Innate killers at work: Strategies to exploit neutrophils for cancer treatment

P. Martinez Sanz

Innate killers at work: Strategies to exploit neutrophils for cancer treatment

Research output: PhD Thesis › Phd-Thesis - Research and graduation internal

Abstract

Neutrophils are known to have opposing roles in a cancer setting. Depending on the circumstances they can either promote tumor progression via immunosuppressive mechanisms, or eliminate cancer cells when triggered by an antigen-targeting antibody via antibody-dependent cellular cytotoxicity. In the present thesis we highlight different ways in which the neutrophil’s anti-

Original language	English
Qualification	Doctor of Philosophy
Awarding Institution	University of Amsterdam
Supervisors/Advisors	Kuijpers, Taco, Supervisor Matlung, Hanke L., Co-supervisor, External person Tytgat, Godelieve Am, Co-supervisor, External person Kuijpers, T.W., Supervisor, External person Tytgat, G.A.M., Co-supervisor, External person
Award date	19 Oct 2023
Print ISBNs	9789464833539
Publication status	Published - 2023

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title = "Innate killers at work: Strategies to exploit neutrophils for cancer treatment",

abstract = "Neutrophils are known to have opposing roles in a cancer setting. Depending on the circumstances they can either promote tumor progression via immunosuppressive mechanisms, or eliminate cancer cells when triggered by an antigen-targeting antibody via antibody-dependent cellular cytotoxicity. In the present thesis we highlight different ways in which the neutrophil{\textquoteright}s anti-",

author = "{Martinez Sanz}, P.",

year = "2023",

language = "English",

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type = "Phd-Thesis - Research and graduation internal",

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TY - THES

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T2 - Strategies to exploit neutrophils for cancer treatment

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Y1 - 2023

N2 - Neutrophils are known to have opposing roles in a cancer setting. Depending on the circumstances they can either promote tumor progression via immunosuppressive mechanisms, or eliminate cancer cells when triggered by an antigen-targeting antibody via antibody-dependent cellular cytotoxicity. In the present thesis we highlight different ways in which the neutrophil’s anti-

AB - Neutrophils are known to have opposing roles in a cancer setting. Depending on the circumstances they can either promote tumor progression via immunosuppressive mechanisms, or eliminate cancer cells when triggered by an antigen-targeting antibody via antibody-dependent cellular cytotoxicity. In the present thesis we highlight different ways in which the neutrophil’s anti-

UR - https://pure.uva.nl/ws/files/140487368/Licence_Agreement_co_signed_.pdf

M3 - Phd-Thesis - Research and graduation internal

SN - 9789464833539

ER -

Innate killers at work: Strategies to exploit neutrophils for cancer treatment

Abstract

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