Calibration procedure for enhanced mirror artifact removal in full-range optical coherence tomography using passive quadrature demultiplexing

Xavier Attendu, Dirk J. Faber, Guy Lamouche, Ton G. van Leeuwen, Caroline Boudoux, Maxime Rivard

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Abstract

SignificancePassive quadrature demultiplexing allows full-range optical coherence tomography (FR-OCT). However, imperfections in the wavelength- and frequency-response of the demodulation circuits can cause residual mirror artifacts, which hinder high-quality imaging on both sides of zero delay.AimWe aim at achieving high mirror artifact extinction by calibrated postprocessing of the FR-OCT signal.ApproachWe propose a mathematical framework for the origin of the residual mirror peaks as well as a protocol allowing the precise measurement and correction of the associated errors directly from mirror measurements.ResultsWe demonstrate high extinction of the mirror artifact over the entire imaging range, as well as an assessment of the method's robustness to time and experimental conditions. We also provide a detailed description of the practical implementation of the method to ensure optimal reproducibility.ConclusionThe proposed method is simple to implement and produces high mirror artifact extinction. This may encourage the adoption of FR-OCT in clinical and industrial systems or loosen the performance requirements on the optical demodulation circuit, as the imperfections can be handled in postprocessing.
Original languageEnglish
JournalJournal of biomedical optics
Volume27
Issue number11
DOIs
Publication statusPublished - 1 Nov 2022

Keywords

  • calibration
  • full-range optical coherence tomography
  • mirror artifact
  • passive quadrature demultiplexing

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