Laarhoven, H. W. M., 2022, In: Therapeutic advances in medical oncology. 14

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• A phase II, Multicentre, Randomised, Double-Blind, Placebo-controlled Study to Evaluate Safety, Tolerability, and Efficacy of Amiselimod in Patients with Moderate to Severe Active Crohn's Disease

  D'Haens, G., Danese, S., Davies, M., Watanabe, M. & Hibi, T., 1 May 2022, In: Journal of Crohn's and Colitis. 16, 5, p. 746-756 11 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

• Apical-out airway organoids as a platform for studying viral infections and screening for antiviral drugs

  Stroulios, G., Brown, T., Moreni, G., Kondro, D., Dei, A., Eaves, A., Louis, S., Hou, J., Chang, W., Pajkrt, D., Wolthers, K. C., Sridhar, A. & Simmini, S., 1 Dec 2022, In: Scientific reports. 12, 1, 7673.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• A pictorial account of the human embryonic heart between 3.5 and 8 weeks of development

  Hikspoors, J. P. J. M., Kruepunga, N., Mommen, G. M. C., Köhler, S. E., Anderson, R. H. & Lamers, W. H., 1 Dec 2022, In: Communications Biology. 5, 1, 226.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• Apolipoprotein A1 deficiency in mice primes bone marrow stem cells for T cell lymphopoiesis

  Ouweneel, A. B., Reiche, M. E., Snip, O. S. C., Wever, R., van der Wel, E. J., Schaftenaar, F. H., Kauerova, S., Lutgens, E., van Eck, M. & Hoekstra, M., 1 Mar 2022, In: Journal of Cell Science. 135, 5, jcs25890.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• Apolipoprotein E derived from CD11c+ cells ameliorates atherosclerosis

  Sauter, M., Sauter, R. J., Nording, H., Lin, C., Olbrich, M., Autenrieth, S., Gleissner, C., Thunemann, M., Otero, N., Lutgens, E., Aherrahrou, Z., Wolf, D., Zender, L., Meuth, S., Feil, R. & Langer, H. F., 21 Jan 2022, In: iScience. 25, 1, 103677.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• Apolipoprotein L1 is increased in frontotemporal lobar degeneration post-mortem brain but not in ante-mortem cerebrospinal fluid

  Hok-A-Hin, Y. S., Dijkstra, A. A., Rábano, A., Hoozemans, J. J., Castillo, L., Seelaar, H., van Swieten, J. C., Pijnenburg, Y. A. L., Teunissen, C. E., Del Campo, M. & Seelaar, H., 1 Oct 2022, In: Neurobiology of Disease. 172, p. 105813 105813.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• Apophyseal Avulsion of the Rectus Femoris Tendon Origin in Adolescent Soccer Players

  Weel, H., Joosten, A. J. P. & van Bergen, C. J. A., 1 Jul 2022, In: Children. 9, 7, 1016.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• A population-based study in resected esophageal or gastroesophageal junction cancer aligned with CheckMate 577

  Pape, M., Vissers, P. A. J., Beerepoot, L. V., van Berge Henegouwen, M. I., Lagarde, S. M., Mook, S., Moehler, M., van Laarhoven, H. W. M. & Verhoeven, R. H. A., 1 Feb 2022, In: Therapeutic advances in medical oncology. 14

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• A population-based study in synchronous versus metachronous metastatic esophagogastric adenocarcinoma

  Pape, M., Vissers, P. A. J., Bertwistle, D., McDonald, L., Slingerland, M., Haj Mohammad, N., Beerepoot, L. V., Ruurda, J. P., Nieuwenhuijzen, G. A. P., Jeene, P. M., van Laarhoven, H. W. M. & Verhoeven, R. H. A., 1 Mar 2022, In: Therapeutic advances in medical oncology. 14

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• A population-based study of the epidemiology of oral squamous cell carcinoma in the Netherlands 1989–2018, with emphasis on young adults

  Al-Jamaei, A. A. H., van Dijk, B. A. C., Helder, M. N., Forouzanfar, T., Leemans, C. R. & de Visscher, J. G. A. M., Jan 2022, In: International Journal of Oral and Maxillofacial Surgery. 51, 1, p. 1-9 9 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• A population-based study on treatment and outcomes in patients with gastric adenocarcinoma diagnosed with distant interval metastases

