TY - JOUR
T1 - Acute Community-Acquired Bacterial Meningitis
AU - Figueiredo, Ana Helena A.
AU - Brouwer, Matthijs C.
AU - van de Beek, Diederik
PY - 2018
Y1 - 2018
N2 - Community-acquired bacterial meningitis remains a disease with high impact. The epidemiology of this disease changed substantiality to large-scale introduction of conjugated vaccines. Streptococcus pneumoniae and Neisseria meningitidis are the main causative pathogens outside the neonatal age. Clinical presentation of patients with bacterial meningitis varies depending on age and underlying condition. A delay in diagnosis and antimicrobial therapy has been associated with increased risk of adverse clinical outcome. Empirical antibiotic treatment should be based on common bacterial species that cause the disease according to the patient's age group or clinical setting and on local antibiotic susceptibility patterns of the predominant pathogens.
AB - Community-acquired bacterial meningitis remains a disease with high impact. The epidemiology of this disease changed substantiality to large-scale introduction of conjugated vaccines. Streptococcus pneumoniae and Neisseria meningitidis are the main causative pathogens outside the neonatal age. Clinical presentation of patients with bacterial meningitis varies depending on age and underlying condition. A delay in diagnosis and antimicrobial therapy has been associated with increased risk of adverse clinical outcome. Empirical antibiotic treatment should be based on common bacterial species that cause the disease according to the patient's age group or clinical setting and on local antibiotic susceptibility patterns of the predominant pathogens.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85053760205&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/30366556
U2 - https://doi.org/10.1016/j.ncl.2018.06.007
DO - https://doi.org/10.1016/j.ncl.2018.06.007
M3 - Review article
C2 - 30366556
SN - 0733-8619
VL - 36
SP - 809
EP - 820
JO - Neurologic Clinics
JF - Neurologic Clinics
IS - 4
ER -