Benefits and harm of systemic steroids for short- And long-term use in rhinitis and rhinosinusitis: An EAACI position paper

Valerie Hox; Evelijn Lourijsen; Arnout Jordens; Kristian Aasbjerg; Ioana Agache; Isam Alobid; Claus Bachert; Koen Boussery; Paloma Campo; Wytske Fokkens; Peter Hellings; Claire Hopkins; Ludger Klimek; Mika Mäkelä; Ralph Mösges; Joaquim Mullol; Laura Pujols; Carmen Rondon; Michael Rudenko; Sanna Toppila-Salmi; Glenis Scadding; Sophie Scheire; Peter-Valentin Tomazic; Thibaut van Zele; Martin Wagemann; Job F. M. van Boven; Philippe Gevaert

doi:https://doi.org/10.1186/s13601-019-0303-6

Benefits and harm of systemic steroids for short- And long-term use in rhinitis and rhinosinusitis: An EAACI position paper

Valerie Hox, Evelijn Lourijsen, Arnout Jordens, Kristian Aasbjerg, Ioana Agache, Isam Alobid, Claus Bachert, Koen Boussery, Paloma Campo, Wytske Fokkens, Peter Hellings, Claire Hopkins, Ludger Klimek, Mika Mäkelä, Ralph Mösges, Joaquim Mullol, Laura Pujols, Carmen Rondon, Michael Rudenko, Sanna Toppila-SalmiGlenis Scadding, Sophie Scheire, Peter-Valentin Tomazic, Thibaut van Zele, Martin Wagemann, Job F. M. van Boven, Philippe Gevaert

Research output: Contribution to journal › Review article › Academic › peer-review

118 Citations (Scopus)

Abstract

Because of the inflammatory mechanisms of most chronic upper airway diseases such as rhinitis and chronic rhinosinusitis, systemic steroids have been used for their treatment for decades. However, it has been very well documented that - potentially severe - side-effects can occur with the accumulation of systemic steroid courses over the years. A consensus document summarizing the benefits of systemic steroids for each upper airway disease type, as well as highlighting the potential harms of this treatment is currently lacking. Therefore, a panel of international experts in the field of Rhinology reviewed the available literature with the aim of providing recommendations for the use of systemic steroids in treating upper airway disease.

Original language	English
Article number	1
Journal	Clinical and Translational Allergy
Volume	10
Issue number	1
DOIs	https://doi.org/10.1186/s13601-019-0303-6
Publication status	Published - 3 Jan 2020

Keywords

Glucocorticosteroids
Rhinitis
Rhinosinusitis

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Hox, V., Lourijsen, E., Jordens, A., Aasbjerg, K., Agache, I., Alobid, I., Bachert, C., Boussery, K., Campo, P., Fokkens, W., Hellings, P., Hopkins, C., Klimek, L., Mäkelä, M., Mösges, R., Mullol, J., Pujols, L., Rondon, C., Rudenko, M., ... Gevaert, P. (2020). Benefits and harm of systemic steroids for short- And long-term use in rhinitis and rhinosinusitis: An EAACI position paper. Clinical and Translational Allergy, 10(1), Article 1. https://doi.org/10.1186/s13601-019-0303-6

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abstract = "Because of the inflammatory mechanisms of most chronic upper airway diseases such as rhinitis and chronic rhinosinusitis, systemic steroids have been used for their treatment for decades. However, it has been very well documented that - potentially severe - side-effects can occur with the accumulation of systemic steroid courses over the years. A consensus document summarizing the benefits of systemic steroids for each upper airway disease type, as well as highlighting the potential harms of this treatment is currently lacking. Therefore, a panel of international experts in the field of Rhinology reviewed the available literature with the aim of providing recommendations for the use of systemic steroids in treating upper airway disease.",

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Hox, V, Lourijsen, E, Jordens, A, Aasbjerg, K, Agache, I, Alobid, I, Bachert, C, Boussery, K, Campo, P, Fokkens, W, Hellings, P, Hopkins, C, Klimek, L, Mäkelä, M, Mösges, R, Mullol, J, Pujols, L, Rondon, C, Rudenko, M, Toppila-Salmi, S, Scadding, G, Scheire, S, Tomazic, P-V, van Zele, T, Wagemann, M, van Boven, JFM & Gevaert, P 2020, 'Benefits and harm of systemic steroids for short- And long-term use in rhinitis and rhinosinusitis: An EAACI position paper', Clinical and Translational Allergy, vol. 10, no. 1, 1. https://doi.org/10.1186/s13601-019-0303-6

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AU - Hox, Valerie

AU - Lourijsen, Evelijn

AU - Jordens, Arnout

AU - Aasbjerg, Kristian

AU - Agache, Ioana

AU - Alobid, Isam

AU - Bachert, Claus

AU - Boussery, Koen

AU - Campo, Paloma

AU - Fokkens, Wytske

AU - Hellings, Peter

AU - Hopkins, Claire

AU - Klimek, Ludger

AU - Mäkelä, Mika

AU - Mösges, Ralph

AU - Mullol, Joaquim

AU - Pujols, Laura

AU - Rondon, Carmen

AU - Rudenko, Michael

AU - Toppila-Salmi, Sanna

AU - Scadding, Glenis

AU - Scheire, Sophie

AU - Tomazic, Peter-Valentin

AU - van Zele, Thibaut

AU - Wagemann, Martin

AU - van Boven, Job F. M.

AU - Gevaert, Philippe

PY - 2020/1/3

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N2 - Because of the inflammatory mechanisms of most chronic upper airway diseases such as rhinitis and chronic rhinosinusitis, systemic steroids have been used for their treatment for decades. However, it has been very well documented that - potentially severe - side-effects can occur with the accumulation of systemic steroid courses over the years. A consensus document summarizing the benefits of systemic steroids for each upper airway disease type, as well as highlighting the potential harms of this treatment is currently lacking. Therefore, a panel of international experts in the field of Rhinology reviewed the available literature with the aim of providing recommendations for the use of systemic steroids in treating upper airway disease.

AB - Because of the inflammatory mechanisms of most chronic upper airway diseases such as rhinitis and chronic rhinosinusitis, systemic steroids have been used for their treatment for decades. However, it has been very well documented that - potentially severe - side-effects can occur with the accumulation of systemic steroid courses over the years. A consensus document summarizing the benefits of systemic steroids for each upper airway disease type, as well as highlighting the potential harms of this treatment is currently lacking. Therefore, a panel of international experts in the field of Rhinology reviewed the available literature with the aim of providing recommendations for the use of systemic steroids in treating upper airway disease.

KW - Glucocorticosteroids

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KW - Rhinosinusitis

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M3 - Review article

C2 - 31908763

SN - 2045-7022

VL - 10

JO - Clinical and Translational Allergy

JF - Clinical and Translational Allergy

IS - 1

M1 - 1

ER -

Benefits and harm of systemic steroids for short- And long-term use in rhinitis and rhinosinusitis: An EAACI position paper

Abstract

Keywords

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