  Dijksterhuis, W. P. M., Kroese, T. E., Verhoeven, R. H. A., van Rossum, P. S. N., Mook, S., Haj Mohammad, N., Hulshof, M. C. C. M., Gisbertz, S. S., Ruurda, J. P., van Oijen, M. G. H., van Hillegersberg, R. & van Laarhoven, H. W. M., 2022, (E-pub ahead of print) In: European journal of surgical oncology.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• App-based COVID-19 syndromic surveillance and prediction of hospital admissions in COVID Symptom Study Sweden

  Kennedy, B., Fitipaldi, H., Hammar, U., Maziarz, M., Tsereteli, N., Oskolkov, N., Varotsis, G., Franks, C. A., Nguyen, D., Spiliopoulos, L., Adami, H-O., Björk, J., Engblom, S., Fall, K., Grimby-Ekman, A., Litton, J-E., Martinell, M., Oudin, A., Sjöström, T., Timpka, T. & 16 others, Sudre, C. H., Graham, M. S., du Cadet, J. L., Chan, A. T., Davies, R., Ganesh, S., May, A., Ourselin, S. B., Pujol, J. C., Selvachandran, S., Wolf, J., Spector, T. D., Steves, C. J., Gomez, M. F., Franks, P. W. & Fall, T., 1 Dec 2022, In: Nature communications. 13, 1, 2110.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• Applicability and Validity of an e-Health Tool for the Appropriate Referral and Selection of Patients With Chronic Pain for Spinal Cord Stimulation: Results From a European Retrospective Study

  Thomson, S., Huygen, F., Prangnell, S., Baranidharan, G., Belaïd, H., Billet, B., Eldabe, S., de Carolis, G., Demartini, L., Gatzinsky, K., Kallewaard, J. W., Paroli, M., Winkelmüller, M., Helsen, N. & Stoevelaar, H., 2022, (E-pub ahead of print) In: Neuromodulation.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• Application of local gentamicin in the treatment of deep sternal wound infection: a randomized controlled trial

  Vos, R. J., van Putte, B. P., de Mol, B. A. J. M., Hoogewerf, M., Mandigers, T. J. & Kloppenburg, G. T. L., 1 May 2022, In: European Journal of Cardio-thoracic Surgery. 61, 5, p. 1135-1141

  Research output: Contribution to Journal › Article › Academic › peer-review

• Application of SHAP values for inferring the optimal functional form of covariates in pharmacokinetic modeling

  OPTI-CLOT study group and SYMPHONY consortium, 2022, (E-pub ahead of print) In: CPT: pharmacometrics & systems pharmacology.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• Application of the International IgA Nephropathy Prediction Tool one or two years post-biopsy

  International IgA Nephropathy Network, Jul 2022, In: Kidney international. 102, 1, p. 160-172 13 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• Applying the HEART score is safe and saves

  Appelman, Y. & Doevendans, P., 1 Jul 2022, In: Netherlands Heart Journal. 30, 7-8, p. 350-351 2 p.

  Research output: Contribution to Journal › Comment / Letter to the editor › Academic

  Open Access

• Approaches to Surgical Debridement in Necrotizing Soft Tissue Infections: Outcomes of an Animated, Interactive Survey

  Suijker, J., Hofmans, F. A. C., van Zuijlen, P. P. M., Cense, H. A., Bonjer, H. J. & Vries, A. M., May 2022, In: World Journal of Surgery. 46, 5, p. 1051-1058 8 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• Appropriateness of Medical and Surgical Treatments for Chronic Pouchitis Using RAND/UCLA Appropriateness Methodology

  Syal, G., Sparrow, M. P., Velayos, F., Cheifetz, A. S., Devlin, S., Irving, P. M., Kaplan, G. G., Raffals, L. E., Ullman, T., Gecse, K. B., Fleshner, P. R., Lightner, A. L., Siegel, C. A. & Melmed, G. Y., 2022, (E-pub ahead of print) In: Digestive diseases and sciences.

