A portable gamma-camera for intraoperative detection of sentinel nodes in the head and neck region

Lenka Vermeeren; Renato A. Valdés Olmos; W. Martin C. Klop; Alfons J. M. Balm; Michiel W. M. van den Brekel

doi:https://doi.org/10.2967/jnumed.109.071407

A portable gamma-camera for intraoperative detection of sentinel nodes in the head and neck region

Lenka Vermeeren, Renato A. Valdés Olmos, W. Martin C. Klop, Alfons J. M. Balm, Michiel W. M. van den Brekel

Research output: Contribution to journal › Article › Academic › peer-review

111 Citations (Scopus)

Abstract

We introduced and evaluated a portable gamma-camera for intraoperative visualization of sentinel nodes in the head and neck region. METHODS: Planar lymphoscintigraphy and SPECT/CT were performed after peritumoral injection of (99m)Tc-nanocolloid in 25 patients (head and neck melanoma or oral cavity carcinoma). Sentinel nodes were localized intraoperatively with a portable gamma-camera and a hand-held gamma-probe. The portable gamma-camera was used to determine the distribution of remaining radioactivity after excision of the sentinel nodes. RESULTS: The portable gamma-camera visualized all 70 preoperatively identified sentinel nodes. Sentinel nodes at difficult sites could be localized more efficiently, and in 6 patients, 9 additional nodes (1 tumor-positive) were identified with the portable gamma-camera after excision. CONCLUSION: Intraoperative identification of sentinel nodes in the head and neck region with a portable gamma-camera is feasible and might lead to detection of more sentinel nodes

Original language	English
Pages (from-to)	700-703
Journal	Journal of nuclear medicine
Volume	51
Issue number	5
DOIs	https://doi.org/10.2967/jnumed.109.071407
Publication status	Published - 2010

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https://doi.org/10.2967/jnumed.109.071407

Cite this

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title = "A portable gamma-camera for intraoperative detection of sentinel nodes in the head and neck region",

abstract = "We introduced and evaluated a portable gamma-camera for intraoperative visualization of sentinel nodes in the head and neck region. METHODS: Planar lymphoscintigraphy and SPECT/CT were performed after peritumoral injection of (99m)Tc-nanocolloid in 25 patients (head and neck melanoma or oral cavity carcinoma). Sentinel nodes were localized intraoperatively with a portable gamma-camera and a hand-held gamma-probe. The portable gamma-camera was used to determine the distribution of remaining radioactivity after excision of the sentinel nodes. RESULTS: The portable gamma-camera visualized all 70 preoperatively identified sentinel nodes. Sentinel nodes at difficult sites could be localized more efficiently, and in 6 patients, 9 additional nodes (1 tumor-positive) were identified with the portable gamma-camera after excision. CONCLUSION: Intraoperative identification of sentinel nodes in the head and neck region with a portable gamma-camera is feasible and might lead to detection of more sentinel nodes",

author = "Lenka Vermeeren and {Vald{\'e}s Olmos}, {Renato A.} and Klop, {W. Martin C.} and Balm, {Alfons J. M.} and {van den Brekel}, {Michiel W. M.}",

year = "2010",

doi = "https://doi.org/10.2967/jnumed.109.071407",

language = "English",

volume = "51",

pages = "700--703",

journal = "Journal of nuclear medicine",

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T1 - A portable gamma-camera for intraoperative detection of sentinel nodes in the head and neck region

AU - Vermeeren, Lenka

AU - Valdés Olmos, Renato A.

AU - Klop, W. Martin C.

AU - Balm, Alfons J. M.

AU - van den Brekel, Michiel W. M.

PY - 2010

Y1 - 2010

N2 - We introduced and evaluated a portable gamma-camera for intraoperative visualization of sentinel nodes in the head and neck region. METHODS: Planar lymphoscintigraphy and SPECT/CT were performed after peritumoral injection of (99m)Tc-nanocolloid in 25 patients (head and neck melanoma or oral cavity carcinoma). Sentinel nodes were localized intraoperatively with a portable gamma-camera and a hand-held gamma-probe. The portable gamma-camera was used to determine the distribution of remaining radioactivity after excision of the sentinel nodes. RESULTS: The portable gamma-camera visualized all 70 preoperatively identified sentinel nodes. Sentinel nodes at difficult sites could be localized more efficiently, and in 6 patients, 9 additional nodes (1 tumor-positive) were identified with the portable gamma-camera after excision. CONCLUSION: Intraoperative identification of sentinel nodes in the head and neck region with a portable gamma-camera is feasible and might lead to detection of more sentinel nodes

AB - We introduced and evaluated a portable gamma-camera for intraoperative visualization of sentinel nodes in the head and neck region. METHODS: Planar lymphoscintigraphy and SPECT/CT were performed after peritumoral injection of (99m)Tc-nanocolloid in 25 patients (head and neck melanoma or oral cavity carcinoma). Sentinel nodes were localized intraoperatively with a portable gamma-camera and a hand-held gamma-probe. The portable gamma-camera was used to determine the distribution of remaining radioactivity after excision of the sentinel nodes. RESULTS: The portable gamma-camera visualized all 70 preoperatively identified sentinel nodes. Sentinel nodes at difficult sites could be localized more efficiently, and in 6 patients, 9 additional nodes (1 tumor-positive) were identified with the portable gamma-camera after excision. CONCLUSION: Intraoperative identification of sentinel nodes in the head and neck region with a portable gamma-camera is feasible and might lead to detection of more sentinel nodes

U2 - https://doi.org/10.2967/jnumed.109.071407

DO - https://doi.org/10.2967/jnumed.109.071407

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SN - 0161-5505

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JO - Journal of nuclear medicine

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