Activity of daptomycin against Listeria monocytogenes isolates from cerebrospinal fluid

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Abstract

We tested the activity of daptomycin against 76 Listeria monocytogenes isolates from cerebrospinal fluid by broth dilution and Etest methods. For the broth dilution method, the MIC range was 1.0 to 8.0 and the MIC at which 90% of the isolates tested were inhibited (MIC(90)) was 4.0 mg/liter. For the Etest method, the MIC range was 1.0 to 4.0 and the MIC(90) was 4.0 mg/liter. Presently, daptomycin cannot be recommended for the treatment of L. monocytogenes meningitis
Original languageEnglish
Pages (from-to)1850-1851
JournalAntimicrobial Agents and Chemotherapy
Volume52
Issue number5
DOIs
Publication statusPublished - 2008

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