@article{17e915fcdf4c4facbd40a4b3578f9a3b,
title = "Alcohol use as a predictor of the course of major depressive disorder: a prospective population-based study",
abstract = "Aims There are indications that problematic alcohol use may negatively impact the course of major depressive disorder (MDD). However, most studies on alcohol use and adverse MDD outcomes are conducted amongst MDD populations with (severe) alcohol use disorder in psychiatric treatment settings. Therefore, it remains unclear whether these results can be generalised to the general population. In light of this, we examined the longitudinal relationship between alcohol use and MDD persistence after a 3-year follow-up amongst people with MDD from the general population. Methods Data were derived from the Netherlands Mental Health Survey and Incidence Study-2 (NEMESIS-2), a psychiatric epidemiological prospective study comprising four waves amongst the adult Dutch general population (n = 6.646). The study sample (n = 642) consisted of those with 12-month MDD who participated at the follow-up wave. The outcome was 12-month MDD persistence after the 3-year follow-up, which was assessed via the Composite International Diagnostic Interview version 3.0.",
keywords = "alcohol abuse, depression, epidemiology, mental health, prospective study",
author = "Schouten, {Maria J. E.} and {ten Have}, Margreet and Marlous Tuithof and {de Graaf}, Ron and Dekker, {Jack J. M.} and Goudriaan, {Anna E.} and Matthijs Blankers",
note = "Funding Information: NEMESIS-2 was conducted by the Netherlands Institute of Mental Health and Addiction (Trimbos Institute) in Utrecht. Financial support was received from the Ministry of Health, Welfare and Sport, with supplementary support from both the Netherlands Organization for Health Research and Development (ZonMw) and the Genetic Risk and Outcome of Psychosis (GROUP) investigators. This study was carried out in the context of a ZonMw funded project (grant number: 636310009) on depression with comorbid alcohol misuse (awarded to MB., AG., JD). The funding sources played no further role in terms of the study design, the collection, analysis and interpretation of data, nor in the writing of the report or the decision to submit the article for publication. Publisher Copyright: {\textcopyright} 7 drinks; reference), at-risk drinking (women 8-13 drinks, men 8-20 drinks) and high-risk drinking (women",
year = "2023",
month = feb,
day = "27",
doi = "https://doi.org/10.1017/S2045796023000070",
language = "English",
volume = "32",
pages = "e14",
journal = "Epidemiology and Psychiatric Sciences",
issn = "2045-7960",
publisher = "Cambridge University Press",
}