Effect of Systemic Hydrocortisone Initiated 7 to 14 Days after Birth in Ventilated Preterm Infants on Mortality and Neurodevelopment at 2 Years' Corrected Age: Follow-up of a Randomized Clinical Trial: Follow-up of a Randomized Clinical Trial

Nienke M. Halbmeijer; Wes Onland; Filip Cools; Renate Swarte; Marja van der Heide-Jalving; Maruschka P. Merkus; Anton H. van Kaam

doi:https://doi.org/10.1001/jama.2021.9380

Effect of Systemic Hydrocortisone Initiated 7 to 14 Days after Birth in Ventilated Preterm Infants on Mortality and Neurodevelopment at 2 Years' Corrected Age: Follow-up of a Randomized Clinical Trial: Follow-up of a Randomized Clinical Trial

Nienke M. Halbmeijer, Wes Onland, Filip Cools, Renate Swarte, Marja van der Heide-Jalving, Maruschka P. Merkus, Anton H. van Kaam

Research output: Contribution to journal › Comment/Letter to the editor › Academic

16 Citations (Scopus)

Abstract

This follow-up to the STOP-BPD randomized clinical trial, which investigated the efficacy and safety of systemic hydrocortisone treatment initiated 7 to 14 days after birth in ventilator-dependent, very preterm infants in the Netherlands and Belgium at 36 weeks’ postmenstrual age, examines the prespecified composite of death and neurodevelopmental impairment among these infants at 2 years’ corrected age.

Original language	English
Pages (from-to)	355-357
Number of pages	3
Journal	JAMA - Journal of the American Medical Association
Volume	326
Issue number	4
DOIs	https://doi.org/10.1001/jama.2021.9380
Publication status	Published - 27 Jul 2021

Keywords

Bronchopulmonary Dysplasia/prevention & control
Child, Preschool
Follow-Up Studies
Humans
Hydrocortisone/therapeutic use
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases/mortality
Neurodevelopmental Disorders/epidemiology
Respiration, Artificial

Access to Document

https://doi.org/10.1001/jama.2021.9380

Cite this

Halbmeijer, N. M., Onland, W., Cools, F., Swarte, R., van der Heide-Jalving, M., Merkus, M. P., & van Kaam, A. H. (2021). Effect of Systemic Hydrocortisone Initiated 7 to 14 Days after Birth in Ventilated Preterm Infants on Mortality and Neurodevelopment at 2 Years' Corrected Age: Follow-up of a Randomized Clinical Trial: Follow-up of a Randomized Clinical Trial. JAMA - Journal of the American Medical Association, 326(4), 355-357. https://doi.org/10.1001/jama.2021.9380

Halbmeijer, Nienke M. ; Onland, Wes ; Cools, Filip et al. / Effect of Systemic Hydrocortisone Initiated 7 to 14 Days after Birth in Ventilated Preterm Infants on Mortality and Neurodevelopment at 2 Years' Corrected Age: Follow-up of a Randomized Clinical Trial : Follow-up of a Randomized Clinical Trial. In: JAMA - Journal of the American Medical Association. 2021 ; Vol. 326, No. 4. pp. 355-357.

@article{b7938bc165af44258d0f82dfcf472c25,

title = "Effect of Systemic Hydrocortisone Initiated 7 to 14 Days after Birth in Ventilated Preterm Infants on Mortality and Neurodevelopment at 2 Years' Corrected Age: Follow-up of a Randomized Clinical Trial: Follow-up of a Randomized Clinical Trial",

abstract = "This follow-up to the STOP-BPD randomized clinical trial, which investigated the efficacy and safety of systemic hydrocortisone treatment initiated 7 to 14 days after birth in ventilator-dependent, very preterm infants in the Netherlands and Belgium at 36 weeks{\textquoteright} postmenstrual age, examines the prespecified composite of death and neurodevelopmental impairment among these infants at 2 years{\textquoteright} corrected age.",

keywords = "Bronchopulmonary Dysplasia/prevention & control, Child, Preschool, Follow-Up Studies, Humans, Hydrocortisone/therapeutic use, Infant, Newborn, Infant, Premature, Infant, Premature, Diseases/mortality, Neurodevelopmental Disorders/epidemiology, Respiration, Artificial",

author = "Halbmeijer, {Nienke M.} and Wes Onland and Filip Cools and Renate Swarte and {van der Heide-Jalving}, Marja and Merkus, {Maruschka P.} and {van Kaam}, {Anton H.}",

note = "Funding Information: Funding/Support: This trial was funded by a project grant from The Netherlands Organization for Health Research and Development ZonMW Priority Medicines for Children (11-32010-02). Copyright: Copyright 2021 Elsevier B.V., All rights reserved.",

