Autoantibodies against type I interferons are associated with multi-organ failure in COVID-19 patients

TY - JOUR

T1 - Autoantibodies against type I interferons are associated with multi-organ failure in COVID-19 patients

AU - with the Amsterdam U.M.C. COVID-19 Biobank Investigators

AU - Koning, Rutger

AU - Bastard, Paul

AU - Casanova, Jean-Laurent

AU - Brouwer, Matthijs C

AU - van de Beek, Diederik

AU - Study group members AMC, null

AU - Wiersinga, W. Joost

AU - de Bree, Godelieve J.

AU - Geerlings, Suzanne E.

AU - Goorhuis, Bram

AU - Grobusch, Martin P.

AU - Harris, Vanessa C.

AU - Hermans, Sabine M.

AU - Hovius, Joppe W. R.

AU - Nellen, Jeanine

AU - van der Poll, Tom

AU - Prins, Jan M.

AU - Stijnis, Cornelis S.

AU - van der Valk, Marc

AU - van Vugt, Michele

AU - Hollmann, Markus W.

AU - Preckel, Prof. dr. , Benedikt

AU - Veelo, Denise P.

N1 - Funding Information: The Amsterdam U.M.C. COVID-19 Biobank Investigators Michiel van Agtmael2, Anne Geke Algera1, Brent Appelman2, Frank van Baarle1, Diane Bax3, Martijn Beudel4, Harm Jan Bogaard5, Marije Bomers2Peter Bonta5, Lieuwe Bos1, Michela Botta1, Justin de Brabander2Godelieve Bree2Sanne de Bruin1, Marianna Bugiani5, Esther Bulle1, Nora Chekrouni4, Osoul Chouchane2Alex Cloherty3, Dave A. Dongelmans1, Romein W.G. Dujardin1, Paul Elbers1, Lucas Fleuren1, Suzanne Geerlings2Theo Geijtenbeek3, Armand Girbes1, Bram Goorhuis2Martin P. Grobusch2Florianne Hafkamp3, Laura Hagens1, Jorg Hamann7, Vanessa Harris2Robert Hemke8, Sabine M. Hermans2Leo Heunks1, Markus Hollmann6, Janneke Horn1, Joppe W. Hovius2Menno D. de Jong9, Rutger Koning4, Endry H.T. Lim1, Niels van Mourik1, Jeaninne Nellen2Esther J. Nossent5, Sabine Olie4, Frederique Paulus1, Edgar Peters2, Tom van der Poll2, Bennedikt Preckel6, Jan M. Prins2, Jorinde Raasveld1, Tom Reijnders2, Michiel Schinkel2, Marcus J. Schultz1, Alex Schuurmans10, Jaap Schuurmans1, Kim Sigaloff1, Marleen A. Slim1,2, Marry Smit1, Cornelis S. Stijnis2, Willemke Stilma1, Charlotte Teunissen11, Patrick Thoral1, Anissa M Tsonas1, Marc van der Valk2, Denise Veelo6, Heder de Vries1, Lonneke A. Vught1,2, Mich?le van Vugt2, Dorien Wouters12, A. H (Koos) Zwinderman13, Matthijs C. Brouwer4, W. Joost Wiersinga2, Alexander P.J. Vlaar1, Diederik van de Beek4.1Department of Intensive Care, Amsterdam UMC, Amsterdam, The Netherlands;2Department of Infectious Diseases, Amsterdam UMC, Amsterdam, The Netherlands;3Experimental Immunology, Amsterdam UMC, Amsterdam, The Netherlands;4Department of Neurology, Amsterdam UMC, Amsterdam, The Netherlands;5Department of Pulmonology, Amsterdam UMC, Amsterdam, The Netherlands;6Department of Anesthesiology, Amsterdam UMC, Amsterdam, The Netherlands;7Amsterdam UMC Biobank Core Facility, Amsterdam UMC, Amsterdam, The Netherlands;8Department of Radiology, Amsterdam UMC, Amsterdam, The Netherlands;9Department of Medical Microbiology, Amsterdam UMC, Amsterdam, The Netherlands;10Department of Internal Medicine, Amsterdam UMC, Amsterdam, The Netherlands;11Neurochemical Laboratory , Amsterdam UMC, Amsterdam, The Netherlands;12Department of Clinical Chemistry, Amsterdam UMC, Amsterdam, The Netherlands;13Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam UMC, Amsterdam, The Netherlands. Funding Information: Corona Research Fund Amsterdam UMC, Dr. C. J. Vaillant Fonds, ZonMw (Vici 91819627). Copyright: Copyright 2021 Elsevier B.V., All rights reserved.

PY - 2021/6/1

Y1 - 2021/6/1

UR - http://www.scopus.com/inward/record.url?scp=85107735052&partnerID=8YFLogxK

U2 - https://doi.org/10.1007/s00134-021-06392-4

DO - https://doi.org/10.1007/s00134-021-06392-4

M3 - Letter

C2 - 33835207

SN - 0342-4642

VL - 47

SP - 704

EP - 706

JO - Intensive care medicine

JF - Intensive care medicine

IS - 6

ER -