Control of Inhibition by the Direct Action of Cannabinoids on GABA(A) Receptors

T. Golovko, R. Min, N. Lozovaya, C. Falconer, N. Yatsenko, T. Tsintsadze, V. Tsintsadze, C. Ledent, R.J. Harvey, D. Belelli, J.J. Lambert, A. Rozov, N. Burnashev

Research output: Contribution to journalArticle*Academicpeer-review

Abstract

Cannabinoids are known to regulate inhibitory synaptic transmission via activation of presynaptic G protein-coupled cannabinoid CB
Original languageEnglish
Pages (from-to)2440-2455
Number of pages16
JournalCerebral cortex
Volume25
Issue number9
DOIs
Publication statusPublished - Sep 2015

Keywords

  • Action Potentials/drug effects
  • Animals
  • Animals, Newborn
  • Cannabinoids/metabolism
  • GABA Agents/pharmacology
  • Hippocampus/cytology
  • Humans
  • In Vitro Techniques
  • Inhibitory Postsynaptic Potentials/drug effects
  • Mice
  • Mice, Inbred C57BL
  • Mice, Transgenic
  • Neural Inhibition/drug effects
  • Patch-Clamp Techniques
  • Rats
  • Rats, Sprague-Dawley
  • Rats, Wistar
  • Receptor, Cannabinoid, CB1/genetics
  • Receptors, GABA/metabolism
  • Synaptic Transmission/drug effects
  • Transfection

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