Celiac disease: New therapies on the horizon

Tessa Dieckman, Frits Koning, Gerd Bouma

Research output: Contribution to journalReview articleAcademicpeer-review

5 Citations (Scopus)

Abstract

Celiac Disease (CeD) is a chronic intestinal disease which occurs in 0.7–1.4% of the global population. Since the discovery of gluten as its disease-inducing antigen, CeD patients are treated with a gluten-free diet which is effective but has limitations for certain groups of patients. Accordingly, over the past few years, there is a growing interest in alternative treatment options. This review summarizes emerging pharmacological approaches, including tolerance induction strategies, tissue transglutaminase inhibition, gluten degradation, and inhibition of interleukin (IL)-15.
Original languageEnglish
Article number102268
JournalCurrent Opinion in Pharmacology
Volume66
DOIs
Publication statusPublished - 1 Oct 2022

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