@article{ccc408498940488cbf1881abb0acc424,
title = "Antirheumatic drugs for cardiovascular disease prevention: The case for colchicine",
abstract = "We summarised four pivotal Randomised Controlled Trials (RCTs) with antirheumatic drugs on the secondary prevention of cardiovascular events. The favourable effects of canakinumab and colchicine confirm (low-grade) inflammation as an independent risk factor for cardiovascular events. While colchicine might be the first drug in the clinic, we expect that this is only the first in a future series of anti-inflammatory drugs used in secondary prevention of cardiovascular events.",
keywords = "antirheumatic agents, cardiovascular diseases, interleukin 1 receptor antagonist protein",
author = "Willem Lems and Maarten Boers and {van Vollenhoven}, {Ronald F.} and Mike Nurmohamed",
note = "Funding Information: Competing interests WL: received fees for lectures and advisory boards from Amgen, Eli Lilly, UCB, Pfizer, Galapagos and Curaphar. RFvV: research support (institutional grants): BMS, GSK, Lilly and UCB; support for educational programs (institutional grants): Pfizer and Roche; consultancy, for which institutional and/or personal honoraria were received: AbbVie, AstraZeneca, Biogen, Biotest, Celgene, Galapagos, Gilead, Janssen, Pfizer, Sanofi, Servier and UCB and speaker, for which institutional and/or personal honoraria were received: AbbVie, Galapagos, Janssen, Pfizer and UCB. MN: consulting fees from AbbVie, Celgene, Celltrion, Eli Lilly, Janssen and Sanofi, speaker{\textquoteright}s fees from AbbVie, Bristol-Myers Squibb, Eli Lilly, Roche and Sanofi and research funding from AbbVie, Bristol-Myers Squibb, Celgene, Eli Lilly, Janssen, MSD, Mundipharma, Novartis, Pfizer, Roche and Sanofi. Publisher Copyright: {\textcopyright} 2021 BMJ Publishing Group. All rights reserved. Copyright: Copyright 2021 Elsevier B.V., All rights reserved.",
year = "2021",
month = mar,
day = "16",
doi = "https://doi.org/10.1136/rmdopen-2020-001560",
language = "English",
volume = "7",
journal = "RMD OPEN",
issn = "2056-5933",
publisher = "BMJ Publishing Group",
number = "1",
}