@article{ab7b6c3d97ed4a10970dc69497a3c38a,
title = "Comparison of outcome and characteristics between 6343 COVID-19 patients and 2256 other community-acquired viral pneumonia patients admitted to Dutch ICUs",
abstract = "Purpose: Describe the differences in characteristics and outcomes between COVID-19 and other viral pneumonia patients admitted to Dutch ICUs. Materials and methods: Data from the National-Intensive-Care-Evaluation-registry of COVID-19 patients admitted between February 15th and January 1th 2021 and other viral pneumonia patients admitted between January 1st 2017 and January 1st 2020 were used. Patients' characteristics, the unadjusted, and adjusted in-hospital mortality were compared. Results: 6343 COVID-19 and 2256 other viral pneumonia patients from 79 ICUs were included. The COVID-19 patients included more male (71.3 vs 49.8%), had a higher Body-Mass-Index (28.1 vs 25.5), less comorbidities (42.2 vs 72.7%), and a prolonged hospital length of stay (19 vs 9 days). The COVID-19 patients had a significantly higher crude in-hospital mortality rate (Odds ratio (OR) = 1.80), after adjustment for patient characteristics and ICU occupancy rate the OR was respectively 3.62 and 3.58. Conclusion: Higher mortality among COVID-19 patients could not be explained by patient characteristics and higher ICU occupancy rates, indicating that COVID-19 is more severe compared to other viral pneumonia. Our findings confirm earlier warnings of a high need of ICU capacity and high mortality rates among relatively healthy COVID-19 patients as this may lead to a higher mental workload for the staff.",
keywords = "COVID-19, Coronavirus, Critical care, Intensive care, Mortality, Outcome, Pneumonia",
author = "{the Dutch COVID-19 Research Consortium} and S. Brinkman and F. Termorshuizen and Dongelmans, {D. A.} and F. Bakhshi-Raiez and Arbous, {M. S.} and {de Lange}, {D. W.} and {de Keizer}, {N. F.} and Verbiest, {D. P.} and {te Velde}, {L. F.} and {van Driel}, {E. M.} and T. Rijpstra and Elbers, {P. H.J.} and Houwink, {A. P.I.} and L. Georgieva and E. Verweij and {de Jong}, {R. M.} and {van Iersel}, {F. M.} and Koning, {T. J.J.} and E. Rengers and N. Kusadasi and Erkamp, {M. L.} and {van den Berg}, R. and Jacobs, {C. J.M.G.} and Epker, {J. L.} and Rijkeboer, {A. A.} and {de Bruin}, {M. T.} and P. Spronk and A. Draisma and Versluis, {D. J.} and {van den Berg}, {A. E.} and Mos, {M. Vrolijk de} and Lens, {J. A.} and Pruijsten, {R. V.} and H. Kieft and J. Rozendaal and F. Nooteboom and Boer, {D. P.} and Janssen, {I. T.A.} and {van Gulik}, L. and Koetsier, {M. P.} and Silderhuis, {V. M.} and Schnabel, {R. M.} and I. Drogt and {de Ruijter}, W. and Bosman, {R. J.} and T. Frenzel and Urlings-Strop, {L. C.} and A. Dijkhuizen and Hen{\'e}, {I. Z.} and Spijkstra, {J. J.} and {de Meijer}, {A. R.}",
note = "Funding Information: We would like to acknowledge the effort of all Dutch hospitals to record their COVID-19 patients three times a day and additionally all the ICUs that also collected the comprehensive clinical data of the COVID-19 patients to NICE-DB. Without their effort this study would not have been possible. We thank The Netherlands Organisation for Health Research and Development (ZonMw) for funding this project (project number 10430012010011). We also like to thank all employees of NICE Research & Support for the technical development of the COVID-19 Online Module, processing the data, and support under high work pressure. Funding Information: Funding acquisition - Acquisition of the financial support for the project leading to this publication. N.F. de Keizer. Publisher Copyright: {\textcopyright} 2021 The Authors",
year = "2022",
month = apr,
doi = "https://doi.org/10.1016/j.jcrc.2021.12.007",
language = "English",
volume = "68",
pages = "76--82",
journal = "Journal of Critical Care",
issn = "0883-9441",
publisher = "Elsevier BV",
}