year = "2021",

month = jul,

day = "27",

doi = "https://doi.org/10.1001/jama.2021.9380",

language = "English",

volume = "326",

pages = "355--357",

journal = "JAMA - Journal of the American Medical Association",

issn = "0098-7484",

publisher = "American Medical Association",

number = "4",

}

Halbmeijer, NM , Onland, W, Cools, F, Swarte, R, van der Heide-Jalving, M, Merkus, MP & van Kaam, AH 2021, 'Effect of Systemic Hydrocortisone Initiated 7 to 14 Days after Birth in Ventilated Preterm Infants on Mortality and Neurodevelopment at 2 Years' Corrected Age: Follow-up of a Randomized Clinical Trial: Follow-up of a Randomized Clinical Trial', JAMA - Journal of the American Medical Association, vol. 326, no. 4, pp. 355-357. https://doi.org/10.1001/jama.2021.9380

Effect of Systemic Hydrocortisone Initiated 7 to 14 Days after Birth in Ventilated Preterm Infants on Mortality and Neurodevelopment at 2 Years' Corrected Age: Follow-up of a Randomized Clinical Trial: Follow-up of a Randomized Clinical Trial. / Halbmeijer, Nienke M.; Onland, Wes; Cools, Filip et al.
In: JAMA - Journal of the American Medical Association, Vol. 326, No. 4, 27.07.2021, p. 355-357.

Research output: Contribution to journal › Comment/Letter to the editor › Academic

TY - JOUR

T1 - Effect of Systemic Hydrocortisone Initiated 7 to 14 Days after Birth in Ventilated Preterm Infants on Mortality and Neurodevelopment at 2 Years' Corrected Age: Follow-up of a Randomized Clinical Trial

T2 - Follow-up of a Randomized Clinical Trial

AU - Halbmeijer, Nienke M.

AU - Onland, Wes

AU - Cools, Filip

AU - Swarte, Renate

AU - van der Heide-Jalving, Marja

AU - Merkus, Maruschka P.

AU - van Kaam, Anton H.

N1 - Funding Information: Funding/Support: This trial was funded by a project grant from The Netherlands Organization for Health Research and Development ZonMW Priority Medicines for Children (11-32010-02). Copyright: Copyright 2021 Elsevier B.V., All rights reserved.

PY - 2021/7/27

Y1 - 2021/7/27

N2 - This follow-up to the STOP-BPD randomized clinical trial, which investigated the efficacy and safety of systemic hydrocortisone treatment initiated 7 to 14 days after birth in ventilator-dependent, very preterm infants in the Netherlands and Belgium at 36 weeks’ postmenstrual age, examines the prespecified composite of death and neurodevelopmental impairment among these infants at 2 years’ corrected age.

AB - This follow-up to the STOP-BPD randomized clinical trial, which investigated the efficacy and safety of systemic hydrocortisone treatment initiated 7 to 14 days after birth in ventilator-dependent, very preterm infants in the Netherlands and Belgium at 36 weeks’ postmenstrual age, examines the prespecified composite of death and neurodevelopmental impairment among these infants at 2 years’ corrected age.

KW - Bronchopulmonary Dysplasia/prevention & control

KW - Child, Preschool

KW - Follow-Up Studies

KW - Humans

KW - Hydrocortisone/therapeutic use

KW - Infant, Newborn

KW - Infant, Premature

KW - Infant, Premature, Diseases/mortality

KW - Neurodevelopmental Disorders/epidemiology

KW - Respiration, Artificial

UR - http://www.scopus.com/inward/record.url?scp=85111634273&partnerID=8YFLogxK

U2 - https://doi.org/10.1001/jama.2021.9380

DO - https://doi.org/10.1001/jama.2021.9380

M3 - Comment/Letter to the editor

C2 - 34313697

SN - 0098-7484

VL - 326

SP - 355

EP - 357

JO - JAMA - Journal of the American Medical Association

JF - JAMA - Journal of the American Medical Association

IS - 4

ER -

Halbmeijer NM , Onland W, Cools F, Swarte R, van der Heide-Jalving M, Merkus MP et al. Effect of Systemic Hydrocortisone Initiated 7 to 14 Days after Birth in Ventilated Preterm Infants on Mortality and Neurodevelopment at 2 Years' Corrected Age: Follow-up of a Randomized Clinical Trial: Follow-up of a Randomized Clinical Trial. JAMA - Journal of the American Medical Association. 2021 Jul 27;326(4):355-357. doi: https://doi.org/10.1001/jama.2021.9380

Effect of Systemic Hydrocortisone Initiated 7 to 14 Days after Birth in Ventilated Preterm Infants on Mortality and Neurodevelopment at 2 Years' Corrected Age: Follow-up of a Randomized Clinical Trial: Follow-up of a Randomized Clinical Trial

Abstract

Keywords

Access to Document

Other files and links

Cite this