TY - JOUR
T1 - Cardiovascular magnetic resonance techniques for tissue characterization after acute myocardial injury
AU - Demirkiran, Ahmet
AU - Everaars, Henk
AU - Amier, Raquel P.
AU - Beijnink, Casper
AU - Bom, Michiel J.
AU - Götte, Marco J. W.
AU - van Loon, Ramon B.
AU - Selder, Jasper L.
AU - van Rossum, Albert C.
AU - Nijveldt, Robin
N1 - Funding Information: First author, Ahmet Demirkiran has received a research grant from the post-doctoral International Research Fellowship Programme by Scientific and Technological Research Council of Turkey. REF: 53325897-115.02-170549. Publisher Copyright: © The Author(s) 2019. Published on behalf of the European Society of Cardiology. All rights reserved. Copyright: Copyright 2019 Elsevier B.V., All rights reserved.
PY - 2019/1/1
Y1 - 2019/1/1
N2 - The annual incidence of hospital admission for acute myocardial infarction lies between 90 and 312 per 100 000 inhabitants in Europe. Despite advances in patient care 1 year mortality after ST-segment elevation myocardial infarction (STEMI) remains around 10%. Cardiovascular magnetic resonance imaging (CMR) has emerged as a robust imaging modality for assessing patients after acute myocardial injury. In addition to accurate assessment of left ventricular ejection fraction and volumes, CMR offers the unique ability of visualization of myocardial injury through a variety of imaging techniques such as late gadolinium enhancement and T2-weighted imaging. Furthermore, new parametric mapping techniques allow accurate quantification of myocardial injury and are currently being exploited in large trials aiming to augment risk management and treatment of STEMI patients. Of interest, CMR enables the detection of microvascular injury (MVI) which occurs in approximately 40% of STEMI patients and is a major independent predictor of mortality and heart failure. In this article, we review traditional and novel CMR techniques used for myocardial tissue characterization after acute myocardial injury, including the detection and quantification of MVI. Moreover, we discuss clinical scenarios of acute myocardial injury in which the tissue characterization techniques can be applied and we provide proposed imaging protocols tailored to each scenario.
AB - The annual incidence of hospital admission for acute myocardial infarction lies between 90 and 312 per 100 000 inhabitants in Europe. Despite advances in patient care 1 year mortality after ST-segment elevation myocardial infarction (STEMI) remains around 10%. Cardiovascular magnetic resonance imaging (CMR) has emerged as a robust imaging modality for assessing patients after acute myocardial injury. In addition to accurate assessment of left ventricular ejection fraction and volumes, CMR offers the unique ability of visualization of myocardial injury through a variety of imaging techniques such as late gadolinium enhancement and T2-weighted imaging. Furthermore, new parametric mapping techniques allow accurate quantification of myocardial injury and are currently being exploited in large trials aiming to augment risk management and treatment of STEMI patients. Of interest, CMR enables the detection of microvascular injury (MVI) which occurs in approximately 40% of STEMI patients and is a major independent predictor of mortality and heart failure. In this article, we review traditional and novel CMR techniques used for myocardial tissue characterization after acute myocardial injury, including the detection and quantification of MVI. Moreover, we discuss clinical scenarios of acute myocardial injury in which the tissue characterization techniques can be applied and we provide proposed imaging protocols tailored to each scenario.
KW - acute myocardial infarction
KW - cardiovascular magnetic resonance imaging
KW - infarct tissue characterization
KW - intramyocardial haemorrhage
KW - microvascular injury
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85068538411&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/31131401
UR - http://www.scopus.com/inward/record.url?scp=85068538411&partnerID=8YFLogxK
U2 - https://doi.org/10.1093/ehjci/jez094
DO - https://doi.org/10.1093/ehjci/jez094
M3 - Review article
C2 - 31131401
SN - 2047-2404
VL - 20
SP - 723
EP - 734
JO - European heart journal cardiovascular Imaging
JF - European heart journal cardiovascular Imaging
IS - 7
M1 - jez094
ER -