Abstract
The disappearance pattern of prostate-specific antigen from serum after a standard radical prostatectomy was studied in eight patients with cancer confined to the prostate. The results were used to plot an elimination curve and calculate the best fit. A biphasic pattern was found with an average biological half-life of 1.63 hours in the alpha-phase, and 4.63 days in the beta-phase. Based on these results it is concluded that determination of prostate-specific antigen concentrations less than one month after a standard radical prostato-vesiculectomy has no value for the detection or exclusion of residual malignant processes
Original language | English |
---|---|
Pages (from-to) | 53-55 |
Journal | European journal of clinical chemistry and clinical biochemistry |
Volume | 32 |
Issue number | 2 |
Publication status | Published - 1994 |