TY - JOUR
T1 - Current and Future Use of Long Axial Field-of-View Positron Emission Tomography/Computed Tomography Scanners in Clinical Oncology
AU - Roya, Mostafa
AU - Mostafapour, Samaneh
AU - Mohr, Philipp
AU - Providência, Laura
AU - Li, Zekai
AU - van Snick, Johannes H.
AU - Brouwers, Adrienne H.
AU - Noordzij, Walter
AU - Willemsen, Antoon T. M.
AU - Dierckx, Rudi A. J. O.
AU - Lammertsma, Adriaan A.
AU - Glaudemans, Andor W. J. M.
AU - Tsoumpas, Charalampos
AU - Slart, Riemer H. J. A.
AU - van Sluis, Joyce
N1 - Funding Information: MR receives funding through an unconditional grant from PUSH (a collaboration between Siemens Healthineers and the UMCG). The sponsor had no role in the conceptualization, writing, or publication of the current manuscript. Publisher Copyright: © 2023 by the authors.
PY - 2023/11/1
Y1 - 2023/11/1
N2 - The latest technical development in the field of positron emission tomography/computed tomography (PET/CT) imaging has been the extension of the PET axial field-of-view. As a result of the increased number of detectors, the long axial field-of-view (LAFOV) PET systems are not only characterized by a larger anatomical coverage but also by a substantially improved sensitivity, compared with conventional short axial field-of-view PET systems. In clinical practice, this innovation has led to the following optimization: (1) improved overall image quality, (2) decreased duration of PET examinations, (3) decreased amount of radioactivity administered to the patient, or (4) a combination of any of the above. In this review, novel applications of LAFOV PET in oncology are highlighted and future directions are discussed.
AB - The latest technical development in the field of positron emission tomography/computed tomography (PET/CT) imaging has been the extension of the PET axial field-of-view. As a result of the increased number of detectors, the long axial field-of-view (LAFOV) PET systems are not only characterized by a larger anatomical coverage but also by a substantially improved sensitivity, compared with conventional short axial field-of-view PET systems. In clinical practice, this innovation has led to the following optimization: (1) improved overall image quality, (2) decreased duration of PET examinations, (3) decreased amount of radioactivity administered to the patient, or (4) a combination of any of the above. In this review, novel applications of LAFOV PET in oncology are highlighted and future directions are discussed.
KW - LAFOV PET/CT
KW - dual-tracer imaging
KW - parametric imaging
KW - protocol optimization
UR - http://www.scopus.com/inward/record.url?scp=85176553842&partnerID=8YFLogxK
U2 - https://doi.org/10.3390/cancers15215173
DO - https://doi.org/10.3390/cancers15215173
M3 - Review article
C2 - 37958347
SN - 2072-6694
VL - 15
JO - Cancers
JF - Cancers
IS - 21
M1 - 5173
ER -