TY - JOUR
T1 - Sexual quality of life of adolescents and young adult breast cancer survivors
AU - Peeters, N. J.M.C.V.
AU - Vlooswijk, C.
AU - Bijlsma, R. M.
AU - Kaal, S. E.J.
AU - Kerst, J. M.
AU - Tromp, J. M.
AU - Bos, M. E.M.M.
AU - van der Hulle, T.
AU - Lalisang, R. I.
AU - Nuver, J.
AU - Kouwenhoven, M. C.M.
AU - van der Ploeg, I. M.C.
AU - van der Graaf, W. T.A.
AU - Husson, O.
N1 - Funding Information: The authors wish to thank all the patients for their participation in the study and the registration team of the Netherlands Comprehensive Cancer Organisation (IKNL) for the collection of data for The Netherlands Cancer Registry. CV is supported by the Dutch Cancer Society [grant number #11788 COMPRAYA study]. OH is supported by the Netherlands Organization for Scientific Research VIDI [grant number 198.007]. Data collection of the SURVAYA study was partly supported by the investment grant [grant number 480-08-009] from the Netherlands Organization for Scientific Research. The authors have declared no conflicts of interest. The data presented in this study are available on request from the corresponding author. The data are not publicly available due to privacy issues. Funding Information: CV is supported by the Dutch Cancer Society [grant number #11788 COMPRAYA study]. OH is supported by the Netherlands Organization for Scientific Research VIDI [grant number 198.007]. Data collection of the SURVAYA study was partly supported by the investment grant [grant number 480-08-009 ] from the Netherlands Organization for Scientific Research . Publisher Copyright: © 2024 The Author(s)
PY - 2024/2
Y1 - 2024/2
N2 - Background: With increasing survival rates of adolescents and young adults (AYAs) with breast cancer, health-related quality of life (HRQoL) becomes more important. An important aspect of HRQoL is sexual QoL. This study examined long-term sexual QoL of AYA breast cancer survivors, compared sexual QoL scores with that of other AYA cancer survivors, and identified factors associated with long-term sexual QoL of AYA breast cancer survivors. Materials and methods: Data of the SURVAYA study were utilized for secondary analyses. Sexual QoL was assessed using the European Organization for Research and Treatment of Cancer Quality of Life cancer survivorship core questionnaire (EORTC QLQ-SURV100). Descriptive statistics were used to describe sexual QoL of AYA cancer survivors. Linear regression models were constructed to examine the effect of cancer type on sexual QoL and to identify factors associated with sexual QoL. Results: Of the 4010 AYA cancer survivors, 944 had breast cancer. Mean sexual QoL scores of AYA breast cancer survivors ranged from 34.5 to 60.0 for functional domains and from 25.2 to 41.5 for symptom-orientated domains. AYA breast cancer survivors reported significantly lower sexual QoL compared to AYA survivors of other cancer types on all domains. Age, time since diagnosis, relationship status, educational level, chemotherapy, hormonal therapy, breast surgery, body image, and coping were associated with sexual QoL of AYA breast cancer survivors. Conclusions: AYA breast cancer survivors experience decreased sexual QoL in the long term (5-20 years) after diagnosis and worse score compared to AYA survivors of other cancer types, indicating a clear need to invest in supportive care interventions for those at risk, to enhance sexual well-being.
AB - Background: With increasing survival rates of adolescents and young adults (AYAs) with breast cancer, health-related quality of life (HRQoL) becomes more important. An important aspect of HRQoL is sexual QoL. This study examined long-term sexual QoL of AYA breast cancer survivors, compared sexual QoL scores with that of other AYA cancer survivors, and identified factors associated with long-term sexual QoL of AYA breast cancer survivors. Materials and methods: Data of the SURVAYA study were utilized for secondary analyses. Sexual QoL was assessed using the European Organization for Research and Treatment of Cancer Quality of Life cancer survivorship core questionnaire (EORTC QLQ-SURV100). Descriptive statistics were used to describe sexual QoL of AYA cancer survivors. Linear regression models were constructed to examine the effect of cancer type on sexual QoL and to identify factors associated with sexual QoL. Results: Of the 4010 AYA cancer survivors, 944 had breast cancer. Mean sexual QoL scores of AYA breast cancer survivors ranged from 34.5 to 60.0 for functional domains and from 25.2 to 41.5 for symptom-orientated domains. AYA breast cancer survivors reported significantly lower sexual QoL compared to AYA survivors of other cancer types on all domains. Age, time since diagnosis, relationship status, educational level, chemotherapy, hormonal therapy, breast surgery, body image, and coping were associated with sexual QoL of AYA breast cancer survivors. Conclusions: AYA breast cancer survivors experience decreased sexual QoL in the long term (5-20 years) after diagnosis and worse score compared to AYA survivors of other cancer types, indicating a clear need to invest in supportive care interventions for those at risk, to enhance sexual well-being.
KW - adolescents and young adults (AYAs)
KW - breast cancer
KW - health-related quality of life (HRQoL)
KW - sexual quality of life (QoL)
KW - survivorship
UR - http://www.scopus.com/inward/record.url?scp=85183490352&partnerID=8YFLogxK
U2 - https://doi.org/10.1016/j.esmoop.2024.102234
DO - https://doi.org/10.1016/j.esmoop.2024.102234
M3 - Article
C2 - 38281325
SN - 2059-7029
VL - 9
JO - ESMO open
JF - ESMO open
IS - 2
M1 - 102234
ER -