Determinants of fatigue 6 and 12 months after surgery in women with early-stage breast cancer: a comparison with women with benign breast problems

Jolanda de Vries, Alida F. van der Steeg, Jan A. Roukema

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

The objective of this study was to examine the predictors of fatigue 6 and 12 months after surgical treatment in women with early-stage breast cancer (BC group) and in women with benign breast problems (BBP group) in a prospective follow-up study. Women entered the study prior to diagnosis and completed questionnaires on personality factors, psychological factors, and social support. Fatigue was assessed 6 and 12 months after diagnosis (BBP group) or surgical treatment (BC group). Clinical data were taken from medical records. In the BC group (n=117), fatigue at 6 months was predicted by trait anxiety (P <.001) and extraversion (P <.05). Trait anxiety (P <.05), extraversion (P <.05), and depressive symptoms (P <.05) predicted fatigue at 12 months. In the BBP group (n=190), the predictors were trait anxiety (P <.001) for fatigue at 6 months, and trait anxiety (P <.001) and neuroticism (P <.01) for fatigue at 12 months. Many patients who are already fatigued before diagnosis remain tired regardless of diagnosis. Trait anxiety is strongly related to fatigue in both groups
Original languageEnglish
Pages (from-to)495-502
JournalJournal of psychosomatic research
Volume66
Issue number6
DOIs
Publication statusPublished - 2009

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