Fertiliteitsparende behandeling endometriumcarcinoom

Maartje M. W. Luijten; Willem Jan van Weelden; Cornelis D. de Kroon; Johanna M. A. Pijnenborg; Mignon D. J. M. van Gent

Fertiliteitsparende behandeling endometriumcarcinoom

Maartje M. W. Luijten, Willem Jan van Weelden, Cornelis D. de Kroon, Johanna M. A. Pijnenborg, Mignon D. J. M. van Gent

Obstetrics and Gynaecology (AMC)

Research output: Contribution to journal › Article › Professional

Abstract

BACKGROUND: The incidence of endometrial carcinoma (EC) is rising worldwide due to an increased life expectancy and obesity. Approximately 2% of patients with EC is under the age of 45. Because the incidence is also rising in young women, there is a clinical need for safe fertility sparing alternative treatments. CASE DESCRIPTION: A 32-year-old women was diagnosed with low-grade endometrioid EC. Hysteroscopic tumour resection and progestin treatment resulted in complete tumour regression. The patient became pregnant through in vitro fertilisation (IVF). CONCLUSION: This case illustrates that fertility sparing treatment, with oral progestin treatment is an alternative treatment option in selected young women with low grade, early stage endometrial carcinoma to achieve pregnancy. This treatment is internationally accepted.

Original language	Dutch
Journal	Nederlands Tijdschrift voor Geneeskunde
Volume	165
Publication status	Published - 25 Nov 2021

Cite this

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title = "Fertiliteitsparende behandeling endometriumcarcinoom",

abstract = "BACKGROUND: The incidence of endometrial carcinoma (EC) is rising worldwide due to an increased life expectancy and obesity. Approximately 2% of patients with EC is under the age of 45. Because the incidence is also rising in young women, there is a clinical need for safe fertility sparing alternative treatments. CASE DESCRIPTION: A 32-year-old women was diagnosed with low-grade endometrioid EC. Hysteroscopic tumour resection and progestin treatment resulted in complete tumour regression. The patient became pregnant through in vitro fertilisation (IVF). CONCLUSION: This case illustrates that fertility sparing treatment, with oral progestin treatment is an alternative treatment option in selected young women with low grade, early stage endometrial carcinoma to achieve pregnancy. This treatment is internationally accepted.",

author = "Luijten, {Maartje M. W.} and {van Weelden}, {Willem Jan} and {de Kroon}, {Cornelis D.} and Pijnenborg, {Johanna M. A.} and {van Gent}, {Mignon D. J. M.}",

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AU - Luijten, Maartje M. W.

AU - van Weelden, Willem Jan

AU - de Kroon, Cornelis D.

AU - Pijnenborg, Johanna M. A.

AU - van Gent, Mignon D. J. M.

PY - 2021/11/25

Y1 - 2021/11/25

N2 - BACKGROUND: The incidence of endometrial carcinoma (EC) is rising worldwide due to an increased life expectancy and obesity. Approximately 2% of patients with EC is under the age of 45. Because the incidence is also rising in young women, there is a clinical need for safe fertility sparing alternative treatments. CASE DESCRIPTION: A 32-year-old women was diagnosed with low-grade endometrioid EC. Hysteroscopic tumour resection and progestin treatment resulted in complete tumour regression. The patient became pregnant through in vitro fertilisation (IVF). CONCLUSION: This case illustrates that fertility sparing treatment, with oral progestin treatment is an alternative treatment option in selected young women with low grade, early stage endometrial carcinoma to achieve pregnancy. This treatment is internationally accepted.

AB - BACKGROUND: The incidence of endometrial carcinoma (EC) is rising worldwide due to an increased life expectancy and obesity. Approximately 2% of patients with EC is under the age of 45. Because the incidence is also rising in young women, there is a clinical need for safe fertility sparing alternative treatments. CASE DESCRIPTION: A 32-year-old women was diagnosed with low-grade endometrioid EC. Hysteroscopic tumour resection and progestin treatment resulted in complete tumour regression. The patient became pregnant through in vitro fertilisation (IVF). CONCLUSION: This case illustrates that fertility sparing treatment, with oral progestin treatment is an alternative treatment option in selected young women with low grade, early stage endometrial carcinoma to achieve pregnancy. This treatment is internationally accepted.

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UR - https://www.ncbi.nlm.nih.gov/pubmed/35129891

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JO - Nederlands Tijdschrift voor Geneeskunde

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Fertiliteitsparende behandeling endometriumcarcinoom

Abstract

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