Commentary on clinical guidelines and practice - In search of the truth by Dean J. Kereiakes and Elliott M. Antman

Robbert J. de Winter

doi:https://doi.org/10.1016/j.jacc.2006.04.095

Commentary on clinical guidelines and practice - In search of the truth by Dean J. Kereiakes and Elliott M. Antman

Research output: Contribution to journal › Editorial › Academic › peer-review

Abstract

In the field of non-ST-segment acute coronary syndromes, the evidence from recent randomized controlled trials favors early invasive management in high-risk patients. However, data from the recent ICTUS (Invasive versus Conservative Treatment in Unstable Coronary Syndromes) trial and from several large "real-world" registries suggest that the benefit may be modest. In contrast, in the field of ST-segment elevation myocardial infarction, mechanical reperfusion with primary percutaneous coronary intervention (PCI) has been shown to be superior to thrombolytic therapy. Therefore, efforts should be directed to the organization of regional networks aimed at prehospital triage and swift transfer of patients to dedicated PCI centers with experienced staff and high-volume interventional operators

Original language	English
Pages (from-to)	1136-1138
Journal	Journal of the American College of Cardiology
Volume	48
Issue number	6
DOIs	https://doi.org/10.1016/j.jacc.2006.04.095
Publication status	Published - 2006

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https://doi.org/10.1016/j.jacc.2006.04.095

Cite this

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title = "Commentary on clinical guidelines and practice - In search of the truth by Dean J. Kereiakes and Elliott M. Antman",

abstract = "In the field of non-ST-segment acute coronary syndromes, the evidence from recent randomized controlled trials favors early invasive management in high-risk patients. However, data from the recent ICTUS (Invasive versus Conservative Treatment in Unstable Coronary Syndromes) trial and from several large {"}real-world{"} registries suggest that the benefit may be modest. In contrast, in the field of ST-segment elevation myocardial infarction, mechanical reperfusion with primary percutaneous coronary intervention (PCI) has been shown to be superior to thrombolytic therapy. Therefore, efforts should be directed to the organization of regional networks aimed at prehospital triage and swift transfer of patients to dedicated PCI centers with experienced staff and high-volume interventional operators",

author = "{de Winter}, {Robbert J.}",

year = "2006",

doi = "https://doi.org/10.1016/j.jacc.2006.04.095",

language = "English",

volume = "48",

pages = "1136--1138",

journal = "Journal of the American College of Cardiology",

issn = "0735-1097",

publisher = "Elsevier USA",

number = "6",

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T1 - Commentary on clinical guidelines and practice - In search of the truth by Dean J. Kereiakes and Elliott M. Antman

AU - de Winter, Robbert J.

PY - 2006

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N2 - In the field of non-ST-segment acute coronary syndromes, the evidence from recent randomized controlled trials favors early invasive management in high-risk patients. However, data from the recent ICTUS (Invasive versus Conservative Treatment in Unstable Coronary Syndromes) trial and from several large "real-world" registries suggest that the benefit may be modest. In contrast, in the field of ST-segment elevation myocardial infarction, mechanical reperfusion with primary percutaneous coronary intervention (PCI) has been shown to be superior to thrombolytic therapy. Therefore, efforts should be directed to the organization of regional networks aimed at prehospital triage and swift transfer of patients to dedicated PCI centers with experienced staff and high-volume interventional operators

AB - In the field of non-ST-segment acute coronary syndromes, the evidence from recent randomized controlled trials favors early invasive management in high-risk patients. However, data from the recent ICTUS (Invasive versus Conservative Treatment in Unstable Coronary Syndromes) trial and from several large "real-world" registries suggest that the benefit may be modest. In contrast, in the field of ST-segment elevation myocardial infarction, mechanical reperfusion with primary percutaneous coronary intervention (PCI) has been shown to be superior to thrombolytic therapy. Therefore, efforts should be directed to the organization of regional networks aimed at prehospital triage and swift transfer of patients to dedicated PCI centers with experienced staff and high-volume interventional operators

U2 - https://doi.org/10.1016/j.jacc.2006.04.095

DO - https://doi.org/10.1016/j.jacc.2006.04.095

M3 - Editorial

SN - 0735-1097

VL - 48

SP - 1136

EP - 1138

JO - Journal of the American College of Cardiology

JF - Journal of the American College of Cardiology

IS - 6

ER -