@article{1bb208a36cc9412caee6815e9e394fcd,
title = "Design and psychometrics for new measures of health-related quality of life in adults with type 1 diabetes: Type 1 Diabetes and Life (T1DAL)",
abstract = "Aims: To use a three-phase process to develop and validate new self-report measures of diabetes-specific health-related quality of life (HRQOL) for adults with type 1 diabetes. We report on four versions of the Type 1 Diabetes and Life (T1DAL) measure for people age 18–25, 26–45, 46–60, and over 60 years. Methods: We first conducted qualitative interviews to guide measure creation, then piloted the draft measures. We evaluated psychometric properties at six T1D Exchange Clinic Network sites via completion of T1DAL and validated measures of related constructs. Participants completed the T1DAL again in 4–6 weeks. We used psychometric data to reduce each measure to 23–27 items in length. Finally, we obtained participant feedback on the final measures. Results: The T1DAL-Adult measures demonstrated good internal consistency (α = 0.85–0.88) and test–retest reliability (r = 0.77–0.87). Significant correlations with measures of general quality of life, generic and diabetes-specific HRQOL, diabetes burden, self-management, and glycemic control demonstrated validity. Factor analyses yielded 4–5 subscales per measure. Participants were satisfied with the final measures and reported they took 5–10 min to complete. Conclusions: The strong psychometric properties of the newly developed self-report T1DAL measures for adults with type 1 diabetes make them appropriate for use in clinical research and care.",
keywords = "Assessment, Patient-reported Outcomes, Psychosocial, Quality of life",
author = "Hilliard, {Marisa E.} and Marrero, {David G.} and Minard, {Charles G.} and Cao, {Viena T.} and {de Wit}, Maartje and DuBose, {Stephanie N.} and Alandra Verdejo and Jaser, {Sarah S.} and Davida Kruger and Roshanak Monzavi and Shah, {Viral N.} and Wadwa, {R. Paul} and Weinstock, {Ruth S.} and Debbe Thompson and Anderson, {Barbara J.}",
note = "Funding Information: Ms. Kruger serves as a consultant/on the speaker's bureau for NovoNordisk, Eli Lilly, Sanofi, Dexcom, Abbott, Insulet, and AstraZenica. Dr. Monzavi is participating in clinical trials sponsored by NIDDK, Jaeb Center for Health Research, and Eli Lilly. Dr. Shah reports grants and personal fees from Sanofi US and Dexcom, Inc, grants from the Jaeb Center for Health Research, National Institutes of Health, Novo Nordisk, vTv Therapeutics, and Mylan GmBH, outside the submitted work. Dr. Wadwa reports research support and consulting fees from Dexcom, advisory board fees from Medtronic, advisory board fees and research support from Eli Lilly, and research support from Bigfoot Biomedical, Novo Nordisk, Tandem Diabetes Care, and MannKind, outside the submitted work. Dr. Weinstock is participating in clinical trials sponsored by Medtronic, Eli Lilly, Boehringer Ingelheim, Insulet, Tolerion, and Kowa Research Institute, and is a consultant for Insulogic. Funding Information: Research funding for this study came from The Leona M. and Harry B. Helmsley Charitable Trust (2015PG-T1D084, PIs: Anderson and Hilliard). Drs. Hilliard and Anderson also received complementary support from the National Institutes of Health (1K12DK097696, PI: Anderson). Portions of these data were reported in abstract form at the Society of Behavioral Medicine annual conference, 2019. Funding Information: Research funding for this study came from The Leona M. and Harry B. Helmsley Charitable Trust (2015PG-T1D084, PIs: Anderson and Hilliard). Drs. Hilliard and Anderson also received complementary support from the National Institutes of Health (1K12DK097696, PI: Anderson). Portions of these data were reported in abstract form at the Society of Behavioral Medicine annual conference, 2019. Publisher Copyright: {\textcopyright} 2021 Elsevier B.V. Copyright: Copyright 2021 Elsevier B.V., All rights reserved.",
year = "2021",
month = apr,
doi = "https://doi.org/10.1016/j.diabres.2020.108537",
language = "English",
volume = "174",
journal = "Diabetes Research and Clinical Practice",
issn = "0168-8227",
publisher = "Elsevier Ireland Ltd",
}