A comparison of the in vitro cytotoxicity of daunorubicin and liposomal daunorubicin in pediatric acute leukemia

Bianca F. Goemans, Christian M. Zwaan, Dirk Reinhardt, Brenda E.S. Gibson, K. Hählen, Gert Jan L. Kaspers

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)


Anthracyclines are effective in the treatment of leukemia, but their use is limited because of cardiotoxicity. Liposomal daunorubicin (L-DNR) is potentially less cardiotoxic than daunorubicin (DNR). We compared in vitro cytotoxicity in pediatric acute leukemia samples and found no significant differences between cytotoxicity of DNR and L-DNR.

Original languageEnglish
Pages (from-to)1573-1574
Number of pages2
Issue number11
Publication statusPublished - Nov 2006


  • Cardiotoxicity
  • Drug sensitivity
  • Liposomal daunombicin
  • Pediatric acute leukemia

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