TY - JOUR
T1 - Dataset for the reporting of carcinoma of the esophagus in resection specimens: recommendations from the International Collaboration on Cancer Reporting
AU - Lam, Alfred K.
AU - Bourke, Michael J.
AU - Chen, Renyin
AU - Fiocca, Roberto
AU - Fujishima, Fumiyoshi
AU - Fujii, Satoshi
AU - Jansen, Marnix
AU - Kumarasinghe, Priyanthi
AU - Langer, Rupert
AU - Law, Simon
AU - Meijer, Sybren L.
AU - Muldoon, Cian
AU - Novelli, Marco
AU - Shi, Chanjuan
AU - Tang, Laura
AU - Nagtegaal, Iris D.
N1 - Funding Information: The authors would like to acknowledge ICCR Project Managers Fleur Webster and Christina Selinger, for editorial and dataset administration management. The views expressed are solely those of the authors. Author contributions Alfred K. Lam and Iris Nagtegaal contributed to conceptual advice and writing of original draft manuscript. Alfred K. Lam, Michael Bourke, Renyin Chen, Roberto Fiocca, Fumiyoshi Fujishima, Satoshi Fujii, Marnix Jansen, Priyanthi Kumarasinghe, Rupert Langer, Simon Law, Sybren Meijer, Cian Muldoon, Marco Novelli, Chanjuan Shi, Laura Tang, and Iris Nagtegaal contributed to conceptualization and manuscript revision. Funding disclosures: None. This research did not receive any specific grant from funding agencies in the public, commercial, or non-for-profit sectors. Publisher Copyright: © 2021 Elsevier Inc.
PY - 2021/8/1
Y1 - 2021/8/1
N2 - Background and objectives: A standardized data set for esophageal carcinoma pathology reporting was developed based on the approach of the International Collaboration on Cancer Reporting (ICCR) for the purpose of improving cancer patient outcomes and international benchmarking in cancer management. Materials and methods: The ICCR convened a multidisciplinary international expert panel to identify the best evidence-based clinical and pathological parameters for inclusion in the data set for esophageal carcinoma. The data set incorporated the current edition of the World Health Organization Classification of Tumours of the Digestive System, and Tumour-Node-Metastasis staging systems. Results: The scope of the data set encompassed resection specimens of the esophagus and esophagogastric junction with tumor epicenter ≤20 mm into the proximal stomach. Core reporting elements included information on neoadjuvant therapy, operative procedure used, tumor focality, tumor site, tumor dimensions, distance of tumor to resection margins, histological tumor type, presence and type of dysplasia, tumor grade, extent of invasion in the esophagus, lymphovascular invasion, response to neoadjuvant therapy, status of resection margin, ancillary studies, lymph node status, distant metastases, and pathological staging. Additional non-core elements considered useful to report included clinical information, specimen dimensions, macroscopic appearance of tumor, and coexistent pathology. Conclusions: This is the first international peer-reviewed structured reporting data set for surgically resected specimens of the esophagus. The ICCR carcinoma of the esophagus data set is recommended for routine use globally and is a valuable tool to support standardized reporting, to benefit patient care by providing diagnostic and prognostic best-practice parameters.
AB - Background and objectives: A standardized data set for esophageal carcinoma pathology reporting was developed based on the approach of the International Collaboration on Cancer Reporting (ICCR) for the purpose of improving cancer patient outcomes and international benchmarking in cancer management. Materials and methods: The ICCR convened a multidisciplinary international expert panel to identify the best evidence-based clinical and pathological parameters for inclusion in the data set for esophageal carcinoma. The data set incorporated the current edition of the World Health Organization Classification of Tumours of the Digestive System, and Tumour-Node-Metastasis staging systems. Results: The scope of the data set encompassed resection specimens of the esophagus and esophagogastric junction with tumor epicenter ≤20 mm into the proximal stomach. Core reporting elements included information on neoadjuvant therapy, operative procedure used, tumor focality, tumor site, tumor dimensions, distance of tumor to resection margins, histological tumor type, presence and type of dysplasia, tumor grade, extent of invasion in the esophagus, lymphovascular invasion, response to neoadjuvant therapy, status of resection margin, ancillary studies, lymph node status, distant metastases, and pathological staging. Additional non-core elements considered useful to report included clinical information, specimen dimensions, macroscopic appearance of tumor, and coexistent pathology. Conclusions: This is the first international peer-reviewed structured reporting data set for surgically resected specimens of the esophagus. The ICCR carcinoma of the esophagus data set is recommended for routine use globally and is a valuable tool to support standardized reporting, to benefit patient care by providing diagnostic and prognostic best-practice parameters.
KW - Carcinoma
KW - Data set
KW - Esophagus
KW - International Collaboration onCancer Reporting
KW - Pathology
KW - Structured report
UR - http://www.scopus.com/inward/record.url?scp=85107822290&partnerID=8YFLogxK
U2 - https://doi.org/10.1016/j.humpath.2021.05.003
DO - https://doi.org/10.1016/j.humpath.2021.05.003
M3 - Article
C2 - 33992659
SN - 0046-8177
VL - 114
SP - 54
EP - 65
JO - Human Pathology
JF - Human Pathology
ER -