Abstract
Sodium sieving in peritoneal dialysis (PD) occurs in a situation with high osmotically-driven ultrafiltration rates. This dilutional phenomenon is caused by free water transport through the water channel aquaporin-1. It has recently been described that encapsulating peritoneal fibrosis is associated with impaired free water transport, despite normal expression of aquaporin-1. In this review, it will be argued that free water transport can be used for assessment of fibrotic peritoneal alterations, due to the water-binding capacity of collagen. Finally, the consequences for clinical practice will be discussed
| Original language | English |
|---|---|
| Pages (from-to) | 124-128 |
| Journal | Peritoneal Dialysis International |
| Volume | 36 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2016 |