TY - JOUR
T1 - Anastomotic leakage after esophagectomy for esophageal cancer: Definitions, diagnostics, and treatment
AU - Fabbi, M.
AU - Hagens, E. R. C.
AU - van Berge Henegouwen, M. I.
AU - Gisbertz, S. S.
N1 - Publisher Copyright: © 2020 The Author(s) 2020. Published by Oxford University Press on behalf of International Society for Diseases of the Esophagus.
PY - 2021/1/1
Y1 - 2021/1/1
N2 - Anastomotic leakage is one of the most severe complications after esophagectomy and is associated with increased postoperative morbidity and mortality. Several projects ranging from small retrospective studies to large collaborations have aimed to identify potential pre- and perioperative risk factors and to improve the diagnostic processes and management. Despite the increase in available literature, many aspects of anastomotic leakage are still debated, without the existence of widely accepted guidelines. The purpose of this review is to provide a cutting edge overview of the recent literature regarding the definition and classification of anastomotic leakage, risk factors, novel diagnostic modalities, and emerging therapeutic options for treatment and prevention of anastomotic leakage following esophagectomy.
AB - Anastomotic leakage is one of the most severe complications after esophagectomy and is associated with increased postoperative morbidity and mortality. Several projects ranging from small retrospective studies to large collaborations have aimed to identify potential pre- and perioperative risk factors and to improve the diagnostic processes and management. Despite the increase in available literature, many aspects of anastomotic leakage are still debated, without the existence of widely accepted guidelines. The purpose of this review is to provide a cutting edge overview of the recent literature regarding the definition and classification of anastomotic leakage, risk factors, novel diagnostic modalities, and emerging therapeutic options for treatment and prevention of anastomotic leakage following esophagectomy.
KW - anastomotic dehiscence
KW - anastomotic leakage
KW - esophageal cancer
KW - esophageal resection
KW - gastric tube reconstruction
UR - http://www.scopus.com/inward/record.url?scp=85100070377&partnerID=8YFLogxK
U2 - https://doi.org/10.1093/dote/doaa039
DO - https://doi.org/10.1093/dote/doaa039
M3 - Article
C2 - 32476017
SN - 1120-8694
VL - 34
JO - Diseases of the Esophagus
JF - Diseases of the Esophagus
IS - 1
M1 - doaa039
ER -