TY - JOUR
T1 - APOE-ε4 allele for the diagnosis of Alzheimer's and other dementia disorders in people with mild cognitive impairment in a secondary care setting
AU - Elias-Sonnenschein, Lyzel S.
AU - Viechtbauer, Wolfgang
AU - Ramakers, Inez
AU - Ukoumunne, Obioha
AU - Verhey, Frans R.J.
AU - Visser, Pieter Jelle
PY - 2014/1/31
Y1 - 2014/1/31
N2 - This is the protocol for a review and there is no abstract. The objectives are as follows: Our primary objective is to determine the diagnostic accuracy of the APOE-ε4 allele in detecting AD dementia and other types of dementia in people with MCI in a secondary care setting. Our secondary objective is to investigate the following potential sources of heterogeneity of test accuracy, where reported: characteristics of participants, namely, baseline MMSE score, age, and gender; APOE-ε4 background prevalence; MCI definition; length of follow-up; and reference standards.
AB - This is the protocol for a review and there is no abstract. The objectives are as follows: Our primary objective is to determine the diagnostic accuracy of the APOE-ε4 allele in detecting AD dementia and other types of dementia in people with MCI in a secondary care setting. Our secondary objective is to investigate the following potential sources of heterogeneity of test accuracy, where reported: characteristics of participants, namely, baseline MMSE score, age, and gender; APOE-ε4 background prevalence; MCI definition; length of follow-up; and reference standards.
UR - http://www.scopus.com/inward/record.url?scp=85041852515&partnerID=8YFLogxK
U2 - https://doi.org/10.1002/14651858.CD010950
DO - https://doi.org/10.1002/14651858.CD010950
M3 - Article
SN - 1464-780X
VL - 2014
JO - Cochrane Library
JF - Cochrane Library
IS - 1
M1 - CD010950
ER -