  Research output: Contribution to Journal › Article › Academic › peer-review

• Approximate likelihood-based estimation method of multiple-type pathogen interactions: An application to longitudinal pneumococcal carriage data

  Man, I., Bogaards, J. A., Makwana, K., Trzciński, K. & Auranen, K., 15 Mar 2022, In: Statistics in medicine. 41, 6, p. 981-993 13 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• A pragmatic approach for implementation of value-based healthcare in Amsterdam UMC, the Netherlands

  Heijsters, F. A. C. J., van Breda, F. G. F., van Nassau, F., van der Steen, M. K. J., ter Wee, P. M., Mullender, M. G. & de Bruijne, M. C., 1 Dec 2022, In: BMC health services research. 22, 1, 550.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• A Prediction Model for Falls in Community-Dwelling Older Adults in Podiatry Practices

  van Gulick, D. J. J., Perry, S. I. B., van der Leeden, M., van Beek, J. G. M., Lucas, C. & Stuiver, M. M., 2022, (E-pub ahead of print) In: Gerontology.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• A preoperative prediction model for anastomotic leakage after rectal cancer resection based on 13.175 patients

  Dutch ColoRectal Audit Group, 2022, (E-pub ahead of print) In: European journal of surgical oncology.

  Research output: Contribution to Journal › Article › Academic › peer-review

• A primer on obesity-related cardiomyopathy

  Samson, W. K., Yosten, G. L. C. & Remme, C. A., 1 Jan 2022, In: Physiological Reviews. 102, 1, p. 1-6 6 p.

  Research output: Contribution to Journal › Editorial › Academic › peer-review

  Open Access

• A progressive three-state model to estimate time to cancer: a likelihood-based approach

  Akwiwu, E. U., Klausch, T., Jodal, H. C., Carvalho, B., Løberg, M., Kalager, M., Berkhof, J. & H. Coupé, V. M., 1 Dec 2022, In: BMC Medical Research Methodology. 22, 1, 179.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• A Prospective Five-Year Follow-up After peg-Interferon Plus Nucleotide Analogue Treatment or no Treatment in HBeAg Negative Chronic Hepatitis B Patients

  Erken, R., Loukachov, V. V., de Niet, A., Jansen, L., Stelma, F., Helder, J. T., Peters, M. W., Zaaijer, H. L., Kootstra, N. A., Willemse, S. B. & Reesink, H. W., 1 May 2022, In: Journal of Clinical and Experimental Hepatology. 12, 3, p. 735-744 10 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• A Prospective Multicenter Comparison Study of Risk-adapted Ultrasound-directed and Magnetic Resonance Imaging–directed Diagnostic Pathways for Suspected Prostate Cancer in Biopsy-naïve Men

  MR-PROPER Study Group, Sep 2022, In: European urology. 82, 3, p. 318-326 9 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• A qualitative study on the challenges health care professionals face when caring for adolescents and young adults with an uncertain and/or poor cancer prognosis

  Burgers, V. W. G., van den Bent, M. J., Darlington, A. S. E., Gualthérie van Weezel, A. E., Compter, A., Tromp, J. M., Lalisang, R. I., Kouwenhoven, M. C. M., Dirven, L., Harthoorn, N. C. G. L., Troost-Heijboer, C. A., Husson, O. & van der Graaf, W. T. A., 1 Jun 2022, In: ESMO OPEN. 7, 3, 100476.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• A Quality Checklist for Responsible Conduct of Research (RCR) Education: A proposal to complement the Predictive Modeling Tool

  Krom, A. & van den Hoven, M., 2022, In: Accountability in Research. 29, 1, p. 26-44 19 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• A randomised phase II study of osimertinib and bevacizumab versus osimertinib alone as second-line targeted treatment in advanced NSCLC with confirmed EGFR and acquired T790M mutations: the European Thoracic Oncology Platform (ETOP 10-16) BOOSTER trial

  ETOP 10-16 BOOSTER Collaborators, Feb 2022, In: Annals of oncology : official journal of the European Society for Medical Oncology. 33, 2, p. 181-192 12 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

