Combination of Millar and conductance catheter to assess equine left ventricular function

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Abstract

Simultaneous measurement of left ventricular (LV) Pressure (P) and Volume (V) permits assessment of systolic elastance (Emax), stroke work and myocardial oxygen consumption (MVO2) using the P-V-area method. The conductance catheter has been applied to obtain V for clinical evaluations in human patients, and for experimental investigations in animals. While there is a tendency to miniaturize catheters for the study of small species such as rats, larger but also clinically relevant animals like the horse have not been evaluated with this instrument. Due to their large size, it may be anticipated that the number of sensing electrodes on the catheter can be increased, thus permitting the detailed regional study of many stacked slices in the larger LV. We investigated the P-V-relationship in three anesthetized ventilated horses, employing a 7F Millar P-catheter and a large-size conductance catheter with five equidistant sensing electrodes. The results indicate that PV loops can be determined on a beat-to-beat basis in the anesthetized horse.

Original languageEnglish
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
PublisherIEEE
Number of pages1
Volume1
ISBN (Print)0780356756
Publication statusPublished - 1 Dec 1999
EventProceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS) - Atlanta, GA, USA
Duration: 13 Oct 199916 Oct 1999

Conference

ConferenceProceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS)
CityAtlanta, GA, USA
Period13/10/199916/10/1999

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