• A Randomized, Open-Label Phase II Study Evaluating Emibetuzumab Plus Erlotinib and Emibetuzumab Monotherapy in MET Immunohistochemistry Positive NSCLC Patients with Acquired Resistance to Erlotinib

  Camidge, D. R., Moran, T., Demedts, I., Grosch, H., Mileham, K., Molina, J., Juan-Vidal, O., Bepler, G., Goldman, J. W., Park, K., Wallin, J., Wijayawardana, S. R., Wang, X. A., Wacheck, V. & Smit, E., Jun 2022, In: Clinical lung cancer. 23, 4, p. 300-310 11 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

• A randomized, placebo-controlled clinical trial evaluating olipudase alfa enzyme replacement therapy for chronic acid sphingomyelinase deficiency (ASMD) in adults: One-year results

  Wasserstein, M., Lachmann, R., Hollak, C., Arash-Kaps, L., Barbato, A., Gallagher, R. C., Giugliani, R., Guelbert, N. B., Ikezoe, T., Lidove, O., Mabe, P., Mengel, E., Scarpa, M., Senates, E., Tchan, M., Villarrubia, J., Chen, Y., Furey, S., Thurberg, B. L., Zaher, A. & 1 others, Kumar, M., 1 Jul 2022, In: Genetics in Medicine. 24, 7, p. 1425-1436 12 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• A Randomized Controlled Trial on the Effects of a 12-Week High- vs. Low-Intensity Exercise Intervention on Hippocampal Structure and Function in Healthy, Young Adults

  Kaiser, A., Reneman, L., Solleveld, M. M., Coolen, B. F., Scherder, E. J. A., Knutsson, L., Bjørnerud, A., van Osch, M. J. P., Wijnen, J. P., Lucassen, P. J. & Schrantee, A., 21 Jan 2022, In: Frontiers in psychiatry. 12, 15 p., 780095.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• A randomized phase-II study of reirradiation and hyperthermia versus reirradiation and hyperthermia plus chemotherapy for locally recurrent breast cancer in previously irradiated area

  Schouten, D., van Os, R., Westermann, A. M., Crezee, H., van Tienhoven, G., Kolff, W. M. & Bins, A. D., 2022, In: Acta oncologica. 61, 4, p. 441-448 8 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• A randomized trial predicting response to cognitive rehabilitation in multiple sclerosis: Is there a window of opportunity?

  Prouskas, S. E., Schoonheim, M. M., Huiskamp, M., Steenwijk, M. D., Gehring, K., Barkhof, F., de Jong, B. A., Sitskoorn, M. M., Geurts, J. J. G. & Hulst, H. E., 28 Jun 2022, (E-pub ahead of print) In: MULTIPLE SCLEROSIS JOURNAL.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• Are Brain and Cognitive Reserve Shaped by Early Life Circumstances?

  de Rooij, S. R., 16 Jun 2022, In: Frontiers in neuroscience. 16, 825811.

  Research output: Contribution to Journal › Review article › Academic › peer-review

  Open Access

• Are national treatment guidelines for falciparum malaria in line with WHO recommendations and is antimalarial resistance taken into consideration? – A review of guidelines in non-endemic countries

  Visser, M. T., Zonneveld, R., Peto, T. J., van Vugt, M., Dondorp, A. M. & van der Pluijm, R. W., Feb 2022, In: Tropical Medicine & International Health. 27, 2, p. 129-136 8 p.

  Research output: Contribution to Journal › Review article › Academic › peer-review

  Open Access

• Are periodontitis, dental caries and xerostomia more frequently present in recreational ecstasy users?

  van Kempen, E. E. J., de Visscher, J. G. A. M. & Brand, H. S., 25 Mar 2022, In: British dental journal. 232, 6, p. 389-395 7 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• Are personality disorders in bipolar patients more frequent in the US than Europe?

  Post, R. M., Leverich, G. S., McElroy, S. L., Kupka, R., Suppes, T., Altshuler, L. L., Nolen, W. A., Frye, M. A., Keck, P. E., Grunze, H. & Rowe, M., 1 May 2022, In: European neuropsychopharmacology. 58, p. 47-54 8 p.

  Research output: Contribution to Journal › Article › Academic › peer-review